A scalpel-free, high-tech form of brain surgery pioneered at UVA Health offers long-term relief for patients with essential tremor, a common movement disorder, a five-year review shows.
Rejuvenating the immune cells that live in tissues surrounding the brain improves fluid flow and waste clearance from the brain — and may help treat or even prevent neurodegenerative diseases such as Alzheimer’s and Parkinson’s, according to a study by researchers at Washington University School of Medicine in St. Louis.
A randomized controlled trial of 150 persons with Parkinson disease has found that (oral squalamine phosphate) ENT-01 is safe for up to 25 days of treatment and significantly improves constipation and possibly neurological symptoms. The findings are published in Annals of Internal Medicine.
Sex differences in the aging brain may offer an enticing clue for researching more effective neuroprotective treatments, according to a new treatment development strategy laid out by UCLA researchers.
Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.
As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.
Texas Biomed will help map the developing brain with unprecedented detail for the National Institutes of Health’s BRAIN Initiative Cell Atlas Network (BICAN). NIH recently awarded a total of $500 million to 11 teams that will work together to build a 3D brain atlas at single cell resolution over the next five years.
New research will aim to identify the electrical activity occurring as the brain receives information and then test whether targeted, gentle electrical stimulation can strengthen a specific memory.
Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.
Cecilia Lindestam Arlehamn, Ph.D., aims to shed light on how sex-based immune system differences may affect the development and progression of these neurodegenerative diseases in men versus women.
Higher exposure to a certain type of traffic-related air pollution called particulate matter may be linked to an increased risk of dementia, according to a meta-analysis published in the October 26, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers specifically looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air. The meta-analysis included all available studies on air pollution and risk of dementia.
The Presidential Symposium at the ongoing American Neurological Association 147th Annual Meeting outlined major risks to neurological health from environmental exposures to pesticides, air pollution, synthetic materials, and more — now emerging as a major research area in neuroscience.
As the American Neurological Association’s 147th Annual Meeting wraps up today, October 25, the ANA is holding a Media Roundtable at 11 a.m. U.S. Central for reporters to access the latest developments in neurology and neuroscience.
The early-stage research tested the delivery and safety of the new implantable catheter design in two sheep to determine its potential for use in diagnosing and treating diseases in the brain.
People who gain or lose weight soon after being diagnosed with Parkinson’s disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a study published in the October 19, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The Presidential Symposium at the American Neurological Association’s 2022 Annual Meeting (ANA2022) in Chicago will shine a spotlight on the role of environmental exposures — air pollution, pesticides, microplastics, and more — in diseases like dementias and developmental disorders.
Abstracts of breaking research in neurology and neuroscience, to be presented at the 2022 American Neurological Association Annual Meeting Oct. 22-25, are now available in Annals of Neurology and on the ANA2022 website.
By using artificial intelligence, Houston Methodist researchers are able to predict hospitalization outcomes of geriatric patients with dementia on the first or second day of hospital admission. This early assessment of outcomes means more timely interventions, better care coordination, more judicious resource allocation, focused care management and timely treatment for these more vulnerable, high-risk patients. The study is available online in Alzheimer’s & Dementia: Translational Research and Clinical Interventions, a journal of the Alzheimer’s Association.
The National Institutes of Health (NIH) awarded a $10.7 million five-year renewal grant to Cleveland Clinic to expand a national research consortium focused on improving the diagnosis and treatments for Dementia with Lewy Bodies. The Dementia with Lewy Bodies Consortium, established in 2017, centralized research efforts and created a national, coordinated registry for clinical data.
Parkinson’s disease is the fastest-growing neurodegenerative disease, now affecting more than 10 million people worldwide, yet clinicians still face huge challenges in tracking its severity and progression.
Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson’s disease and halts movement problems in mice.
يعاني الكثير من الناس من الانزعاج بسبب انتقال الطعام أو المشروبات دون قصد إلى المكان الخطأ عند البلع، لكن مشاكل البلع تصبح أحيانًا مزمنة وقد تكون علامة لحالة صحية يجب علاجها. يبيّن جيمس إيست، دكتور الطب، طبيب الجهاز الهضمي في مايو كلينك للرعاية الصحية في لندن، سبب صعوبة البلع لدى الأشخاص وكيفية علاج هذه المشكلة.
Muitas pessoas já experimentaram o desconforto de ter alimentos ou bebidas descendo acidentalmente pelo lugar errado ao engolir. Entretanto, problemas para engolir muitas vezes se tornam crônicos e podem ser um sinal de alguma doença que precisa ser tratada.
Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson’s disease, ultimately causing nerve cell death.
Muchas personas experimentan la incomodad de que un alimento o bebida se vaya accidentalmente por el lugar equivocado durante la deglución. Sin embargo, los problemas de deglución a veces se vuelven crónicos y pueden ser la señal de una enfermedad que debería tratarse.
Inactivation of a particular protein complex that plays a key role in keeping genes switched off leads to nerve cells not producing enough essential neurotransmitters.
Many people have experienced the discomfort of food or a beverage accidentally going to the wrong place when swallowing. But swallowing issues sometimes become chronic and may be a sign of a health condition that should be treated.
Flexible implanted electronics are a step closer toward clinical applications thanks to a recent breakthrough technology developed by a research team from Griffith University and UNSW Sydney.
We all know that people have reported brain fog and other neurological issues after having COVID-19. But a new study shows some sobering news – COVID-19 infections may have serious long-term effects. Major findings include that COVID-19 infections may predispose individuals to developing irreversible neurological conditions that may increase the likelihood of strokes and the chance of developing persistent brain lesions that can lead to brain bleeding. The findings appear online in press in the journal Ageing Research Reviews.
JMIR Publications recently published "Benefits of Virtual Reality Balance Training for Patients With Parkinson Disease: Systematic Review, Meta-analysis, and Meta-Regression of a Randomized Controlled Trial" in JMIR Serious Games, which reported that virtual reality (VR) balance training is increasingly being pursued in biomedical research, specifically with respect to investigating balance ability with VR.
UC San Diego researchers report that individuals with two copies of a gene mutation show evidence of substantial iron buildup in regions of the brain, raising risk for movement disorders like Parkinson’s disease.
Johns Hopkins Medicine researchers have helped develop a nanobody capable of getting through the tough exterior of brain cells and untangling misshapen proteins that lead to Parkinson’s disease, Lewy body dementia, and other neurocognitive disorders caused by the damaging protein.
In their study, the research groups looked at a protein called Creld. A study from Bonn had recently been able to demonstrate that Creld plays an important role in the development of the heart in mammals.
Neurodegenerative diseases like Alzheimer’s disease or Parkinson’s disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the result of minute deviations in the chemical composition of the biomolecules. Researchers at the Karlsruhe Institute of Technology (KIT) have developed a simple and effective method for detecting such misfolding at an early stage of the disease. Misfolding is revealed by the structure of dried residue from protein and peptide solutions.