The American Society for Cell Biology would like to formally announce that their journal Molecular Biology of the Cell (MBoC) seeks submissions for the Fifth Annual Special Issue on Quantitative Cell Biology.
Researchers studying the link between sleep apnea and heart disease have found a new mechanism: lipid clearance from the blood is slower in people with apnea, predisposing them to heart disease. Fortunately, CPAP treatment seems to improve matters.
Collaboration powers machine learning software that performs data analytics on petabyte-sized data sets in series of successful test runs.
MedStar Washington Hospital Center is the first hospital in Washington, D.C., to use Brainlab Airo® Mobile Intraoperative CT, an advanced imaging scanner that gives surgeons a real-time look at the brain or spine during surgery in order to make immediate decisions when it counts the most.
Scientists at the University of California, Los Angeles present research on a curious cosmic phenomenon known as “whistlers” -- very low frequency packets of radio waves that race along magnetic field lines. Appearing in the Physics of Plasmas, the study provides new insights into the nature of whistlers and space plasmas and could one day aid in the development of practical plasma technologies with magnetic fields, including spacecraft thrusters that use charged particles as fuel.
Researchers comparing several clonal strains of isoniazid-sensitive and resistant tuberculosis bacteria found shared changes to mycobacterial metabolism that bolster the evidence for a new proposed drug target.
Igloo was developed by the Department of Homeland Security (DHS) Science and Technology Directorate (S&T), and is currently in use by select units of U.S. Immigration and Customs Enforcement (ICE) Homeland Security Investigations (HSI), the lead agency for investigating human smuggling.
The 1987 Montreal Protocol and the 1997 Kyoto Protocol called for countries around the world to phase out substances that deplete the ozone layer and cause global warming, but many HVAC systems still use synthetic refrigerants that violate those international agreements and inflict environmental damage. Recently, Iranian researchers investigated how natural refrigerants could be used in geothermal heat pumps to reduce energy consumption and operating costs. They report their findings in the Journal of Renewable and Sustainable Energy.
Experts in fluid dynamics and kids jumping into a pool both know that an object falling into a liquid makes a splash. A new study finds that a single layer of a penetrable fabric – in this case, toilet paper – causes a wettable ball to make an especially tall splash, but additional layers can stop the splash entirely.
Researchers from the University of Florida and the Federal University of Mato Grosso do Sul in Brazil have used state of the art simulations to assess the effect of both pH and redox potential, or rate of electron transfer, on a biomolecule.
A valuable cache of brain cancer biomedical data, one of only two such large collections in the country, has been made freely available worldwide by researchers at Georgetown Lombardi Comprehensive Cancer Center.
The American Thyroid Association has awarded a 2018 Research Grant to Ann-Kathrin Eisfeld, MD, Clinical Fellow in Internal Medicine at Ohio State University. The topic of Dr. Eisfeld’s project is “Novel NRAS isoform mediates BRAF-inhibitor resistance in papillary thyroid cancer—thinking outside the box to overcome ‘inevitable’ treatment failure.” Papillary thyroid cancer (PTC) is one of the 10 most common malignancies in the United States, with almost 60,000 new people diagnosed each year. While almost all patients initially respond well to the current standard treatment with radioactive iodine, almost half of them will eventually develop resistance. Therapies that can provide additional treatment options for those patients are greatly needed.
The American Thyroid Association has awarded a 2018 Research Grant to Cintia Eliana Citterio, PhD, Assistant Professor of Genetics and Molecular Biology at the Instituto de Inmunología, Genética y Metabolismo (INIGEM), Universidad de Buenos Aires (UBA) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Dr. Citterio’s project is called “De novo triiodothyronine (T3) formation in T3 toxicosis of Graves’ Disease.” The project focuses on identifying T3-forming sites in thyroglobulin (TG, the protein from which thyroid hormone is made) that are responsible for excess T3 production in patients with autoimmune hyperthyroidism or Graves’ Disease (GD).
The American Thyroid Association has awarded a 2018 Research Grant to Wayne Miles, PhD, Assistant Professor of Molecular Genetics at the Ohio State University. Dr. Miles’s research project is entitled “Proteomic-led discovery of essential genes in Medullary Thyroid Cancer.” Medullary thyroid cancer (MTC) is caused by the malignant growth of C-cells. Although MTC represents only a small fraction (2¬4%) of all thyroid cancer cases and overall survival rates from MTC are good, patients diagnosed with advanced disease have poor five-year survival rates (28%). The genetic aberrations of the cancer result in C-cells receiving a continuous signal to grow and proliferate. To sustain their elevated growth rates, MTC cells adapt their genome (DNA), transcriptome (RNA), and proteome (the entire set of proteins expressed by a cell, tissue, or organism).
