Feature Channels: Pain

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Released: 10-May-2013 10:00 PM EDT
War Spawns New Approaches for Wounded Service Members’ Pain Care
American Pain Society

Better body armor and rapid aeromedical evacuations enable American service members to survive blasts that would have proved fatal in Vietnam or even the first Gulf War, but they pose new challenges to military medicine – how to deal with the excruciating pain of injuries, especially severe burns from IED blasts that body armor can’t protect.

9-May-2013 5:00 PM EDT
More Clinical Attention Needed for Assessing Pain in Older Adults
American Pain Society

Although several types of pain assessment tools are available to help clinicians evaluate pain in older people, too often the sole initial emphasis is to gauge pain intensity instead of determining how the pain affects function and the need for treatment, according to research presented at the American Pain Society Annual Scientific Meeting, www.americanpainsociety.org.

9-May-2013 5:00 PM EDT
Investments in Pain Grants Must Be a Top U.S. Health Care Priority
American Pain Society

Federal funding for pain research remains at disproportionately low levels despite overwhelming evidence that untreated and undertreated chronic pain is costing the nation more than $600 billion a year in medical costs and lost work time, and is expected to soar even higher as the population continues to age, according to the American Pain Society, www.americanpainsociety.org. Pain research accounts for only about 1 percent of research grants awarded by the National Institutes of Health (NIH), a massive, unjustifiable disparity given the imbalanced proportion of U.S. health care expenditures attributed to pain.

Released: 8-May-2013 5:00 PM EDT
Chronic Pain Sufferers Likely to Have Anxiety
Health Behavior News Service

Patients coping with chronic pain should also be evaluated for anxiety disorders, according to new research published in General Hospital Psychiatry.

Released: 2-May-2013 11:00 AM EDT
Persistent Pain After Stressful Events May Have a Neurobiological Basis
University of North Carolina Health Care System

A new study led by UNC School of Medicine researchers is the first to identify a genetic risk factor for persistent pain after traumatic events such as motor vehicle collision and sexual assault. The study also contributes further evidence that persistent pain after stressful events has a specific biological basis.

Released: 2-May-2013 10:50 AM EDT
Regular, Moderate Exercise Does Not Worsen Pain in People with Fibromyalgia
Atrium Health Wake Forest Baptist

For many people who have fibromyalgia, even the thought of exercising is painful. Yet a new study from Wake Forest Baptist Medical Center shows that exercise does not worsen the pain associated with the disorder and may even lessen it over time. The findings are published in the current online issue of the journal Arthritis Care & Research.

Released: 1-May-2013 6:00 PM EDT
One Bad Gene: Mutation that Causes Rare Sleep Disorder Linked to Migraines
University of Utah Health

A gene mutation associated with a rare sleep disorder surprisingly also contributes to debilitating migraines, a new discovery that could change the treatment of migraines by allowing development of drugs specifically designed to treat the chronic headaches.

29-Apr-2013 4:00 PM EDT
Genetic Mutation Linked with Typical Form of Migraine
University of California, San Francisco (UCSF)

A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

18-Apr-2013 7:00 AM EDT
Pain, Epigenetics and Endometriosis: Research Team Wants to Know How Molecular Tweaks Affect Which Women Hurt the Most
American Society for Biochemistry and Molecular Biology (ASBMB)

Most of us probably know at least one woman, and maybe quite a few more, with endometriosis. Despite the disease’s prevalence, there is no consensus on the cause of it, the existing treatment options leave a lot to be desired, and there are too few ways for women to, at the very least, effectively numb the pain that the disease provokes. A team of researchers hunting biomarkers to be used in diagnostics and perhaps a personalized approach to treating endometriosis will present its findings Tuesday at the Experimental Biology 2013 conference in Boston.

Released: 19-Apr-2013 9:00 PM EDT
Preliminary Research Shows Platelet-Rich Plasma as Most Effective Treatment for Chronic Heel Pain
American Medical Society for Sports Medicine (AMSSM)

Research presented Friday aims to find an effective treatment for the two million Americans suffering annually from moderate-to-severe heel pain. John J. Wilson, MD, MS, AMSSM member, presented his research on plantar fasciitis entitled, “Platelet-Rich Plasma for the Treatment of Chronic Plantar Fasciopathy in Adults: A Randomized Controlled Clinical Trial” on Friday, April 19, 2013 at the American Medical Society for Sports Medicine’s 22nd Annual Meeting in San Diego, Cal.

Released: 18-Apr-2013 10:55 AM EDT
Hologram-Like 3-D Brain Helps Researchers Decode Migraine Pain
University of Michigan

Wielding a joystick and wearing special glasses, pain researcher Alexandre DaSilva rotates and slices apart a large, colorful, 3-D brain floating in space before him.

