Dana-Farber Cancer Institute scientists report a number of patients in a small study with RAS-driven lung, ovarian, and thyroid cancers got long-term clinical benefit from a combination of two drugs that targeted molecular pathways controlled by the RAS gene.
New Dana-Farber study shows patients with platinum resistant ovarian cancer who wouldn’t be expected to respond to a PARP inhibitor had partial shrinkage of their tumor with the addition of a kinase inhibitor.
Whitehead Institute scientists have identified a gene that could help clinicians discern which patients have aggressive forms of early stage breast cancer, which could prevent hundreds of thousands of women from undergoing unnecessary treatment and save millions of dollars.
New research suggests that some patients with head and neck cancers can benefit by continuing treatment with an immunotherapy drug after their tumors show signs of enlargement according to investigators at Dana-Farber Cancer Institute and other organizations.
Olin College of Engineering Professor Lynn Andrea Stein, Ph.D., who also serves as special advisor to the provost, was one of only 46 people selected nationally from nominations by college and university presidents or chancellors as a 2017-18 ACE fellow.
The number of older adults who are self-employed outweighs that of young adults, suggesting that people of 50 years and older still have a significant role to play in economies around the world—this according to a new Global Entrepreneurship Monitor (GEM) Special Report on Senior Entrepreneurship.
Blind tadpoles were able to process visual information from eyes grafted onto their tails after being treated with a small molecule neurotransmitter drug that augmented innervation, integration, and function of the transplanted organs. The work, which used a pharmacological reagent already approved for use in humans, provides a potential road map for promoting innervation – the supply of nerves to a body part – in regenerative medicine.
HMX Fundamentals offers four rigorous courses in foundational subjects, including physiology, immunology, biochemistry and genetics. The program is suited for future clinicians and scientifically curious adults seeking in-depth medical knowledge. The program is accepting applications through May 30 for its inaugural summer course.
David M. Livingston, MD, of Dana-Farber Cancer Institute, has won a major award for discoveries in cancer research from the American Association for Cancer Research (AACR).
Judy E. Garber, MD, MPH, director of the Center for Cancer Genetics and Prevention at Dana-Farber Cancer Institute, has been honored by the American Association for Cancer Research (AACR) for outstanding achievement in clinical cancer research.
Entrepreneur and international business leader Harry Susilo has been honored by Babson College with induction into the Academy of Distinguished Entrepreneurs® (ADE) during ceremonies at Babson Connect: Worldwide Entrepreneurial Summit in Thailand on March 25, 2017.
Chee Chew, vice president of consumer engagement at Amazon, has been named to the Board of Trustees at Olin College.
The body’s ability to repair DNA damage declines with age, which causes gradual cell demise, overall bodily degeneration and greater susceptibility to cancer.
David Abdow has been named Dean of Babson Executive and Enterprise Education (BEEE). Abdow comes to Babson from Northeastern University’s D’Amore-Mckim School of Business, where he served as Associate Dean for Executive Programs.
The brains of those who are born blind make new connections in the absence of visual information, resulting in enhanced, compensatory abilities such as a heightened sense of hearing, smell and touch, as well as cognitive functions (such as memory and language) according to a new study led by Massachusetts Eye and Ear researchers.
The Lewis Institute 2017 Community Changemaker Award at Babson College, designed to recognize persons who have set something in motion in order to create positive change, will be presented to Roshni Nadar Malhotra, Executive Director and CEO of HCL Corporation; Director of HCL Technologies; and Trustee of Shiv Nadar Foundation, during ceremonies at Babson Connect Worldwide on Saturday, March 25, 2017 in Bangkok, Thailand.
Dana-Farber Cancer Institute and Lifespan leadership are creating a strategic alliance to advance cancer treatment and research.
