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This new review in SLAS Discovery analyzes the recent literature and impact of unfolded protein response (UPR) in health and disease.

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Twelve endowed professorships have been established at Northwestern University to date through the Ryan Family Chair Challenge, which matches gifts made by other Northwestern supporters to create new professorships, or chairs, across a wide range of disciplines.

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Illinois patients with metastatic neuroendocrine cancer no longer have to travel abroad or out of state for a sought-after targeted therapy called peptide receptor radionuclide therapy, or PRRT. Rush University Medical Center in Chicago is one of the few health care providers in the United States, and the first in Illinois, authorized to offer this therapy for a limited number of patients prior to U.S. Food and Drug Administration approval.

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Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. The results of their study suggest that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.

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In a new study from the U.S. Department of Energy’s (DOE) Argonne National Laboratory, in collaboration with the University of Illinois at Chicago and the University of Delaware, chemists have been able to look at the interface between water and muscovite mica, a flat mineral commonly found in granite, soils and many sediments. In particular, the researchers looked at the capture and release of rubidium – a metal closely related to but more easily singled out than common elements like potassium and sodium.

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For the 14th time, Loyola University Medical Center has been named one of the nation's "Most Wired" hospitals. Gottlieb Memorial Hospital, a member of Loyola University Health System, also has been named to the prestigious 2017 Most Wired list.

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On July 1, Rush University Medical Center will launch its new, fully accredited residency program, with 12 first-year physicians.

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The first app and score to determine the one-year risk of a liver transplant patient dying or being hospitalized for a heart attack or other cardiovascular complication has been developed by Northwestern Medicine scientists.

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The first app and score to determine the one-year risk of a liver transplant patient dying or being hospitalized for a heart attack or other cardiovascular complication has been developed by Northwestern Medicine scientists.

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In collaboration with staff from the Argonne Leadership Computing Facility, researchers at the National Cancer Institute have perfected a technique that accurately computes the 3-D structure of RNA sequences. This method, which relies on a computer program known as RS3D and supercomputer Mira gives researchers studying cancer and other diseases structural insights about associated RNAs that can be used to advance computer-assisted drug design and development.

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A new study in Annals of Allergy, Asthma and Immunology showed that even kids who were prescribed an epinephrine auto injector didn’t receive the life-saving medication when they needed it.

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New studies from Northwestern University show that high school and college students from low socioeconomic status (SES) backgrounds are much less motivated to overcome academic hardships when they have doubts about the likelihood of people from their backgrounds achieving upward mobility.

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Cognitive Behavioral Therapy (CBT) is the most frequently used psychological intervention for people with chronic pain, and new approaches for improving CBT outcomes may be found in the psychological flexibility model and Acceptance and Commitment therapy (ACT), according to research reported in The Journal of Pain, published by the American Pain Society, www.americanpainsociety.org.

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Switching from 36 years of tradition in hosting its annual scientific meeting, the American Pain Society has changed the format for its 2018 conference to a Scientific Summit titled “Understanding Pain Mechanisms.” The event is March 4-6 at the Disneyland Hotel in Anaheim.

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With summer in full swing, dermatologists from the American Academy of Dermatology are reminding everyone that people of all races and colors can develop skin cancer. Although people of color have a lower risk of developing skin cancer than Caucasians, when skin cancer develops in people of color, it is often diagnosed at a more advanced stage – making it more difficult to treat. The good news, say dermatologists, is that there is a lot people can do to protect their skin and reduce their risk of getting skin cancer, including melanoma, the deadliest form.

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In one of the nation’s longest and most successful surgical partnerships, Loyola Medicine ENT surgeon John Leonetti, MD, and neurosurgeon Douglas Anderson, MD, have worked together to remove 1,500 acoustic neuromas during the past three decades.

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Having a good reason to get out of bed in the morning means you are more likely to sleep better at night with less sleep apnea and restless leg syndrome, reports a new Northwestern Medicine and Rush University Medical Center study based on older adults.This is the first study to show having a purpose in life specifically results in fewer sleep disturbances and improved sleep quality and over a long period of time.

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Loyola Medicine is enrolling patients in the first major study of a rare, debilitating lung disease that disproportionately affects people from Puerto Rico. Puerto Ricans who have the disease, Hermansky-Pudlak syndrome (HPS), are believed to have descended from a single founding patient.

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Nobel laureate Sir Fraser Stoddart has been named one of 38 “Great Immigrants” for 2017 by the Carnegie Corporation of New York, which celebrates contributions of naturalized U.S. citizens annually on July 4.

