In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
This phenomenon generates like a tail or a head of hair giving it the appearance of a giant comet. Already observed in some very large and very hot exoplanets, this phenomenon is viewed for the first time with such a magnitude. The cloud might explain the formation of some hot and rocky super-Earths. It would also be an indicator for detecting extrasolar oceans. Finally, it would be used to envisage the future of our atmosphere. These results are published in the latest edition of the journal Nature.
A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer, potentially at a stage amenable to surgical treatment, according to a study at The University of Texas MD Anderson Cancer Center.
A progress article published June 23 in the journal Nature Materials describes recent developments and predicts future advances in phonon wave interference and thermal bandgap materials -- approaches to controlling heat transfer.
A progress article published June 23 in the journal Nature Materials describes recent developments and predicts future advances in phonon wave interference and thermal bandgap materials -- approaches to controlling heat transfer.
New technique developed by Brookhaven Lab scientists to rapidly create multi-layered, self-assembled grids could transform the manufacture of high-tech coatings for anti-reflective surfaces, improved solar cells, and touchscreen electronics.
Using optogenetics, researchers have established a new approach for pacing the heart and synchronizing its mechanical activity without a conventional electrical pacemaker. Could help avoid many drawbacks of electrical pacemakers.
In 1999 Danish scientist Per Bak made the startling proposal that the brain remained stable for much the same reason a sand pile does; many small avalanches hold it at a balance point, where --in the brain's case -- information processing is optimized. Now scientists have showed for the first time that a brain receiving and processing sensory input follows these dynamics.
The new study, co-led by Howard Hughes Medical Institute (HHMI) investigator David Reich at Harvard Medical School and Svante Pääbo at the Max Planck Institute in Germany, provides the first genetic evidence that humans interbred with Neanderthals in Europe.
Regenerative medicine researchers at UT Southwestern Medical Center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.
Scientists built nanoscale mirrors to trap light around atoms inside of diamond crystals. The mirrored cavities allow light to bounce back and forth up to 10,000 times, enhancing the normally weak interaction between light and the electronic spin states in the atoms. As a result, a 200-microsecond spin-coherence time was produced. The enhanced interactions and extended spin-coherence times are essential steps toward realizing quantum computing systems to solve some problems faster than conventional systems.
Using X-rays, scientists measured the ultrafast response of DNA nucleobases to UV light. They found that the UV excited state in the nucleobase thymine decays rapidly, harmlessly dissipating the potentially destructive UV energy. The findings give new insight on how the nucleobases inside DNA protect themselves from light-induced damage.
A quantum mechanical transport phenomenon demonstrated for the first time in synthetic, atomically-thin layered material at room temperature could lead to novel nanoelectronic circuits and devices, according to researchers at Penn State and three other U.S. and international universities.
After collecting data on a leukemia-affected family for nearly a decade, Children’s Hospital of Michigan, Detroit Medical Center (DMC), Hematologist and Wayne State University School of Medicine Professor of Pediatrics Madhvi Rajpurkar, M.D., joined an international team of genetic researchers in an effort to track down a mutation partly responsible for causing the disease. Their findings, recently published in one of the world’s leading science journals, have “major implications” for better understanding the genetic basis of several types of cancer, including leukemia.
By manipulating the activity of Activin receptors in the brain, researchers were able to increase or decrease cocaine-taking and relapse behavior in animal models. The study focused on receptors in regions of the brain involved in pleasure and reward.
A team of University of Washington researchers has identified a mechanism that some plant cells use to receive complex and contradictory messages from their neighbors.
For the first time, researchers have shown that a dissociation pathway called roaming radical dynamics is a possibility for not just simple, single molecule reactions but more complex, multiple molecule, or bimolecular, reactions.
In a study that could improve the safety of next-generation batteries, researchers discovered that adding two chemicals to the electrolyte of a lithium metal battery prevents the formation of dendrites – “fingers” of lithium that pierce the barrier between the battery’s halves, causing it to short out, overheat and sometimes burst into flame.
A team of researchers led by Yu-Hua Tseng, Ph.D., Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, has created cell lines of human brown and white fat precursor cells that will help investigators to pick apart the factors that drive the development and activity of each type of cell.
A major international study finds that surprisingly few bee species are responsible for pollinating the planet's crops: only two percent of wild bee species pollinate 80 percent of bee-pollinated crops worldwide.
Researchers from the Johns Hopkins Bloomberg School of Public Health have located a new – and likely more promising, they say – target for a potential vaccine against malaria, a mosquito-borne illness that kills as many as 750,000 people each year.
They’re pesky and annoying when they get into your fruit, but Drosophila melanogaster, more affectionately known as the “fruit fly,” have led researchers at Florida Atlantic University to an unexpected discovery involving drowning and comas.
Scientists have observed, in metals for the first time, transient excitons – the primary response of free electrons to light. Detecting excitons in metals could provide clues on how light is turned into energy in solar cells and plants.
