Focus: Hidden - Ohio

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Study in journal Nature Medicine demonstrates, for the first time, that glioblastoma (GBM) is driven by two distinct subsets of cancer stem cells. Moreover, each subtype of glioma stem cells is driven by distinct transcriptional programs for growth and treatment resistance, and these different cell populations correspond to well-known morphological differences within the GBM itself. More importantly, the researchers found that while chemotherapeutic agents targeting each subtype achieve modest efficacy alone, they are synergistic when combined as demonstrated in a mouse model.

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Farsighted preschoolers and kindergartners have a harder time paying attention and that could put them at risk of slipping behind in school, a new study suggests.

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For the first time, researchers have evidence of exactly what dads are doing while moms are taking care of housework or tending to their child. The results will be disappointing for those who expected more gender equity in modern society.

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Streamlining investigations and prosecutions of opiate dealers is goal of three-year U.S. Department of Justice-funded research

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Building on its national reputation in the performing arts, Baldwin Wallace University has added a dance and movement emphasis to its major in theatre.

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The men who were tried for their role in the 1994 Rwandan genocide that killed up to 1 million people want you to know that they’re actually very good people. That’s the most common way accused men try to account for their actions in testimony before the International Criminal Tribunal for Rwanda, a new study has found.

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Scientists have determined that fungus may play a key role in chronic intestinal inflammation disorders. They found that patients with Crohn’s disease tend to have much higher levels of the fungus Candida tropicalis compared to their healthy family members. A new review published in Digestive and Liver Disease looks at these findings and provides insights into potential new therapeutic approaches using antifungals and probiotics in the treatment of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD).

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ProMedica Toledo Hospital is the first in Ohio to acquire BrightMatter™ technology, an innovative solution that combines advanced imaging, planning, navigation and robotics for complex brain tumor and spinal surgery.

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In conjunction with the release of the film “Battle of the Sexes,” Bowling Green State University sport management professor Nancy Spencer is available to share her experience serving as a line judge for the famed 1973 tennis match between Billie Jean King and Bobby Riggs.

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One of the tactics that discourages student cheating may not work as well in courses that college students particularly dislike, a new study has found.

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Two-day national event in Louisville, Kentucky Oct. 9-10 hosted by The Root Cause Coalition focusing on “how” communities and organizations can address basic needs to improve community and individual health and well-being.

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In the journal Nature Physics, researchers report taking a first step toward controlling electrons’ behavior inside matter—and thus the first step down a long and complicated road that could eventually lead to the ability to create new states of matter at will.

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With a DOE grant, two professors will create a new investment tool to manage risk and catalyze funding at critical stages for energy companies

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Early research results suggest scientists might be on to a way to preserve heart function after heart attacks or for people with inherited heart defects called congenital cardiomyopathies. Researchers at the Cincinnati Children’s Heart Institute report Sept. 28 in Nature Communications that after simulating heart injury in laboratory mouse models, they stopped or slowed cardiac fibrosis, organ enlargement and preserved heart function by blocking a well-known molecular pathway.

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A Case Western Reserve University researcher has turned the origami she enjoyed as a child into a patent-pending soft robot that may one day be used on an assembly line, in surgery or even outer space.

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Like its Egyptian namesake, The Walmart Book of the Dead contains spells and illustrations (albeit as descriptive passages), using them to craft a loose narrative in short chapters centered around a different character; there's a shoplifter, circuit court judge, hustler and, of course, a greeter.

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A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types.

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With a new $5.5 million, five-year federal grant, a Case Western Reserve University researcher is leading an international team to develop functional materials inspired by some of the most desirable substances found in nature. The bioinspired materials produced in the project will be tested in soft-sided robots, but are expected to have a wide range of practical uses.

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ProMedica, an Ohio-based health system, recently held a ribbon cutting ceremony to celebrate the opening of ProMedica Headquarters in downtown Toledo. It marked the end of three and half years of planning and construction to consolidate approximately 1,000 system employees from more than 25 buildings on a single campus.

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ProMedica, an Ohio-based health system, recently held a ribbon cutting ceremony to celebrate the opening of ProMedica Headquarters in downtown Toledo. It marked the end of three and half years of planning and construction to consolidate approximately 1,000 system employees from more than 25 buildings on a single campus.

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When the government gives citizens a personal stake in forested land, trees don’t disappear as quickly and environmental harm slows down.

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Researchers in the United States and Germany have just discovered a previously overlooked part of protein molecules that could be key to how proteins interact with each other inside living cells to carry out specialized functions.

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When it comes to male reproductive fertility, timing is everything. Now scientists are finding new details on how disruption of this timing may contribute to male infertility or congenital illness.

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People who tend to trust their intuition or to believe that the facts they hear are politically biased are more likely to stand behind inaccurate beliefs, a new study suggests.

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With geographic barriers limiting treatment options for many people with multiple sclerosis (MS) , a Case Western Reserve University researcher will use a new $4.9 million award to test online- and teleconference-based adaptations of methods that reduce fatigue and improve quality of life when delivered in person.

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Paramount has signed an agreement to acquire Indiana-based dental benefit provider Dental Health Options by Health Resources, Inc. (HRI).

