The April edition of SLAS Technology features the cover article “Therapeutic Potential of Reactive Oxygen Species: State of the Art and Recent Advances” by Valeria Graceffa, Ph.D. (Institute of Technology Sligo, Sligo, Ireland).
A Northwestern University-led research team has developed a novel skin-mounted sticker that absorbs sweat and then changes color to provide an accurate, easy-to-read diagnosis of cystic fibrosis within minutes.
New study identifies a novel approach for tailored treatment that could be more effective for patients with the chronic disease
In a randomized clinical trial published in the journal PAIN, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill — referred to as an honest or open-label placebo — reported clinically meaningful improvements in their IBS symptoms.
The American College of Gastroenterology Invites All to “Tune It Up: A Concert To Raise Awareness of Colorectal Cancer” Free Webstream Event Open to All on March 31, 2021 at 8:00 pm EDT
Studies suggest the gut microbiome can influence immunotherapy side effects. Butyrate emerges as an intriguing candidate against inflammation in the colon.
GI OnDEMAND®, gastroenterology’s leading multidisciplinary virtual integrated care platform today announced a partnership with Ambry Genetics®, a leading clinical genetic testing company, to integrate online genetic counseling and testing services into gastroenterology practices nationwide. This partnership addresses a critical clinical need for identifying hereditary GI cancer syndromes to help guide potentially life-altering health care decisions. GI OnDEMAND, a joint venture between the American College of Gastroenterology and Gastro Girl, Inc., will now offer the CARE (Comprehensive, Assessment, Risk, and Education) Program™ from Ambry Genetics.
A foodborne fungus that is harmless to most people exacerbates gastrointestinal symptoms in people with Crohn’s disease by preventing intestinal ulcers from healing, according to a new study from Washington University School of Medicine in St. Louis and the Cleveland Clinic. The findings suggest that antifungal medications or dietary interventions may help alleviate the symptoms of Crohn’s.
A Cleveland Clinic-led team of researchers has discovered an infection that prevents healing in Crohn’s disease. According to study results published in Science, a type of yeast commonly found in cheese and processed meat is elevated in areas of unhealed wounds in Crohn’s disease patients, a discovery that may point to much-needed new treatment or prevention approaches for the common inflammatory bowel disease. The work was led by Thaddeus Stappenbeck, M.D., PhD., chair of Cleveland Clinic Lerner Research Institute’s Department of Inflammation and Immunity.
Recently, Prof. ZHU Shu from University of Science and Technology of China (USTC) of CAS and Prof. Richard A. Flavell from Yale University were invited to publish a review article in Nature Reviews Gastroenterology and Hepatology.
The March issue of The American Journal of Gastroenterology features new clinical research involving sex and gender, including effects of GI and liver conditions on pregnancy, gender disparities in diet and nutrition, Barrett’s esophagus incidence in women with scleroderma, factors influencing whether women pursue advanced endoscopy careers, endoscopy-related musculoskeletal injuries, sex hormone association with increased prevalence of certain types of cancer, and more.
The American College of Gastroenterology has issued updated evidence-based screening guidelines for colorectal cancer (CRC), including a new recommendation to begin CRC screening at age 45 for average risk adults. Key updates include recommendations for screening individuals with family history of CRC or polyps, guidance on the use of aspirin to reduce the risk of CRC, quality indicators for adenoma detection rate and colonoscopy withdrawal time, as well as suggestions about evidence-based interventions to boost screening rates, especially among African Americans. The authors distinguish between one-step screening tests, such as colonoscopy, and two-step screening tests that require colonoscopy, if positive, in order to complete the screening process.
Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.
Research on the relationship between the gut microbiome and diet can provide insights into diseases like depression and other health conditions.
Viruses are the most numerous biological entities on the planet. Now researchers at the Wellcome Sanger Institute and EMBL's European Bioinformatics Institute (EMBL-EBI) have identified over 140,000 viral species living in the human gut, more than half of which have never been seen before.
Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. It might also prevent the need for surgery in the future. Findings were published in the journal Advanced Therapeutics.
The February issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including inflammatory bowel disease, chronic viral hepatitis, biologics during pregnancy, colorectal cancer screening, GI symptoms in COVID-19, health inequities in patients with obesity, and more.
