Feature Channels: Biotech

Filters close
Released: 10-Nov-2022 12:00 PM EST
GREM1 is epigenetically reprogrammed in muscle cells after exercise training and controls myogenesis and metabolism
 Preprints

Comment
Released: 10-Nov-2022 12:00 PM EST
Outcome after allogeneic stem cell transplantation with haploidentical versus HLA-matched donors in patients with higher-risk MDS
 Preprints

Maud D'Aveni-Piney, Claire Michel, Marie Robin, Stephane Morisset, Didier Blaise, Johan Maertens, Patrice Chevalier, Cristina Castilla-Llorente, Edouard Forcade, Patrice Ceballos, Ibrahim Yakoub-Agha, Xavier Poiré, Martin Carre,

Comment
Released: 10-Nov-2022 12:00 PM EST
Profiling of chimeric RNAs in human retinal development with retinal organoids
 Preprints

Wen Wang, Xiao Zhang, Ning Zhao, Ze-Hua Xu, Kangxin Jin, Zi-Bing Jin

Comment
Released: 10-Nov-2022 12:00 PM EST
Cell autonomous requirement of imprinted XCI in extra-embryonic polar trophoblast cells
 Preprints

Feng Wang, Ashmita Chander, Yeonsoo Yoon, Mary Wallingford, Carmen Espejo-Serrano, Francisco Bustos, Greg Michael Findlay, Jesse Mager, Ingolf Bach

Comment
9-Nov-2022 9:00 AM EST
First use of CRISPR to substitute genes to treat patients with cancer
 University of California, Los Angeles (UCLA), Health Sciences

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

Comment
Newswise: CRISPR Treatment Slows Swelling in Hereditary Angioedema Patients
4-Nov-2022 8:00 AM EDT
CRISPR Treatment Slows Swelling in Hereditary Angioedema Patients
 American College of Allergy, Asthma and Immunology (ACAAI)

A new study being presented at this year’s ACAAI Annual Scientific Meeting shows a treatment using the CRISPR genome editing technology succeeded in alleviating swelling and reducing the frequency of attacks.

Comment
Newswise: El tratamiento CRISPR reduce la inflamación en pacientes con angioedema hereditario
4-Nov-2022 8:00 AM EDT
El tratamiento CRISPR reduce la inflamación en pacientes con angioedema hereditario
 American College of Allergy, Asthma and Immunology (ACAAI)

Un nuevo estudio que se presenta en la Reunión Científica Anual del ACAAI de este año muestra que un tratamiento que usa una tecnología de edición genética de repeticiones palindrómicas cortas, agrupadas y regularmente interespaciadas logró aliviar la inflamación y reducir la frecuencia de los ataques.

Comment
Released: 9-Nov-2022 3:15 PM EST
Knowledge is power. The latest research on arthritis is right at your fingertips
 Newswise

Here are some of the latest articles that have been added to the Arthritis channel on Newswise.

Comment
Released: 9-Nov-2022 12:00 PM EST
Title : ALL relapse after anti-CD19 CAR-T cells therapy in a young patient: which therapeutic options ?
 Preprints

Audrey Grain, Jocelyn Ollier, Thierry Guillaume, Patrice Chevallier, Baptiste Le Calvez, Marion Eveillard, Béatrice Clémenceau

Comment
Released: 9-Nov-2022 12:00 PM EST
NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice
 Preprints

Ruolin Zhang, Weibing Mao, Lumeng Niu, Wendai Bao, Yiqi Wang, Zhihao Yang, Yasha Zhu, Haikun Song, Jincao Chen, Guangqiang Li, Meng Cai, Zilong Yuan, Jiawen Dong, Min Zhang,

Comment
Released: 9-Nov-2022 12:00 PM EST
Preliminary study: Pharmacotherapeutic effect of the aqueous stem cell extract of Swiss apple {Malus domestica (Borkh)} of the Uttwiler Spätlauber specie in rats
 Preprints

Ifedolapo Adejumo, Muyiwa Fageyinbo, Precious Obiekwe, Fortune Ibe-Uba, Ibrahim Oreagba, Esther Agbaje

Comment
Released: 9-Nov-2022 12:00 PM EST
Tumour cell-induced senescence-like state of macrophages plays a pivotal role in tumour stable growth after tumour cell emergence in immunocompetent condition
 Preprints