The American Thyroid Association has awarded a 2018 Research Grant to Nicholas J. Tardi, PhD, Instructor in Internal Medicine at Rush University Medical Center in Chicago. Dr. Tardi’s project is titled “Deiodinase 3: A Thyroid Hormone-Associated Renoprotective Protein.” The long-term goal of this project is to identify the source and mechanism of kidney and thyroid comorbidity. Thyroid hormone (TH) is a circulating, lipid-soluble molecule that plays an important physiological and developmental role in nearly all cells. Accordingly, precise control of TH activity is crucial to maintain metabolic homeostasis in several tissues.
Hours before the rise of the very star it will study, NASA’s Parker Solar Probe launched from Florida Sunday, Aug. 12, to begin its journey to the Sun
The American College of Radiology’s Neiman Institute and the Georgia Institute of Technology announced a new five-year, $3 million research partnership to establish the Health Economics and Analytics Lab (HEAL) within Georgia Tech’s Ivan Allen College of Liberal Arts.
The American Thyroid Association has awarded a 2018 Research Grant to Miles Miller, PhD, principal investigator at the Massachusetts General Hospital Center for Systems Biology and Assistant Professor of Radiology at Harvard Medical School. Dr. Miller’s research project is titled “Co-opting tumor-associated macrophages in anaplastic thyroid cancer to enhance immune-checkpoint blockade response.” Treatment of advanced metastatic cancer has seen a revolution over the last several years, as new therapeutic strategies have become successful at harnessing the power of the immune system to durably attack malignant and mutated cancer cells. Immune-checkpoint blockade therapies targeting programmed-death 1 (PD1) signaling on T-cells have been successful in the treatment of solid cancers, including heavily mutated melanomas and lung cancers. Unfortunately, these treatments only work in a fraction of patients, and resistance is often associated with the presence of a type of tumor-promoting imm
The American Thyroid Association has awarded a 2018 Research Grant to Stephanie Behringer-Massera, MD, Clinical Fellow at the Icahn School of Medicine at Mount Sinai. Dr. Behringer-Massera’s project is titled “T regulatory cells in thyroid-antibody-positive pregnant women.” A fetus, which shares half its genetic material with the father, is considered a foreign body in the mother’s womb. The only way that it can implant in the uterus without being rejected is if the mother’s immune system is suppressed, which happens through T-regulatory-cell action. The more T regulatory cells (Tregs) are released, the more the immune system is suppressed and the more likely the pregnancy can successfully be brought to term. In women with autoimmune thyroid disease, this process is disrupted. These women are found to have an abnormal Treg response to pregnancy and have Treg levels as low as women who are not pregnant. They are more likely to have miscarriages in the first trimester.
The American Thyroid Association has awarded a 2018 Research Grant to Brendan Frett, PhD, Assistant Professor in the College of Pharmacy at the University of Arkansas for Medical Sciences. The title of Dr. Frett’s project is “Dual Inhibition of RET and Aurora B to Study the Simultaneous Regulation of Multiple Oncogene Pathways in Medullary Thyroid Cancer.” Since its inception in 1971, the War on Cancer has resulted in significant treatment breakthroughs. One of the most important was the discovery of cancer-promoting oncogenes (genes with the potential to cause cancer). Researchers theorized that oncogenes could be strategically targeted while sparing normal cells, which sparked the era of precision medicine for oncology. Early medicine discoveries were quickly followed by the realization that secondary mutations in cancers often resulted in resistance to the drugs and relapse of the disease. This was solved by generating inhibitors that achieved activity on multiple forms of the onc
The American College of Radiology Liver Imaging Reporting and Data System (LI-RADS®) steering committee developed and approved a new version of CT/MRI LI-RADS (v2018), thus reaching a critical milestone of integration into the American Association for the Study of Liver Diseases (AASLD) 2018 hepatocellular carcinoma (HCC) clinical practice guidance.
Incivility in the workplace associated with more negative parenting behaviors at home, study says
The bond between parent and child extends far beyond sharing similar looks or behaviors, as symptoms of depression in teens and parents appear to be linked, according to research presented at the annual convention of the American Psychological Association.
Systems biology leads the way to exascale computing on Summit supercomputer.
Being ever-connected comes at a cost, studies find
Thinking developed in childhood makes people vulnerable, researchers say
• Older adults who initiate dialysis for kidney failure face a higher likelihood of being diagnosed with dementia and Alzheimer’s disease. • Certain risk factors were linked this higher risk. • Older hemodialysis patients with a diagnosis of dementia or Alzheimer’s disease had a high risk of early death.