A summary of a select abstracts by Dana-Farber researchers being presented at 2017 AACR Annual Meeting in April
Researchers at Beth Israel Deaconess Medical Center (BIDMC) have gained new insight into the genetic and neuronal circuit mechanisms that may contribute to impaired sociability in some forms of Autism Spectrum Disorder.
Pancreatic cancer has the lowest survival rate among all major cancers, largely because physicians lack diagnostic tools to detect the disease in its early, treatable stages. Now, a team of investigators led by Lev T. Perelman, PhD, Director of the Center for Advanced Biomedical Imaging and Photonics at Beth Israel Deaconess Medical Center (BIDMC), has developed a promising new tool capable of distinguishing between harmless pancreatic cysts and those with malignant potential with an overall accuracy of 95 percent. The team’s preliminary data was published online today in the journal Nature Biomedical Engineering.
At a glance: Hospitalized patients treated by higher-spending physicians do not have better outcomes than patients treated by lower-spending physicians. Health care spending varies more across individual physicians than across hospitals. While other studies have examined differences in spending and patient outcomes across geographic regions and across hospitals, this is the first study to analyze the link between spending patterns of individual physicians within the same hospital and patient outcomes.
Depressed patients with chronic rhinosinusitis (CRS) are more likely to miss days of work or school than those without depression symptoms, according to the results of a new study led by the Sinus Center at Massachusetts Eye and Ear.
F.W Olin Graduate School of Business CAM – Accelerate program will be held at the Babson Boston campus and will prepare students for a wide range of career paths
In a new study in the journal Nature, Dana-Farber Cancer Institute scientists report that a compound able to reverse the allegiance of innate immune system cells – turning them from tumor enablers into tumor opponents – caused breast tumors in mice to shrink and withdraw from distant metastases.
Using red blood cells modified to carry disease-specific antigens, scientists from Whitehead Institute and Boston Children’s Hospital have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.
Higher intake of foods containing isoflavones, estrogen-like compounds primarily found in soy, is associated with reduced all-cause mortality in women with hormone-receptor-negative breast cancer and women not treated with hormone therapy as part of cancer treatment.
Two weeks of voluntary wheel running induced higher expression of irisin—a fat-burning hormone released during exercise—in bone tissue in mice. In addition, systemic administration of irisin increased bone formation and thickness, mimicking the effects of exercise on the mouse skeletal system.
• Triple-negative breast cancer quickly becomes resistant to current therapies, leaving patients no therapeutic options. • BIDMC researchers discovered that TNBC cells increase production of pyrimidine nucleotides in response to traditional chemotherapy. • Discovery represents a vulnerability that can be exploited by blocking pyrimidine using an existing inhibitor in combination with chemotherapy.
A new systematic review and meta-analysis finds that lowering the cost of healthy foods significantly increases their consumption, while raising the cost of unhealthy items significantly reduces their intake.
Local study suggests urban mobile clinics may help boost patient participation, engagement in care
A new study suggests that civic engagement, in the form of community-based “Change Clubs,” engages Black/African American women to address nutrition and exercise concerns in their community and motivates them to change their individual behaviors, which may improve heart health.
In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.
Researchers at Whitehead Institute have now uncovered a role for the protein-folding chaperone HSP90 in humans, not only as a modifier of the effects of mutations, but as a mediator of the impact of the environment on the function of mutant proteins. And these effects of HSP90 can alter the course of human diseases.
Hello® Products founder Craig Dubitsky joins Babson College as Entrepreneur in Residence (EIR) at the Arthur M. Blank Center for Entrepreneurship.
Sleep remains an enduring biological mystery with major clinical relevance, according to a review by clinician-researcher Thomas Scammell, MD, of Beth Israel Deaconess Medical Center (BIDMC) and colleagues. In recent decades, new technologies have allowed neuroscientists to identify multiple brain circuits that govern the sleep/wake cycle, as well as the factors that can influence it, such as caffeine and light. But the brain’s complexity is still a stumbling block in understanding this ubiquitous and necessary animal behavior, the researchers wrote. Their review appeared today in the journal Neuron.