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CVS Pharmacy and ProMedica will work together to ensure patients experience a seamless transition of care.

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Waking up in the morning with the joint pain, swelling and stiffness that accompanies lupus doesn’t exactly inspire a workout. But research in mice and a related pilot study in humans are showing how regular activity and stress reduction could lead to better health in the long run.

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University Hospitals clinicians are the first in Northeast Ohio to have access to the Community Health Record through CliniSync’s single sign on technology, making access to critical information from other health care facilities more efficient and timely than ever before.

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Feeling the pain of failure leads to more effort to correct your mistake than simply thinking about what went wrong, according to a new study.

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Ethnic restaurants like to brag about how “authentic” they are. But when it comes to the language on their menus, a new study suggests authenticity may not be a hit with some customers.

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Racial housing segregation had some unexpected relationships with how long both blacks and whites lived historically in the United States, a new study suggests.

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Kurt Lu, MD, assistant professor of dermatology at Case Western Reserve University School of Medicine, has received a five year, $3.9 million grant from the National Institutes of Health to expand countermeasures against chemical threats, including mustard gas and mustard-related compounds. The molecular action of mustard on DNA leads to strand breaks and eventual cell death. The goal of the grant is to augment the body’s immune system after exposure, reducing skin swelling and pain as well as enhancing tissue repair.

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With $1.8 million in new funding, Case Western Reserve Professor Mark Joseph, and his colleagues are leading an effort to learn how mixed-income development might more effectively promote social equity and inclusion—as initially intended.

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The Russian government has persuaded many of its citizens to avoid websites and social media platforms that are critical of the government, a new study has found.

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Martha Sajatovic, MD, Professor of Psychiatry and of Neurology at Case Western Reserve University School of Medicine, Willard Brown Chair in Neurological Outcomes Research and Director of the Neurological and Behavioral Outcomes Research Center at University Hospitals Cleveland Medical Center, is the recent recipient of two major research grants.

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It was dark as night during the recent total solar eclipse, yet people and objects were easier to see than on a typical moonless night. Scientists at The Ohio State University have discovered a possible biological explanation – the presence (or absence) of a protein in the retina known as a GABA receptor.

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Biomedical engineering researchers at Case Western Reserve University are refining more than 15 years of work on an electrical nerve-block implant, focusing their next step on new applications related to treating asthma and heart failure.

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The Wood County Health District contracted with Bowling Green State University to assist in its mosquito surveillance project after receiving a $17,696 grant from the Ohio Environmental Protection Agency to study mosquitoes. Dr. Dan Pavuk and two undergraduate biology students have been working on the project all summer.

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A new Bowling Green State University study aims to provide information and guidance to help communities and even major airports get and keep passenger routes. The project will develop research into the use of incentives by airports and communities to attract and retain air service.

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Doctors believe there is some good to be found in nicotine, the highly addictive drug in tobacco products. Lung experts at The Ohio State University Wexner Medical Center are testing whether nicotine can help people with a chronic inflammatory lung disease called sarcoidosis.

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After Hurricane Katrina devastated New Orleans a dozen years ago, there was a sharp and immediate drop in personal debt among residents living in city’s most flooded blocks, according to a new analysis.

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Nicole Steinmetz, PhD, Associate Professor of Biomedical Engineering, Radiology, member of the Case Comprehensive Cancer Center and the Center for RNA Science and Therapeutics in the Division of General Medical Sciences at Case Western Reserve University School of Medicine and the holder of the George J. Picha Designated Professor in Biomaterials, has received a major grant from the National Institutes of Health to help understand how a virus-like particle from plants stimulates potent anti-tumor responses. Under the grant, Steinmetz and colleagues will further test a tiny nanoparticle-based therapeutic that her team developed which targets the body’s own cancer immunity cycle.

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Scientists have found distinctive portions of genetic material—known as lncRNAs—that help sperm develop. Male mice lacking a particular lncRNA have low sperm count, suggesting lncRNAs could represent novel infertility drug targets.

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The first new national guidelines since 2004 on identifying and treating high blood pressure in children and adolescents (aged 3-18 years old) have been published by the American Academy of Pediatrics (AAP), which convened a panel of experts to produce the new recommendations. The AAP report, Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents, offers a series of evidence-based recommendations for pediatricians derived from a comprehensive review of nearly 15,000 medical studies published since 2004.

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The notion that young females limit their own progress based on what they believe about their intelligence—called the “bright girl effect”—does not persist into adulthood, according to new research from Case Western Reserve University.

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People who claim they “don’t see race” when they evaluate others may think they all have similar beliefs about racial justice – but they’re very wrong, according to a new book. In fact, the belief in “racial colorblindness” unites people who range from liberal to conservative and hardened racists to egalitarians.

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In a new study, researchers at The Ohio State University estimate algal blooms at two Ohio lakes cost Ohio homeowners $152 million in lost property value over six years. Meanwhile, a related study suggests that algae is driving anglers away from Lake Erie, causing fishing license sales to drop at least 10 percent every time a bloom reaches a moderate level of health risk.

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The spread of influenza among pigs is common at fairs and other gatherings, and protective measures including cutting the length of time pigs and people congregate make good sense for both the animals and humans, say the authors of a new study.