Haruka Wada, Ryo Otsuka, Wilfred Germeraad, Tomoki Murata, Toru Kondo, Ken-Ichiro Seino

Comment
Released: 9-Nov-2022 12:00 PM EST
Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance
 Preprints

Xiaozhen Zhang, Mengyi Lao, HanShen Yang, Kang Sun, Lihong He, Muchun Li, Honggang Ying, Yan Chen, Xueli Bai, Tingbo Liang

Comment
Released: 9-Nov-2022 12:00 PM EST
COMPUTATIONAL EVIDENCE FOR MULTI-LAYER CROSSTALK BETWEEN THE CADHERIN-11 AND PDGFR PATHWAYS
 Preprints

Zeynep Karagoz, Fiona Rosaleen Passanha, Lars Robeerst, Martijn van Griensven, Vanessa LaPointe, Aurelie Carlier

Comment
Released: 9-Nov-2022 12:00 PM EST
The Wound Microenvironment and Recent Therapeutic Advances to Treat Wounds
 Preprints

Kevin Dzobo, Fatemeh Tavakoli Foroushani

Comment
Newswise: Silicon nanochip could treat traumatic muscle loss
Released: 9-Nov-2022 11:05 AM EST
Silicon nanochip could treat traumatic muscle loss
 Indiana University

Technology that can change skin tissue into blood vessels and nerve cells also shows promise as a treatment for traumatic muscle loss.

Comment
Newswise: Sensing platform for studying in vitro vascular systems opens possibilities for drug testing
Released: 8-Nov-2022 8:20 PM EST
Sensing platform for studying in vitro vascular systems opens possibilities for drug testing
 Tohoku University

The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.

Comment
Released: 8-Nov-2022 12:00 PM EST
Mechanotransduction is the Janus-faced regulator of cell aging
 Preprints

Xiaojing Liu, Li Liao, Peng Wang, Yuanxin Ye, Xiangyu Dong, Xiaotao Xing, Zhonghan Li, Qiang Wei, Weidong Tian

Comment
Released: 8-Nov-2022 12:00 PM EST
Characterization of cell-fate decision landscapes by estimating transcription factor dynamics
 Preprints

Comment
Released: 8-Nov-2022 12:00 PM EST
Knockout of formyl peptide receptor 1 reduces osteogenesis and bone healing
 Preprints

Xinlin Yang, Wan'an Xiao, Quang Le, Sang-Hyun Lee, Abhijit Dighe, Jason R Kerrigan, Quanjun Cui

Comment
Released: 8-Nov-2022 12:00 PM EST
Fabrication and In Vitro Characterization of Novel Hydroxyapatite Scaffolds 3D Printed Using Polyvinyl Alcohol as A Thermoplastic Binder
 Preprints

Andrej Thurzo, Paulína Gálfiová, Zuzana Varchulová Nováková, Štefan Polák, Ivan Varga, Martin Strunga, Renáta Urban, Jana Surovková, Ľuboš Leško, Zora Hajdúchová, Jozef Feranc, Marian Janek, Ľuboš Danišovič

Comment
Released: 8-Nov-2022 12:00 PM EST
PPARγ-dependent hepatic macrophage switching acts as a central hub for hUCMSCs-mediated alleviation of decompensated liver cirrhosis in rats
 Preprints

Yunqi Yao, Lin Zhang, Fuyi Cheng, Qingyuan Jiang, Yixin Ye, Yushuang Ren, Yuting He, Dongsheng Su, Lin Cheng, Gang Shi, Lei Dai, Hongxin Deng

Comment
Released: 8-Nov-2022 12:00 PM EST
Exploiting Embryonic Niche Conditions to Grow Wilms Tumor Blastema in Culture
 Preprints

Heather Wojcik, Harold N Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J Murphy, Suzanne Borgel, Hannah M Phelps, Hernan Correa, Alan O Perantoni

Comment
Released: 8-Nov-2022 12:00 PM EST
Endothelial cell-derived stem cell factor promotes lipogenesis through c-Kit-mediated upregulation of lipogenic enzymes in brown adipocytes
 Preprints

