Mount Sinai Team Diagnoses Asthma With Nasal Brush Test
Mount Sinai Health SystemRNA sequencing and machine learning applied to develop new asthma biomarker
RNA sequencing and machine learning applied to develop new asthma biomarker
Researchers at Indiana University have made the first direct observation of how bacteria use appendages thousands of times thinner than a human hair to absorb DNA in the environment. The work could help advance efforts stop antibiotic resistant bacteria.
A study conducted by an international research team, which included investigators from Seattle Children’s Research Institute, implicates variants in four genes as a primary cause of non-syndromic cleft lip and palate in humans. The genes, associated for the first time with cleft lip and palate, encode proteins that work together in a network, providing important insight into the biological basis of one of the most common physical malformations.
Research in mice shows that a protein made by the stem cells that give rise to neurons, but not by neurons themselves, is key to brain cells’ ability to migrate during development and assume their proper positions. This primordial protein acts by clinging onto thousands of sites in the genome, affecting the activity of multiple genes that regulate brain development. The findings could yield valuable clues for a variety of neurodevelopmental disorders.
Biologists from the National University of Singapore discovered that the gene apterous A is responsible for the appearance and sex-specific traits of the dorsal wings of the African squinting bush brown butterfly.
In a new study, researchers directly compared more than 16,000 DNA locations, and for the first time found clear evidence of genetic differences between Red-shafted and Yellow-shafted Flickers.
To promote the public awareness and recognition of recent achievements in the field of genetics, the Genetics Society of America (GSA) is pleased to announce a new collaboration with The Gruber Foundation to award the Gruber Genetics Prize.
Un grupo de investigadores de Mayo Clinic y Exact Sciences Corporation terminaron un estudio de fase II para comparar un conjunto de marcadores del ADN frente a la alfafetoproteína, como método para analizar el cáncer de hígado.
A group of researchers from Mayo Clinic and Exact Sciences Corporation have completed a phase II study comparing a set of DNA markers to alpha fetoprotein as a method to test for liver cancer. The researchers presented their findings today at the 2018 Digestive Disease Week conference in Washington, D.C.
A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.
Approximately 47 million people worldwide are living with Alzheimer’s disease (AD) and other dementias. One of the most prominent neuroscientists in the country has developed eight myths and truths about AD to shed light on this form of dementia that causes problems with memory, thinking and behavior.
In an international Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with the oral FGFR inhibitor erdafitinib (ERDA) was well-tolerated and achieved a robust response for patients with metastatic urothelial, or urinary tract, cancers harboring mutations in the FGFR3 gene.
Matching targeted therapies to tumor-specific gene mutations across tumor types improved progression-free survival (PFS) and overall survival (OS) in patients with advanced disease relative to those receiving non-matched treatment (NMT), according to research from The University of Texas MD Anderson Cancer Center. The researchers also found that receiving matched targeted therapy (MTT) was an independent factor for predicting longer OS.
This month's tip sheet from Fred Hutch includes information about cancer care delivery and costs, partnering with Microsoft, understanding/changing cancer's genetics and a Mt. Everest climb for cancer research fundraising. To pursue any of these story ideas, please contact the individual listed for each.
Roswell Park Comprehensive Cancer Center researchers have identified significant differences in the immune microenvironment of breast cancer tumors between African-American and white women, shedding light on the ways in which race can influence cancer development and outcomes. The findings, to be presented at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, are based on based on a comprehensive review of data from The Cancer Genome Atlas.
Scientists from the Sidney Kimmel Cancer Center (SKCC) at Jefferson Health will be presenting research and leading discussions on various topics, including metastatic uveal melanoma, genetic counseling in men, immunotherapy in early stage lung cancer and solid tumors, quality of life among patients receiving treatment for T cell lymphoma and updates on the Cancer Moonshot during the Biden Cancer Initiative Colloquium at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, being held June 1-5 in Chicago.
In a study published in the May 21, 2018 issue of the Proceedings of the National Academy of Sciences, a team of researchers – aided with supercomputing resources from the San Diego Supercomputer Center (SDSC) based at UC San Diego – created a dynamic computer simulation to delineate a key biological process that allows the body to repair damaged DNA.
Researchers have devised a magnetic control system to make tiny DNA-based robots move on demand--;and much faster than recently possible.
Cancer is one of the leading causes of death among Americans. At least 10 percent of cancers are caused by inherited mutations in genes such as BRCA1 and BRCA2. Parents with the cancer gene mutation have a 50 percent chance of passing it on to a son or daughter. It’s well-known that women with BRCA are at a very high risk for breast and ovarian cancer.
Mount Sinai researchers investigate transcriptome-wide alterations in response to cocaine self-administration in mice