Feature Channels: Stem Cells

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Released: 25-Apr-2022 2:10 AM EDT
Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila
Cell Reports

… a decline in nutrient availability is likely to provide insight into the metabolic regulation of stem cell behavior in other tissues and organisms. … Taken together, our data describe one mechanism by which a transcription factor controls stem cell …

Released: 25-Apr-2022 12:00 AM EDT
A person-centred intervention remotely targeting family caregivers’ support needs in the context of allogeneic hematopoietic stem cell transplantation - a feasibility study
Preprints

Annika M Kisch, Karin Bergkvist, Sólveig Adalsteinsdóttir, Christel Wendt, Anette Alvariza, Jeanette Winterling

Released: 25-Apr-2022 12:00 AM EDT
Prognostic implications of MUC1 and XBP1 concordant expression in multiple myeloma: A retrospective study
Preprints

Sheerien Rajput, Khurram Minhas, Iqbal Azam, Usman Shaikh, El-Nasir Lalani

Released: 25-Apr-2022 12:00 AM EDT
Molecular Imaging (PET and SPECT) for Children with Hypoxic-ischemic-encephalopathy and Cerebral Palsy before and after cell therapy
Preprints

Toshinobu Nakatake, Makoto Nabetani, Nanae Yutaka, Kaho Suzuki, Ryoichi Hazama, Satoshi Ohnishi, Takashi Hamazaki, Haruo Shintaku, Ran D Goldman

Released: 25-Apr-2022 12:00 AM EDT
Human PMSCs derived exosomes alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model
Preprints

Yitian Lu, Jintao Zhang, Fanning Zeng, Peng Wang, Xiangna Guo, Haitao Wang, Zaisheng Qin, Tao Tao

Released: 25-Apr-2022 12:00 AM EDT
Induction of human pluripotent stem cells from human somatic cells by chemical reprogramming
Preprints

Hongkui Deng, Jingyang Guan, Guan Wang, Jinlin Wang, Zhengyuan Zhang, Yao Fu, Lin Cheng, GaoFan Meng, Jialiang Zhu, Yanglu Wang, Shijia Liuyang, Zirun Yang, Huanjing He, Xinxing Zhong, Qijing Chen

Released: 25-Apr-2022 12:00 AM EDT
Taurine promotes differentiation and maturation of neural stem/progenitor cells from the subventricular zone via activation of GABAA receptors
Preprints

Lenin D. Ochoa-De la Paz, Nadia Estefanía Gutiérrez-Castañeda, Jessica González-Corona, Ernesto Griego, Emilio J. Galván

Released: 25-Apr-2022 12:00 AM EDT
Functional stemness-related genes revealed by single-cell profiling of naïve and stimulated human CD34 + cells from CB and mPB
Preprints

GuoYi Dong, Xiaojing Xu, Yue Li, Wenjie Ouyang, Weihua Zhao, Ying Gu, Jie Li, Tianbin Liu, Xinru Zeng, Huilin Zou, Shuguang Wang, Sixi Liu, Hai-Xi Sun, Chao Liu

Released: 25-Apr-2022 12:00 AM EDT
Fabrication of three-dimensional lacrimal gland-like tissue organoids from human pluripotent stem cells
Preprints

Toru Okubo, Ryuhei Hayashi, Yuji Kudo, Yuki Ishikawa, Andrew J. Quantock

Released: 25-Apr-2022 12:00 AM EDT
Mitochondrial transfer alters cell fate by remodeling metabolic processes to regulate bone homeostasis
Preprints

Yufeng Zhang, Wenjin Cai, Jinglun Zhang, Yiqian Yu, Yueqi Ni, Yan Wei, Yihong Cheng, Litian Han, Leyi Xiao, Xiaoxin Ma, Hongjiang Wei, YaoTing Ji

Released: 25-Apr-2022 12:00 AM EDT
The Impact of COVID-19 on Autologous Stem Cell Transplantation in Multiple Myeloma A single-centre service evaluation
Preprints

Marquita Camilleri, Georgios Bekris, Govundeep Sidhu, Caroline Buck, Esme Elsden, Orla McCourt, Jackie Horder, Fiona Newrick, Catherine Lecat, Jonathan Sive, Xenofon Papanikolaou, Rakesh Popat, Lydia Lee, Ke Xu, Charalampia Kyriakou, Neil Rabin, Kwee Yong, Abi Fisher

Released: 25-Apr-2022 12:00 AM EDT
Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells
Preprints

Biswajit Das, Chinmayee Sethy, Subhajit Chatterjee, Somya Ranjan Dash, Saptarshi Sinha, Subarno Paul, Kunal Goutam, Chanakya Nath Kundu

Released: 22-Apr-2022 4:00 AM EDT
Egr1 is a 3D matrix–specific mediator of mechanosensitive stem  cell lineage commitment
Science Advances

… stem  cell commitment, the field’s mechanistic understanding of this phenomenon largely derives from simplified two-dimensional (2D) culture substrates. Here, we found a 3D matrix–specific mechanoresponsive mechanism for neural stem  cell (NSC …

Released: 22-Apr-2022 4:00 AM EDT
DNA modified MSN-films as versatile biointerfaces to study stem  cell adhesion processes
Colloids and Surfaces B: Biointerfaces

… cells remains eliciting the desired stem  cell behavior once transplanted in the body. In their natural environment, stem  cell fate is regulated by their … ECM ligands, as well as soluble cues, making MSN-ssDNA based biointerfaces a novel tool to …

Released: 22-Apr-2022 4:00 AM EDT
Auxilin regulates intestinal stem  cell proliferation through EGFR
Stem Cell Reports

… Importantly, we demonstrate that Aux interacts with EGFR and safeguards the activation of EGFR to maintain a proper stem  cell proliferation rate. Thus, our data uncover the underlying mechanism of Aux in stem  cell proliferation control and …

Released: 22-Apr-2022 4:00 AM EDT
Development and regulation of stem  cell‐based therapies in China
Cell Proliferation in Basic and Clinical Sciences

… This article briefly introduced the regulatory framework development, the progress in stem  cell clinical researches and clinical trials of commercially developed stem  cell-based products, as well as the clinical review concerns of stem  cell-based products in …

Released: 22-Apr-2022 4:00 AM EDT
Improving allogeneic stem  cell transplantation in myelofibrosis
International Journal of Hematology

In this review, we will outline dimensions in which outcome of patients with myelofibrosis undergoing curative treatment can be optimized: patient selection, transplant procedure, and posttransplant prevention or treatment of relapse. For …

Released: 22-Apr-2022 4:00 AM EDT
Intensive chemotherapy followed by autologous stem cell transplantation in primary central nervous system lymphomas (PCNSLs). Therapeutic outcomes in real life—experience of the French Network
Bone Marrow Transplantation

… of etoposide and cytarabine [8], or intensive chemotherapy followed by autologous stem  cell transplantation (IC-ASCT) [9, 10]. Thiotepa-based myeloablative chemotherapy followed by autologous stem  cell transplantation (ASCT) …

Released: 22-Apr-2022 4:00 AM EDT
Mesenchymal stem  cell-derived exosomal microRNA-182-5p alleviates myocardial ischemia/reperfusion injury by targeting GSDMD in mice
Cell Death Discovery

… Owing to the fact that MSC-derived exosomes can further control stem  cell differentiation by carrying and transferring miRNAs, stem  cell-based exosome therapeutic regimens have been highlighted as effective means for cardiac …



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