Released: 15-Apr-2013 4:30 PM EDT
Stony Brook Specialist Freezes Nerves to Knock Pain Out Cold
Stony Brook Medicine

For the millions of Americans who rely on pain medications for neuralgia, a condition where nerves damaged by surgery, traumatic injury, or diseases such as diabetes cause chronic pain, an emerging non-pharmacological treatment may offer relief. By placing a tiny ball of ice on damaged nerves by way of a minimally invasive interventional radiology treatment called cryoneurolysis, William Moore, MD, a thoracic interventional radiologist at Stony Brook University School of Medicine, is able to safely short circuit chronic pain caused by nerve damage.

8-Apr-2013 3:50 PM EDT
New Web-Based Tools Found to Enhance Recruitment and Prescreening for Clinical Pain Trials
American Academy of Pain Medicine (AAPM)

Success of clinical trials is dependent on recruitment and maintenance of adequate numbers of study subjects. For pain trials, often characterized by low recruitment rates and high attrition, arriving at a desired cohort of subjects presents a challenge for most investigators. Web based recruiting is an alternative - expanding the research site’s reach to more potential subjects and allowing for prescreening before the first research visit. We describe development of this recruitment tool in a vulvodynia trial.

8-Apr-2013 4:00 PM EDT
Study Suggests Dexmedetomidine Before Surgery Reduced Remifentanil-Induced Hyperalgesia
American Academy of Pain Medicine (AAPM)

Dexmedetomidine is a highly selective α2 adrenergic agonist that has been shown to decrease the intensity of opioid-induced hyperalgesia (OIH). We aimed to investigate the anti hyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia. Conclusions: High-dose remifentanil induced hyperalgesia but, dexmedetomidine efficiently alleviated those symptoms. Dexmedetomidine may be a novel and effective treatment option for OIH.

8-Apr-2013 4:00 PM EDT
Pain Improves During First Year but Mental-Health Problems Linger in Returning Veterans with Major Limb Injuries
American Academy of Pain Medicine (AAPM)

Few studies document short- and long-term pain and behavioral health in combat-injured service members with major limb trauma. In a 2-year longitudinal study, multiple post-injury pain and related outcomes are reported.

8-Apr-2013 5:00 PM EDT
Experimental Study Suggests Bone-Marrow Grafts Show Promise for Some Sufferers of Low-Back Pain
American Academy of Pain Medicine (AAPM)

Autologous bio-cellular grafts are increasingly encountered in surgical literature as a means to enhance tissue repair. Biologic graft use has expanded beyond simple platelet rich plasma to encompass bone marrow aspirate concentrate (BMAC) and adipose derived autologous stem cell products. The clinical application of such grafts in the treatment of low back pain is intriguing, but remains unproven.

8-Apr-2013 5:00 PM EDT
Preliminary Results Show Promise of Microwave Ablation (MWA) to Relieve Painful Bone and Soft-Tissue Tumors
American Academy of Pain Medicine (AAPM)

To evaluate the feasibility and efficacy of percutaneous microwave ablation (MWA) under CT guidance in the management of refractory pain in bone and soft tissue tumors. Researchers Concluded: When other therapies provide insufficient pain relief, percutaneous MWA treatment appears to be a feasible and effective technique for the management of refractory pain in bone and soft-tissue tumors. Ablation time appears to be highly reduced compared to radiofrequency ablation.

8-Apr-2013 3:00 PM EDT
A Case Series Suggests That New Anchoring and Multiple Lead Placement Techniques Reduce the Complications of Spinal Cord Stimulator Implant
American Academy of Pain Medicine (AAPM)

Advanced Spinal Cord Stimulator Lead Anchoring And Multiple Lead Placement Technique Through An Individual Port: A Case Serie To introduce a novel and advanced lead anchoring technique as well as introduce the emerging technology of large single port introducers and percutaneous paddle leads.

8-Apr-2013 3:00 PM EDT
New Research Examines the Spiritual, Psychological and Other Under-Appreciated Effects of Opioids on Patients with Sickle Cell Disease
American Academy of Pain Medicine (AAPM)

divergent effects of prescribed opioids in various domains among SCD patients, which likely modulate subsequent opioid taking behavior,” the authors wrote. “In all types of effects, biological effects appeared to be mediators of more indirect effects which led to alterations in subsequent opioid taking behavior.

8-Apr-2013 2:00 PM EDT
Study Suggests High-Dose Opioids Disturb Hormones Long Term, but Mental and Physiologic Function Improves
American Academy of Pain Medicine (AAPM)

All materials presented at the AAPM's 29th Annual Meeting are embargoed for news or other publication until the date and time of the presentation of the meeting unless AAPM grants permission for early publication in advance. EMBARGOED FOR RELEASE APRIL 11, 2013 5:30 PM Central Time/6:30 PM Eastern Time



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