While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology’s edits are still imperfect. Researchers have developed a new system to test and analyze CRISPR-based DNA repair and related risks from unintended but harmful “bystander” edits.
Mesenchymal stromal cells (MSCs) hold great promise for tissue regeneration in debilitating disorders. Despite reported improvements, the short-term outcomes of MSC transplantation, which is possibly linked to poor cell survival, demand ext
High glucose (HG) culture conditions in vitro and persistent exposure to hyperglycemia in diabetes patients are detrimental to stem cells, analogous to any other cell type in our body. It interferes with diverse signaling pathways, i.e. mam
With diabetes increasing at an alarming rate in the United States, Diabetes Alert Day® is meant to be a one-day “wake-up call” to the seriousness of diabetes and the importance of understanding your risk. The sooner you know your risk, the sooner you can take steps to prevent or even learn to manage the disease
New research conducted in mice offers insights into what’s going on at the molecular level that could cause people with diabetes to develop Alzheimer’s disease.
Surgical nerve decompression, used to treat conditions such as carpal tunnel syndrome and sciatica, could play a role in relieving the pain of diabetic neuropathy patients, researchers at UT Southwestern Medical Center found.
This paper summarizes the materials of microneedles, techniques, structure, design, release mechanism, classification of delivered substances and their effects on different stages of wound healing.
A study has unveiled that exosomes, extracted from adipose mesenchymal stem cells (ADSC-Exos), markedly speed up the healing process of skin wounds in diabetic mice. This discovery tackles the pressing global health issue of diabetic wounds, notorious for precipitating grave complications and impairments.
Omeza®, a regenerative skincare company that develops marine-based therapies for the treatment of chronic wounds, today presented positive interim data from a diabetic foot ulcer (DFU) clinical trial showing that Omeza® OCM™ plus offloading of weight on the affected foot achieved a 91 percent area reduction (PAR) rate in DFUs within twelve weeks, and a 63 percent PAR within four weeks.
New study finds that getting less than 45% of total energy from carbohydrates is not associated with elevated mortality risk compared with groups that consume more carbohydrates.
An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.
Glucagon-like peptide-1 (GLP-1) agonists such as Ozempic® or Wegovy® (semaglutide), Saxenda® (liraglutide), or Zepbound™ (tirzepatide), have become increasingly popular in promoting weight loss.
Are you one of the 530 million people who have diabetes? If so, it is also likely you have kidney disease. It's one of the most pressing global health challenges and scientists are scrambling to find new treatments and diagnostic markers for diabetic kidney disease. University of South Australia Research Fellow Dr Jantina Manning explains an exciting new discovery in her lab that could provide hope for millions of people living with diabetes and associated kidney disease. Thursday 14 March is World Diabetes Day.
The Endocrine Society applauds Congress for approving the first funding increase for the Special Diabetes Program in two decades.
It has been well established that people who live in rural areas in the U.S. are more likely to have diabetes and experience barriers to managing their condition compared to those who live in the suburbs and cities.
Loyola Medicine Nephrologist Sylvester Barnes is available to discuss a new study which showed Ozempic cut the risk of kidney disease progression and related health complications in diabetic patients.
A landmark study conducted at four sites, including Joslin Diabetes Center, reports that people with type 2 diabetes who underwent bariatric surgery achieved better long-term blood glucose control compared to people who received medical management plus lifestyle interventions. Participants who underwent bariatric surgery, also called metabolic or weight-loss surgery, were also more likely to stop needing diabetes medications and had higher rates of diabetes remission up to 12 years post-surgery. The findings, published in JAMA, suggest that weight loss surgery may carry benefits for people with diabetes, even those who are below the traditional BMI threshold of 35 for bariatric surgery.
Endocrine Society members elected Carol Lange, Ph.D., of the University of Minnesota in Minneapolis, Minn., as its 2025-2026 President. She will serve as President-Elect for a year beginning in June 2024 before becoming President in June 2025.
Semaglutide is a safe, effective therapy for a common fatty liver disease in people with HIV, according to the results of a clinical trial presented by UTHealth Houston.
After spending more than three decades managing her diabetes, Pam Mirabile was alarmed by swelling in her foot. She visited Loyola Medicine podiatric surgeon Katherine Dux, DPM, who diagnosed her with Charcot foot, a rare complication of diabetes.
Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.
People who are overall healthy and living with well-controlled Type 2 diabetes can donate a kidney, thanks to a change in national policy.
Better prevention of Type II diabetes could save both lives and money. The U.S. spends over $730 billion a year — nearly a third of all health care spending — on treating preventable diseases like diabetes.
A drug in clinical trials as a treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) works with a one-two punch that shuts down triglyceride production and fatty acid synthesis in liver cells, UT Southwestern Medical Center researchers show in a new study.
Ochsner Digital Medicine has partnered with Humana Healthy Horizons to provide digital medicine services to its members.
Research by Cleveland Clinic and three other U.S. medical centers has found that bariatric surgery provides better long-term control of blood glucose levels in patients with obesity and type 2 diabetes, compared with medical therapy.
The screenings program wants to identify patients who are at risk of developing diabetes and connect them with resources that can help them manage their condition. The initiative aligns with the broader goal of integrating diabetes testing into routine screenings across dental clinics in our community.
Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to
About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced “beta”) in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It’s not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental factors such as viral infections may trigger the onset of T1D, others suggest genetics may also play some role. Groundbreaking research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of T1D. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.
Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers removed receptors for this hormone from mouse kidneys, the animals developed symptoms akin to chronic kidney disease (CKD).
Diabetic patients who take anti-diabetic drugs - known as glitazones – long term had a lower risk of primary and secondary brain cancer compared with diabetic patients on other medications, new research led by the University of Bristol has found.
Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.
Health care providers who treat diabetes need to think beyond the clinical numbers, such as solely focusing on a person’s glucose goals.
Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.
Melatonin treatment does not affect the insulin resistance or the glucose tolerance of night shift workers, according to a new study from the University of Surrey and the University Medical Centre Hamburg. Melatonin treatment does, however, significantly improve the sleep quality of those working shifts.
UMass Amherst researcher co-leads worldwide efforts to understand how genetic variants are linked with disease to develop new drugs and treatments.
A team of international scientists has developed a more effective treatment for chronic wounds that does not involve antibiotics or silver-based dressings, but an ionized gas called plasma.
Diabetes care providers should account for impacts caused by financial insecurity, researchers suggest
Below are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.
Adults who have obesity and Type 2 diabetes are much more likely to see their diabetes stay in remission if they undergo gastric bypass surgery rather than sleeve gastrectomy, even after regaining weight, according to a study published in the Journal of the American College of Surgeons (JACS).
Cambiar de una dieta poco saludable y un estilo de vida sedentario a una alimentación saludable y ejercicios puede ser abrumador.
Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.
Ozempic and Wegovy, which both contain the active ingredient semaglutide, have received recent attention in the media and on social platforms for its effectiveness in supporting weight loss. Ozempic, which is approved for people with Type 2 diabetes, has now become a widely accepted choice for weight loss, and Wegovy was approved in 2021 for long-term weight management.
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