Challenging previously held views, scientific results show that californium can covalently bond with borate, dramatically altering the electronic characteristics of the californium ion. This research may show how to further optimize nuclear reactor fuel processes.
A research team has realized one of the long-standing theoretical predictions in nonlinear optical metamaterials: creation of a nonlinear material that has opposite refractive indices at the fundamental and harmonic frequencies of light.
Researchers have found the genetic ‘needles in a haystack’ to gain the first hints at how diatoms — tiny drifting algae that carry out a large part of Earth’s photosynthesis — detect and respond to increasing carbon dioxide in the world's oceans.
A research team's discovery of new information about how plants synthesize carotenoids, precursors for vitamin A that are essential for plant development and survival, and human health, could help scientists increase the levels of provitamin A in food crops and reduce global vitamin A deficiency.
A decade of work at Johns Hopkins has yielded a computer formula that predicts which mutations are likely to have the largest effect on the activity of "genetic dimmer switches," suggesting new targets for diagnosis and treatment of many complex diseases.
Led by James Hone’s group at Columbia Engineering, a team of scientists from Columbia, SNU, and KRISS demonstrated—for the first time—an on-chip visible light source using graphene, an atomically thin and perfectly crystalline form of carbon, as a filament. They attached small strips of graphene to metal electrodes, suspended the strips above the substrate, and passed a current through the filaments to cause them to heat up. (Nature Nanotechnology AOP June 15)
Chemists at The Scripps Research Institute have invented the first practical, scalable method for synthesizing jiadifenolide, a plant-derived molecule that may have powerful brain-protecting properties.
Chemists have witnessed atoms of one chemical element morph into another for the first time ever—a feat that produced an unexpected outcome that could lead to a new way to safely treat cancer with radiation.
Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore’s MinIONTM device, a genome sequencer that can fit in the palm of your hand.
Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence.
An experimental drug improves the ability of heart muscle cells damaged by heart failure to pump blood, according to the results of a study led by Icahn School of Medicine at Mount Sinai.
Scientists from the Florida campus of The Scripps Research Institute have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming cells in patients suffering from bone loss.
X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory have for the first time observed an exotic property that could warp the electronic structure of a material in a way that reduces heat buildup and improves performance in ever-smaller computer components.
An international team of scientists has found that the climatic events that ended the ice age before last are surprisingly different to those of the last ice age.
An international team of scientists has found that the climatic events that ended the ice age before last are surprisingly different to those of the last ice age.
A previously unknown link between the immune system and the death of motor neurons in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, has been discovered by scientists at the CHUM Research Centre and the University of Montreal.
The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury’s verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. Cedars-Sinai researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are processed. They show that the activity of these neurons is indicative of the confidence by which a memory will be retrieved.
An upset in the body’s natural balance of gut bacteria that may lead to life-threatening bloodstream infections can be reversed by enhancing a specific immune defense response, UT Southwestern Medical Center researchers have found.
The global movement patterns of all four seasonal influenza viruses are illustrated in research published today in the journal Nature, providing a detailed account of country-to-country virus spread over the last decade and revealing unexpected differences in circulation patterns between viruses.
The results of a recent study on targeted therapy of a specific type of brain cancer were published by Nature Medicine showing specific progress in cancer treatment.
A team of scientists have taken quantum teleportation – a method of communicating information from one location to another without having to physically move it – to a higher level by using certain high-dimensional states (which they dubbed “donut” states) for teleportation. Stony Brook University physicist Tzu-Chieh Wei, PhD, and colleagues nationally demonstrated that their method works, is more reliable than previous teleportation schemes, and could be a stepping stone toward building a quantum communications network. Their findings appear in Nature Communications.
Comprehensive analysis of data from NASA's Hubble Space Telescope shows that two of Pluto's moons, Nix and Hydra, wobble unpredictably. The results appear in the June 4 issue of the journal Nature. To learn even more, join the Hubble Hangout with Pluto scientists at 3pm EDT on Thurs., June 4 by visiting http://hbbl.us/y6E .
Comprehensive analysis of data from NASA's Hubble Space Telescope shows that two of Pluto's moons, Nix and Hydra, wobble unpredictably. The results appear in the June 4 issue of the journal Nature. To learn even more, join the Hubble Hangout with Pluto scientists at 3pm EDT on Thurs., June 4 by visiting http://hbbl.us/y6E .
Phosphore's striking properties a step closer to being used to improve electronic and optoelectronic devices thanks to Polytechnique Montréal and Université de Montréal researchers.
A rare eye disorder marked by color blindness, light sensitivity, and other vision problems can result from a newly discovered gene mutation identified by an international research team, including scientists from Columbia University Medical Center (CUMC). The findings, which were published today in the online edition of Nature Genetics, could lead to new, targeted treatments for this form of color blindness.
People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.