Feature Channels: Liver Disease

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There is a small, but growing, subset of livers that have been transplanted and have a cumulative age of more than 100 years.

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A study by UChicago researchers identifies the role that the BNIP3 protein plays in the development of fatty liver and liver cancer.

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The October issue of AJG highlights new clinical science and includes a supplement, ACG Monograph on GI Diseases and Endoscopy in Pregnancy & Postpartum Period, which includes recommendations for the care of pregnant patients with GI and liver diseases.

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Here is a summary of the September research discoveries and faculty news from Cedars-Sinai.

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Mariam F. Eskander, MD, MPH, surgical oncologist at Rutgers Cancer Institute of New Jersey, the state’s leading cancer center only National Cancer Institute (NCI)-designated Comprehensive Cancer Center, together with RWJBarnabas Health, and assistant professor of surgery at Rutgers Robert Wood Johnson Medical School whose clinical expertise includes liver tumors, shares more information on liver cancer and excessive alcohol use.

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RUDN University epidemiologists have reconstructed the history of hepatitis B and D viruses evolution in Yakutia (Russia). The investigation has established the course of evolution over the past fifteen hundred years. It turned out that a silent epidemic of hepatitis D continues in the region, and measures must be taken to stop it.

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New advances around perfusion devices are changing the game by keeping transplant livers alive longer, allowing for transportation of longer distances. New technology also enhances marginal donor livers, keeping them stimulated and alive longer, and therefore making many more livers available for transplantation. This in-person conference will provide groundbreaking insights on the technology and techniques around the use of preservation devices and examine the different strategies for successful perfusion/preservation of donor livers.

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As people with HIV age, their risk of heart attack increases far more if they also have untreated hepatitis C virus, even if their HIV is treated, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

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Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH)—a type of fatty liver disease that might progress to cancer—is particularly prevalent among obese people.

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Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

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After a rare disease caused organ failure, UC San Diego Heath transplant teams performed a heart, liver and kidney transplant on a patient. The surgery is a first for UC San Diego Health and a first in the nation to use three organs from a donor after circulatory death.

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The latest research and expert commentary on pain management.

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UHN’s Ajmera Transplant Centre and The Centre for Living Organ Donation announce today the launch of a new campaign, Great Actions Leave a Mark, www.greatactions.ca. The campaign showcases through artistic photos and video, the stories and scars (the mark) from 39 living organ donors and transplant recipients across Canada.

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Children's Hospital Los Angeles is hosting the 26th annual meeting of the Society of Pediatric Liver Transplantation, a multidisciplinary, multicenter consortium focused on optimizing outcomes in pediatric liver transplantation through research, advocacy and dissemination of best practices in the field.

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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The September issue of AJG highlights new clinical science, including a potential therapy to improve IBS-C symptoms, reintroduction of infliximab for Crohn’s disease, and population-based data to examine incidence and mortality of certain GI and hepatology diseases.

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The University of Miami Miller School of Medicine Division of Digestive Health and Liver Diseases shines not only for its commitment to patient care and published research, but also as a beacon for advancing the careers of female physicians. The division is celebrating the latter during September, which is the American Medical Association’s National Women in Medicine Month.