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New Northwestern University research underscores how environmental conditions early in development can cause inflammation in adulthood — an important risk factor for a wide range of diseases of aging, including cardiovascular diseases, diabetes, autoimmune diseases and dementia.

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New Northwestern University research underscores how environmental conditions early in development can cause inflammation in adulthood -- an important risk factor for a wide range of diseases of aging, including cardiovascular diseases, diabetes, autoimmune diseases and dementia.

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The American Society and Anesthesiologists (ASA) today congratulated Jerome Adams, M.D., on his nomination to Surgeon General by President Donald J. Trump. Dr. Adams will be the first physician anesthesiologist to hold this position.

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Visitors to NYC Parks’ 52 public pools will have access to free sunscreen this summer thanks to the American Academy of Dermatology.

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The Congress of Neurological Surgeons (CNS) and NEUROSURGERY® Publications announces Neurosurgery achieved a 2016 Clarivate JCR Impact Factor (IF) of 4.889, the highest IF since the journal’s inception. This is more than 29 percent greater than the 2015 IF of 3.78.

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Northwestern University’s Chad A. Mirkin, the George B. Rathmann Professor of Chemistry at the Weinberg College of Arts and Sciences, has been named a 2017 American Chemical Society (ACS) Fellow, adding to his list of more than 100 national and international awards.

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Researchers have developed new dosing models that may provide the scientific basis for more accurate administration of remifentanil, a synthetic opioid commonly used during surgery, in children and obese patients.

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The way children engage with their teachers, peers and tasks is vital to the success of early-childhood education but greatly underestimated, according to new Northwestern University research.

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Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness – a variance that long has puzzled researchers. Now a study has found that the gene mutation’s toxic effects require higher than normal levels of a protein called suPAR to trigger the onset and progression of the disease.

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On June 21, a prototype detector for the massive Deep Underground Neutrino Experiment recorded its first particle tracks. This was the largest ever test of an extremely precise method for measuring neutrinos, which may hold the key to why our universe looks the way it does and how it came into being.

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A Loyola University Chicago study published this month has found an increase in the percentage of breast cancer patients who were diagnosed in early Stage 1, after the Affordable Care Act took effect. The increases in Stage 1 diagnoses were higher among African American and Latina breast cancer patients.

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About 20 percent of children develop persistent pain after surgery, and a new study published in The Journal of Pain showed that poorer night-time sleep quality was significantly associated with greater next-day pain intensity over four months after surgery.

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For the second time in three years, the American Hospital Association has chosen Rush University Medical Center an honoree for its annual Equity of Care Award, which recognizes hospitals and health systems for their efforts to reduce health care disparities and to advance diversity and inclusion. The association announced the award recipient and honorees on June 20.

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The University of Chicago is collaborating with the U.S. Department of Energy’s Argonne National Laboratory and Fermi National Accelerator Laboratory to launch an intellectual hub for advancing academic, industrial and governmental efforts in the science and engineering of quantum information.

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One of the cornerstones of multiple sclerosis treatment is shared decision-making between patients and their doctors and nurses, according to a paper in the journal Practical Neurology.

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In recognition of his global contributions to psychiatry, Loyola Medicine psychiatrist Angelos Halaris, MD, PhD, has received the Owl of Wisdom award from the International Society of Neurobiology and Psychopharmacology.

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Researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and Argonne National Laboratory have collaborated to design, build and test two devices that utilize different superconducting materials and could make X-ray lasers more powerful, versatile, compact and durable.

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Erectile dysfunction drugs such as Viagra and Cialis can cause an adverse reaction during surgery or other procedures requiring anesthesia. Anesthesia and nitric oxide, the key ingredient in Viagra and Cialis should NOT EVER be mixed.

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There hasn’t been a gold standard for how orthopaedic spine surgeons promote new bone growth in patients, but now Northwestern University scientists have designed a bioactive nanomaterial that is so good at stimulating bone regeneration it could become the method surgeons prefer.

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New study results show for the first time how dying cells ensure that they will be replaced, and suggests an ingenious, related new approach to shrinking cancerous tumors. A research team from Rush University Medical Center will publish a new paper this week in the journal Developmental Cell that describes two groundbreaking discoveries.

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Argonne researchers have identified a nickel oxide compound as an unconventional but promising candidate material for high-temperature superconductivity. The project combined crystal growth, X-ray spectroscopy and computational theory.

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