Investigators in the Smidt Heart Institute at Cedars-Sinai and colleagues report that women with Type 2 diabetes diagnosed with hypertension before age 50 may benefit from intensive blood pressure treatment.
Cucumber (Cucumis sativus L.) holds significant importance among greenhouse vegetables in China, despite its relatively low salt tolerance. Grafting cucumber onto pumpkin rootstocks, which exhibit strong salt tolerance, can improve its resistance to saline conditions. Earlier research conducted by the team revealed that the pumpkin rootstock CmoNAC1 boosts salt tolerance in grafted cucumbers by modulating H2O2/ABA signaling and maintaining K+/Na+ balance through its interaction with the promoters of CmoRBOHD1/CmoNCED6 and CmoAKT1;2/CmoHKT1;1.
The frequency and intensity of plant stresses have increased in recent years due to climate change. Among them, low temperature is an unavoidable environmental factor limiting agricultural productivity.
A Ludwig Cancer Research study has discovered how a lipid molecule found at high levels within tumors undermines the anti-cancer immune response and compromises a recently approved immunotherapy known as adoptive cell therapy (ACT) using tumor infiltrating lymphocytes, or TIL-ACT.
Researchers investigated the influence of ploidy level on mitochondrial DNA (mtDNA) copy number and gene expression in fish. They compared mtDNA copy numbers in liver and muscle of red crucian carp, common carp, and two allotriploid fish across different seasons.
Diosgenin, a secondary metabolite isolated from the Dioscorea spp. plant family, is an irreplaceable and ideal starting material for the synthesis of steroid hormone drugs.
In perennial woody plants, bud endodormancy is crucial for survival under adverse environmental conditions in winter such as low temperature (LT) and dehydration stress.
Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in the Annals of Neurology, provide the first concrete data to help doctors counsel those with this condition on their cognitive prognosis, future plans, and potential treatments, the authors said.
Grafting is a traditional and significant strategy to suppress soil-borne diseases, such as the crown gall disease caused by tumorigenic Agrobacterium and Rhizobium.
Pick's disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65.
.Researchers at the Department of Energy’s Oak Ridge National Laboratory developed a comprehensive modeling method to better predict the drop in electricity generation when hurricane clouds overshadow solar panels. The team explored ways to compensate for these energy losses with super grids, a collection of grids connected so electricity can flow across island chains or between continents.
The researchers established the method of monitoring and evaluation of disaster risk caused by linkage failure and instability of residual coal pillar and rock strata in multi-coal seam mining. The method of monitoring and evaluation not only reduce disaster risk in multi-coal seam mining but provide reference value for the disaster caused by the instability of residual coal pillars during the utilization of closed/abandoned mines.
Scientists have developed a new method for enhancing X-ray microscopy experiments by allowing researchers to adjust experiments based on data that is being collected on the fly, potentially paving the way for more autonomous discovery.
Scientists have made the first-ever remote observations of the fine-scale structure at the base of clouds. The results show that the air-cloud interface is a transition zone where aerosol particles suspended in Earth's atmosphere give rise to the droplets that ultimately form clouds.
Franziska Roesner, a University of Washington associate professor, has two papers coming out in May looking at TikTok’s algorithm and its effects on users.
In a ground-breaking first, researchers created scaffolds with enhanced strength by fabricating 20 vol% polydopamine-modified nano hydroxyapatite (pDA-nHA), featuring a distinctive lamellar structure.
Dr. Han’s team (KERI) has significantly improved the stability of anode materials by developing a manufacturing technology for “silicon-nitrogen-doped carbon composite anode materials” Published in a prestigious international academic journal.
As wildfires in Siberia become more common, global climate modeling estimates significant impacts on climate, air quality, health, and economies in East Asia and across the northern hemisphere.
Estuaries — where freshwater rivers meet the salty sea — are great locations for birdwatching and kayaking. In these areas, waters containing different salt concentrations mix and may be sources of sustainable, “blue” osmotic energy. Researchers in ACS Energy Letters report creating a semipermeable membrane that harvests osmotic energy from salt gradients and converts it to electricity. The new design had an output power density more than two times higher than commercial membranes in lab demonstrations.
The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe. Named Naegleriavirus, these belong to the giant viruses, a group known for their unusually large particles and complex genomes.
