New Study Explores the Role of Metformin in Ameliorating HMGB1-Mediated Oxidative Stress in Periodontitis
Chinese Academy of SciencesA recent study reveals that Metformin, a common drug used to manage Type 2 Diabetes, could offer new hope for treating periodontitis, a chronic inflammatory disease affecting oral tissues. The study explored the effects of Metformin on HMGB1 (High Mobility Group Box 1), an inflammation mediator implicated in oxidative stress during periodontitis.