David Reich, professor of genetics at Harvard Medical School, has been named co-recipient of the 2017 Dan David Prize in archaeology and natural sciences.
In 2013, Mass. Eye and Ear researchers restored partial hearing to mice by regenerating hair cells — tiny, sound-sensing cells in the ear, which are lost through noise damage, age, etc., and do not regenerate on their own — by converting stem cells found in the ear into hair cells. However, the success of restoring hearing through this approach was limited by the small number of cells that could be turned into hair cells. In a new study in Cell Reports, a research team from Mass. Eye and Ear, Brigham and Women's Hospital and MIT has shown that they can augment the number of those cells, and then convert that large population into hair cells, lending hope that full hearing can be restored to those with hearing loss due to damaged hair cells.
Wellesley College will convene two panels of international leaders and experts for a public forum on the global refugee crisis and its many sociopolitical and geopolitical ramifications, beginning with a keynote from Former Secretary of State Madeleine K. Albright ’59.
As public health officials warn that spring’s warmer temperatures may herald another increase of Zika virus infections in the Caribbean and North and South America, researchers around the world are racing to develop safe and effective measures to prevent the disease. In a review paper published today in the journal Immunity, a group of leading vaccine scientists – including Dan H. Barouch, MD, PhD, of Beth Israel Deaconess Medical Center (BIDMC) – outline advances in the hunt for a Zika vaccine and the challenges that still lie ahead. “The pace of preclinical and early clinical development for Zika vaccines is unprecedented,” said Barouch, corresponding author and director of the Center for Virology and Vaccine Research at BIDMC. “In less than a year, our group and others have demonstrated that multiple vaccine platforms can provide robust protection against Zika virus challenge in animal models. However, unique challenges will need to be addressed in the clinical development of a Zi
Suzanne Olbricht, MD, an accomplished clinician, researcher, educator and health care administrator, has joined Beth Israel Deaconess Medical Center (BIDMC) as Chief of Dermatology.
A new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis (UC), an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the colon. The study was published in the February issue of the journal Clinical Gastroenterology and Hepatology.
Harvard Medical School researchers have successfully “listened in” on the crosstalk between gut microbes and the immune system.
At a glance: New research shows great variation among clinicians’ opioid prescribing practices and links physician prescription patterns to patients’ risk for subsequent long-term opioid use. Being treated by an emergency room physician who prescribes opioids more frequently increases a patient’s risk of long-term opioid use and other adverse outcomes. The results suggest that differences in clinicians’ prescribing habits may be helping to fuel the opioid epidemic sweeping the United States.
Scientists at Joslin Diabetes Center now have identified a route by which fat also can deliver a form of small RNAs called microRNAs that helps to regulate other organs. This mechanism may offer the potential to develop an entirely new therapeutic approach.
Clinical decision-making and treatment choice is a complex cognitive process influenced by multiple variables.
Babson College women’s basketball coach Judy Blinstrub will be honored Wednesday, February 15, 2017, for her legacy of campus leadership that culminated in her 600th career victory last week.
Joslin Diabetes Center will take part in two clinical trials this year to test artificial pancreas systems designed to automatically monitor and regulate blood glucose levels in people with type 1 diabetes, which would replace traditional methods of managing the disease such as testing blood glucose levels by finger stick or using continuous glucose monitoring systems with separate, non-integrated delivery of insulin by either injections or a pump.
Babson College has introduced a new part-time Master of Science in Business Analytics (MSBA) program, and will begin enrolling students for the fall of 2017.
Babson College Professor Heidi Neck has co-authored the latest in entrepreneurship education books rooted in Babson methodology — Entrepreneurship: The Practice and Mindset.
Carolina Pina—entrepreneur, advisor, and philanthropist, has been named Director of Babson College’s Women Innovating Now (WIN) Lab® Miami.
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