Perinatal transmission of HIV to newborns is associated with serious cognitive deficits as children grow older, according to a detailed analysis of 35 studies conducted by Georgetown University Medical Center neuroscientists. The finding helps pinpoint the geographic regions and factors that may be important for brain development outcomes related to perinatal HIV infection: mother-to-child HIV transmission during pregnancy, labor and delivery, or breastfeeding.
A recent study designed and implemented by investigators at Cedars-Sinai found that artificial intelligence (AI) can accurately evaluate cardiovascular risk during a routine chest computed tomography (CT) scan without contrast.
استخدم باحثو مايو كلينك نهجًا جديدًا للعلاج الكيميائي لزيادة معدل البقاء على قيد الحياة بأكثر من الضعف لمرضى سرطان المعدة وسرطان الصفاق النَقيلي، وهو السرطان الذي انتشر في بطانة التجويف البطني، وفقًا لدراسة نُشرت في مجلة Annals of Surgical Oncology.
Investigadores de Mayo Clinic han utilizado un nuevo enfoque de la quimioterapia para más que duplicar la tasa de supervivencia típica de los pacientes con cáncer de estómago y metástasis peritoneal, es decir, del cáncer que se ha diseminado al revestimiento de la cavidad abdominal, según un estudio publicado en Anales de Oncología Quirúrgica.
Pesquisadores da Mayo Clinic utilizaram uma nova abordagem à quimioterapia para mais do que dobrar a taxa de sobrevivência típica dos pacientes com câncer de estômago e metástase peritoneal, ou seja, do câncer que se espalhou para o revestimento da cavidade abdominal, de acordo com um estudo publicado nos Anais da Oncologia Cirúrgica.
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UChicago researchers analyzed health information on TikTok to identify trends in video quality — how much misinformation is out there, and does it come from specific sources?
The Wilkes Climate Launch Prize is one of the largest university-affiliate climate awards in the world and is geared to spur innovation and breakthroughs. The prize is specifically calibrated to support unconventional or first-of-a-kind projects that often have difficulty getting funding.
New research from the University of Washington shows the brain’s response to viewing errors in both the syntax (form) and semantics (meaning) of code appeared identical to those that occur when fluent readers process sentences on a word-by-word basis, supporting a resemblance between how people learn computer and natural languages.
At a time when health resources are at a premium and need to be wisely allocated, health professionals must find points within men’s lives when it makes the most sense to intervene and advocate for preventive care for promoting better health outcomes.
Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.
A new study led by researchers at the American Cancer Society (ACS) highlights the lasting financial impact of a cancer diagnosis for many working-age adults and their families in the United States. It shows a cancer diagnosis and the time required for its treatment can result in employment disruptions, loss of household income and loss of employment-based health insurance coverage, leading to financial hardship.
In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC). Published in Clinical Cancer Research, the findings illustrate the potential of siRNA for cancer therapy.
Entanglement has paved the way for enriching our understanding of physics and implementing quantum information technology. Scientists at POSTECH introduce a new type of entanglement: Frequency-domain photon number-path entanglement. Utilizing a frequency beam splitter converting single-photon frequency with a 50% probability, they observe a two-fold enhanced resolution of interference pattern compared to the single-photon counterpart, with unprecedented stability.
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When exposed to stress, people with alcohol use disorder engage parts of the brain associated with both stress and addiction, which may cause them to drink or crave alcohol after a stressful experience, suggest the authors of a study published in Alcohol: Clinical and Experimental Research.
Even subtle differences in the wording of social media messages may be enough to sway young people’s beliefs about depression and anxiety and their treatment. Researchers found that college students were more optimistic about the possibility of successfully treating mental health problems after they read social media messages conveying a “growth mindset.”
The surging need for greater bandwidth in communication networks and advanced optical systems underscores the urgency for efficient, tunable optical materials capable of precise light modulation.
In light of the national opioid crisis, a recent study by researchers at the Rothman Orthopaedic Institute and its Department of Medical Cannabis explores the use of medical cannabis (MC) as a potential alternative for chronic pain management.
Climate scientists and national security experts at Pacific Northwest National Laboratory are working together to explore the security consequences of the changing climate.
A team led by Dr. Jae-Woo Choi of the Water Resource Cycle Research Center at the Korea Institute of Science and Technology (KIST) announced that they have developed a technology that can selectively recover high-purity gold from electrical and electronic waste containing various metals using textile materials.