Gou Young Koh, Hyuek Jong Lee, Young-Chan Kim, Jungmo Kim, Myung Jin Yang, Seon Pyo Hong, Jueun Lee, Geum-Sook Hwang

Comment
Released: 8-Nov-2022 12:00 PM EST
Induction of tissue-specific premature stem cell aging via Lef1 deficiency promotes senescence-like deterioration in remote organs
 Preprints

Yasuaki Ikuno, Koichiro Watanabe, Yumi Kakeya, Shinsuke Ikeno, Toshimasa Nakabo, Ayano Narumoto, Yukie Kande, Tomoki Hayashi, Kahori Minami, Kasumi Nobuhiro, Yo Mabuchi, Shiho Nakamura, Hideyuki Okano, Dai Ihara,

Comment
Released: 8-Nov-2022 12:00 PM EST
Measures of genetic diversification in somatic tissues at bulk and single cell resolution
 Preprints

Marius E. Moeller, Nathaniel V. Mon Pere, Benjamin Werner, Weini Huang

Comment
Newswise: Starved yeast poisons clones
Released: 7-Nov-2022 6:25 PM EST
Starved yeast poisons clones
 University of Tokyo

When starved of glucose, yeast kills its own clones and other surrounding microorganisms to survive in a newly discovered phenomenon named latecomer killing.

Comment
Released: 7-Nov-2022 12:00 PM EST
Molecular characterization of a DyP-type peroxidase from the human parasitic cestode Echinococcus multilocularis
 Preprints

Johannes Ulrich, Klaus Brehm

Comment
Released: 7-Nov-2022 12:00 PM EST
GDF3 simultaneously antagonizes BMP signaling and activates TGFβ receptor signaling
 Preprints

Deepti Ramachandran, Nagasuryaprasad Kotikalapudi, David E Maridas, Anton Gulko, Linus T Tsai, Vicki Rosen, Alexander S Banks

Comment
Released: 7-Nov-2022 12:00 PM EST
Neural stem cell-derived exosomes protect spinal cord injury by the transfer of miR-31-5p
 Preprints

Dongdong Jiang, Yongjun Luo, Xiaoshu Wu, Chenyu Huang, Qiaofeng Zhang, Chunzhi Jiang, Qingqiang Yao, Fei Jiang, Pengyu Tang

Comment
Released: 7-Nov-2022 12:00 PM EST
Pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on physiological context
 Preprints

Karine Rizzoti, Probir Chakravarty, Daniel Sheridan, Robin Lovell-Badge

Comment
Released: 7-Nov-2022 12:00 PM EST
Higher-order epistasis shapes natural variation in germ stem cell niche activity
 Preprints

Comment
Released: 7-Nov-2022 12:00 PM EST
The genetic structure within a single tree is determined by the behavior of the stem cells in the meristem
 Preprints

Yoh Iwasa, Sou Tomimoto, Akiko Satake

Comment
Released: 7-Nov-2022 12:00 PM EST
Engineering circuits of human iPSC-derived neurons and rat primary glia
 Preprints

Sophie Girardin, Stephan Johannes Ihle, Arianna Menghini, Magdalena Krubner, Leonardo Tognola, Jens Duru, Tobias Ruff, Isabelle Fruh, Matthias Muller, János Vörös

Comment
Released: 7-Nov-2022 12:00 PM EST
Rescue of the increased susceptibility to Mild Chronic Oxidative Stress of iNeurons carrying the MAPT Chromosome 17q21.3 H1/H1 risk allele by FDA-approved compounds
 Preprints

Eldem Sadikoglou, Daniel Domingo-Fernandez, Natalia Savytska, Noemia Fernandes, Patrizia Rizzu, Anastasia Illarionova, Tabea Strauss, Sigrid Schwarz, Alpha Kodamullil, Guenter Hoeglinger, Ashutosh Dhingra, Peter Heutink

Comment
4-Nov-2022 11:20 AM EDT
Personalising whole genome sequencing doubles diagnosis of rare diseases
 University College London

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.