From sexting to breaking up, texting can bring us close or drive us apart, studies find
Postpartum depression as prevalent in new fathers as mothers, research says
Increased control, physical activity lower subjective age in older adults, research says
Estrogen may protect against heart failure-related depression by preventing the production of inflammation-causing chemicals in the brain. The study is published ahead of print in the American Journal of Physiology—Heart and Circulatory Physiology.
Psychologists explore potential benefits of hallucinogens for mental health disorders
Beyond airlines, colleges and courts struggle to understand need, effects, researchers say
A clinical trial being conducted at Georgetown explores if nicotine can slow or stop memory loss in people experiencing mild memory problems, or mild cognitive impairment (MCI).
The Smithsonian’s podcast “Sidedoor” returns Aug. 8 with an episode that takes listeners inside one of the most exclusive places in all of Washington, D.C.: the National Gem Collection vault.
The American Thyroid Association (ATA®) is pleased to announce that Dr. Angela M. Leung has been selected as the new Editor-in-Chief of the ATA monthly journal Clinical Thyroidology®, as of 2019. Clinical Thyroidology is one of the ATA official journals distributed electronically. This highly valued abstract and commentary publication provides a broad-ranging look at the clinical thyroid literature. Experts in the field summarize the most cutting-edge, relevant articles of which clinicians should be aware and provide insight into the relevance and impact of each article on patient care.
The second annual edition of “Forces On and Within Cells, a special issue of Molecular Biology of the Cell, the peer-reviewed journal of the American Society for Cell Biology (ASCB), launched August 8, online.
The first-ever computation of an atomic nucleus, the deuteron, on a quantum chip demonstrates that even today’s rudimentary quantum computers can solve nuclear physics questions.
The first-ever computation of an atomic nucleus, the deuteron, on a quantum chip demonstrates that even today’s rudimentary quantum computers can solve nuclear physics questions.
The Myositis Association is pleased to announce the appointment of Mary McGowan as Executive Director.
Since 1997, several continents have played host to an international soccer tournament. No, not the World Cup -- the RoboCup. Robots of all shapes and sizes test their “metal” in the world’s favorite sport. Engineers and fans from across the globe have gathered to watch hunks of autonomous steel try to nudge a ball into a miniature net.
Proton-irradiated thorium targets are successfully mined for therapeutic radium isotopes.
Metastasis is a leading contributor to many deaths related to cancer, but the exact mechanisms for how broken cellular function appears in cells far removed from a cancer’s primary tumor remain an area of ongoing research. Scientists at the University of Minnesota Twin Cities confirmed a link between healthy-tumor hybrid cells and metastatic tumors for the first time in live animals. In APL Bioengineering, they discuss how they studied the distinct, heterogenous gene expression profiles found in human hybrid cells and how hybrid cells spontaneously occur in mouse models.
In nature, the nuclear reactions that form stars are often accompanied by astronomically high amounts of energy, a challenge for nuclear astrophysicists trying to study these reactions; the chances of re-creating such a spark are unfathomably low. However, after recent renovations to its accelerator, one laboratory reported record-breaking performance. Following six years of upgrades to the Electron Cyclotron Resonance Ion Source at the Laboratory for Experimental Nuclear Astrophysics, researchers report improved results, discussed in Review of Scientific Instruments.
400 kilometers above Earth, researchers examined waves in complex plasma under microgravity conditions and found that the microparticles behaved in nonuniform ways in the presence of varying electrical fields. They report some of the first findings from the Plasma-Kristall 4 experiment, a collaboration between the European Space Agency and the Russian State Space Corporation Roscosmos, in Physics of Plasmas.
Small businesses in the research and development domain will have the opportunity to engage with the DHS Small Business Innovation Research program representatives beginning August 20, in the final leg of a National Road Tour sponsored by the Small Business Administration.
Two St. Mary’s College of Maryland faculty members, Karen Leona Anderson, associate professor of English, and Liza Gijanto, associate professor of anthropology, have been honored with the college’s Aldom-Plansoen Honors College Professorship. One faculty member, Angela Johnson, professor of educational studies, has been honored with The G. Thomas and Martha Myers Yeager '41 Endowed Chair in the Liberal Arts.
Papers on nephrotoxicity, nanomaterial genotoxicity, machine learning; arsenic and telomere length in children; iPSC-derived cardiomyoctes for drug safety studies; and asthma, air pollution, and immunity featured in latest issue of Toxicological Sciences
Transgender individuals may be at higher risk for heart disease, according to a review article published by Michael S. Irwig, MD, associate professor of medicine at the George Washington University School of Medicine and Health Sciences, in Reviews in Endocrine and Metabolic Disorders.
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