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer.
GRAND RAPIDS, Mich. (Feb. 2, 2021) — What does bile acid production in the digestive tract have to do with Parkinson’s disease?
A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.
Probiotic Lactobacillus bacteria use enzymes situationally to manipulate bile acids and promote their own survival in the gut.
The prevalence of inflammatory bowel diseases has significantly increased both in Finland and globally.
Researchers at Washington University School of Medicine in St. Louis have found that patients with Barrett's esophagus may be vulnerable to coronavirus infection from what they swallow.
Drs. Armando Sardi, Vadim Gushchin, and Kurtis Campbell, Surgical Oncology Department at Mercy Medical Center, are regarded for their training and skills in utilizing HIPEC to treat advanced stages of abdominal cancer (peritoneal surface malignancies). New findings by a prestigious organization of clinicians adds to this reputation, placing Mercy’s program among the nation’s best.
Hackensack Meridian Mountainside Medical Group announced today that Rosemarie Arena, M.D., has joined the practice, expanding their gastroenterology group.
The January issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of GI and hepatology topics, including NAFLD, colorectal cancer screening, GERD, post-COVID-19-associated functional GI disorder surges, celiac disease, and more.
Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant’s intestinal lining, is often connected to the development of severe brain injury in those infants who survive. However, the means by which the diseased intestine “communicates” its devastation to the newborn brain has remained largely unknown.
Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
Stupid Strong Charitable Foundation is proud to contribute $250,000 to The University of Texas MD Anderson Cancer Center to support cutting-edge research in gastric cancer led by Jaffer Ajani, M.D., professor of Gastrointestinal Medical Oncology.
The new guideline recommends is a positive diagnostic strategy involving a careful history, physical examination, and limited diagnostic testing, which can substantially shorten time to appropriate therapy and be more cost-effective for patients.
In PLOS Biology, a Stanford scientist ranked and published the top 2% of scientists (~150,000) from all fields of science based on their publication records, impact factor of the journal and the citation rates by other prominent investigators. Mercy’s Sergey V. Kantsevoy, M.D (top 0.5% in the world) and Paul J. Thuluvath, M.D (top 0.15% in the world) of The Institute for Digestive Health and Liver Disease (IDHLD) were noted among this 2% of all world scientists from all disciplines of science.
January 2021 DCR Journal videos
A study from researchers at Washington University School of Medicine in St. Louis has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue to why the bacteria have been linked to nutritional problems such as malnutrition and stunted growth.
An enzyme in the colon lining releases hydrogen peroxide – a known disinfecting compound- to protect the body from gut microbial communities. Findings from the UC Davis Health study points to importance of considering a different approach to treating gut inflammation and bacterial imbalance in the colon.
Henry Ford Health System is the first in the country to perform a procedure using the CG-100 intraluminal device, which is temporarily inserted into the gastrointestinal tract and designed to reduce diverting stoma rates, and the need for an ostomy bag, in patients undergoing gastrointestinal resection procedures due to colorectal cancer treatment.
The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.
In children with autism, repetitive behaviors and gastrointestinal problems may be connected, new research has found. The study found that increased severity of other autism symptoms was also associated with more severe constipation, stomach pain and other gut difficulties.
A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn’s disease, may disrupt calcium regulation.
New York University, Columbia University, and Takeda Pharmaceutical Company Limited (“Takeda”) have formed a collaborative research alliance to begin and advance gastroenterology research programs, with the goal of developing new therapies for patients with gastrointestinal and liver disorders.
Maria T. Abreu, M.D., a renowned gastroenterologist at the University of Miami Miller School of Medicine, was honored with the “Lifetime Disruptor” award at the American College of Gastroenterology’s 2020 virtual meeting.
Pancreatic cancer often is hidden and doesn't cause symptoms until it has spread. It is a leading cause of cancer deaths in the world. November 19 is World Pancreatic Cancer Day, but the entire month of November is meant to bring awareness to this disease. Advances in screening and early detection for high-risk people, minimally invasive surgical innovations and new genetic classifications are changing the outlook for pancreatic cancer, says Dr. Michael Wallace, a Mayo Clinic gastroenterologist.
Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.
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