Comment
Released: 6-Nov-2022 12:00 PM EST
Awakening adult neural stem cells: NOX signalling as a positive regulator of quiescence to proliferation transition in the Xenopus retina
 Preprints

Alicia Donval, Cinthia Violeta Hernández Puente, Anaïs Lainé, Diana Roman, Romain Vessely, Julien Leclercq, Muriel Perron, Morgane Locker

Comment
Released: 4-Nov-2022 12:00 PM EDT
Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
 Preprints

Alok Maity, Andrew Teschendorff

Comment
Released: 4-Nov-2022 12:00 PM EDT
Integrated analysis of ovarian cancer stem cells-associated lncRNA-miRNA-mRNA network via microarray and Gene Expression Omnibus database
 Preprints

Zheng Li, Ying Li, Jinling Bai, Zhijiao Wang, Yingying Zhou

Comment
Released: 4-Nov-2022 12:00 PM EDT
Assessment of the potential of cold plasma-pretreated beta-tricalcium phosphate in combination with periodontal ligament stem cells to enhance bone regeneration in vivo
 Preprints

M Miletić, N Puač, N Škoro, B Brković, M Andrić, Bb Prokić, V Danilović, S Milutinović-Smiljanić, O Mitrović-Ajtić, S Mojsilović

Comment
Released: 4-Nov-2022 12:00 PM EDT
Evaluating the efficacy of human dental pulp stem cells and scaffold combination for bone regeneration in animal models: A systematic review and meta-analysis
 Preprints

Amin Namjoynik, Asiful Islam, Mohammad Islam

Comment
Released: 4-Nov-2022 12:00 PM EDT
Glycolytic metabolism and differentiation remodeling of hematopoietic stem cells in lung cancer
 Preprints

Ziqi Guo, Shiming Pu, Liu Yang, Yaping Liu, Xin Li, Hongxia Zhao, Zuping Zhou, Cheng Yang

Comment
Newswise: New Startup Develops Potential Cure for Type 1 Diabetes
Released: 3-Nov-2022 5:20 PM EDT
New Startup Develops Potential Cure for Type 1 Diabetes
 Georgia Institute of Technology

Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges. Although transplanting insulin-producing cells represents a promising approach, this cell therapy requires immunosuppression to prevent rejection. Georgia Tech researchers have developed a new biomaterial called iTOL-100 that could cure Type 1 diabetes by inducing immune acceptance of curative transplanted cells without immunosuppression.

Comment
Released: 3-Nov-2022 12:00 PM EDT
Immunotherapy of multi-drug resistant hematologic malignancies with IL-2-activated intentionally mismatched lymphocytes
 Preprints

Shimon Slavin

Comment
Released: 3-Nov-2022 12:00 PM EDT
HB-EGF and zinc activate EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
 Preprints

Oier Pastor-Alonso, Irene Dura, Sara Bernardo-Castro, Emilio Varea, Teresa Muro-Garcia, Soraya Martin-Suarez, Juan Manuel Encinas-Perez, Jose Ramon Pineda

Comment
Released: 3-Nov-2022 12:00 PM EDT
Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-causing mutations
 Preprints

Yara Hussein, Utkarsh Tripathi, Ashwani Choudhary, Ritu Nayak, David Peles, Idan Rosh, Jose Djamus, Ronen Spiegel, Tali Garin-Shkolnik, Shani Stern

Comment
Released: 3-Nov-2022 12:00 PM EDT
N6-methyladenosine-mediated changes in SOCS3 expression regulate skeletal muscle stem cell senescence
 Preprints

Menghai Zhu, Chong Lian, Gang Chen, Peng Zou, Beng Gang Qin

Comment
Released: 3-Nov-2022 12:00 PM EDT
Oxygen-sensitive TERT Promoter Methylation Regulates Telomerase Activity
 Preprints

Comment
Released: 3-Nov-2022 12:00 PM EDT
Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls
 Preprints

Dennis Kruk, Anna Yeung, Alen Faiz, Nick H.T. Ten Hacken, Wim Timens, Toin H. Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas, Irene H. Heijink

Comment
Released: 3-Nov-2022 12:00 PM EDT
Preparation of Cell-Loaded Microbeads as Stable and Injectable Delivery Platforms for Tissue Engineering
 Preprints

Mehmet Ali Karaca, Derya Dilek Kancagi, Ugur Ozbek, Ercument Ovali, Ozgul Gok

Comment

Showing results 701–750 of 3805


close
2.63709