Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture dishes and decreases inflammation and frailty in aged mice.
Cologuard stool DNA testing for colorectal cancer was found to be an accurate noninvasive screening option for Alaska Native people, a population with one of world’s highest rates of colorectal cancer, concluded researchers from the Alaska Native Tribal Health Consortium and Mayo Clinic.
Colorectal cancer remains the second leading cause of cancer death for men and women combined in the U.S. The goal of screening is to reduce the number of people who die from this common cancer. According to Mayo Clinic cancer experts there are gaps in current screening approaches in terms of detection accuracy, patient willingness to use them, and accessibility.
New research suggests that older women who complain of memory problems may be at higher risk for experiencing diagnosed memory and thinking impairment decades later. The study is published in the October 28, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A blue-ribbon project group funded by the National Institutes of Health has published the first consensus guidelines on how researchers should share genomic findings in research on adults and children with other family members. The recommendations, published in the Journal of Law, Medicine & Ethics, offer direction on sharing information before and after the death of an individual research participant.
Stepping down asthma medicines can be done safely and at less cost for patients says a new Mayo Clinic study published this week in The Journal of Allergy and Clinical Immunology.
Mayo Clinic researchers in Rochester, Minnesota, collaborated with the University of Mississippi Medical Center on a recent study, “Troponin T as a Predictor of End-Stage Renal Disease and All-Cause Death in African-American and Whites From Hypertensive Families.”
Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A newly studied class of water contaminants that is known to be toxic and hormone disrupting to marine animals is present likely due in part to indirect effects of human activity.
A study of people with multiple sclerosis (MS) found that those who spent time in the sun every day during the summer as teens developed the disease later than those reporting not spending time in the sun every day. The study, which was published in the October 7, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology, also found that people who were overweight at age 20 developed the disease earlier than those who were average weight or underweight.
Care at Hand and Wellpepper were selected as winners of the first-ever Mayo Clinic Think Big Challenge, which was sponsored by Mayo Clinic Center for Innovation (CFI), Mayo Clinic Ventures and AVIA Health Innovation. Winners will receive a $50,000 award and one year of consultation to help develop their innovative concepts.
ROCHESTER, Minn. — The genetic makeup of colon cancer tumors and survival rates for patients with the disease differ by race, according to a study from researchers at the Mayo Clinic Cancer Center, published in the October 2015 issue of the Journal of the National Cancer Institute.
Menopause is associated with many bothersome symptoms, including hot flashes, night sweats, sleep disturbances, difficulty with mood, memory or concentration, and changes in sexual function. Mayo Clinic physicians recently released findings from research that demonstrated a connection between the severity of menopausal symptoms and a woman’s recent experience of abuse. The abuse could be verbal or emotional, physical or sexual.
Stroke is very rare in children, but colds, flu and other minor infections may temporarily increase stroke risk in children, according to a study published in the September 30, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found routine childhood vaccines may decrease the risk of stroke.
While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology
The Mayo Practice Transformation Network is one of 39 health care collaborative networks selected to participate in the Transforming Clinical Practice Initiative, announced today by U.S. Department of Health and Human Services Secretary Sylvia M. Burwell. Mayo Clinic will receive up to $9.7 million to provide technical assistance support to help equip clinicians in the Mayo Practice Transformation Network with tools, information and network support needed to improve quality of care, increase patients’ access to information and spend health care dollars more wisely.
Choosing the right antidepressant can be a daunting task. With so many choices and such unpredictability in their individual effects, patients with depression often spend months or years casting about for the right medication, while clinicians are often uneasy or unwilling to offer options other than their preferred prescriptions.
The risk for hospitalization doubles for kids with asthma who are exposed to secondhand smoke, according to a study led by Mayo Clinic Children’s Research Center.
People who get dizzy several minutes after standing up may be at risk of more serious conditions and even an increased risk of death, according to new research published in the September 23, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
How is individualized medicine working? Let us count the ways.
A national team of researchers has developed a first-of-its-kind, 3D-printed guide that helps regrow both the sensory and motor functions of complex nerves after injury.
MINNEAPOLIS – Being overweight or obese may be tied to an increased risk of a type of brain tumor called meningioma, according to a new meta-analysis published in the September 16, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. Meningiomas occur at a rate of about five to eight cases per 100,000 people per year. The five-year survival rate for meningioma is 63 percent.
Mayo Clinic researchers have identified a protein marker whose frequency may predict patient response to PD-1 blockade immunotherapy for melanoma. An abstract of their findings was presented today at the American Association for Cancer Research International Cancer Immunotherapy Conference in New York City.
Researchers on Mayo Clinic’s Florida campus have been awarded a $13.3 million, five-year federal grant to test a vaccine designed to prevent the recurrence of triple-negative breast cancer, a subset of breast cancer for which no there are no targeted therapies.
Researchers may have discovered a new marker found in the blood for episodic migraine, according to a study published in the September 9, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. Episodic migraine is defined as having less than 15 headaches per month.
Low-risk cancers that do not have any symptoms and presumably will not cause problems in the future are responsible for the rapid increase in the number of new cases of thyroid cancer diagnosed over the past decade, according to a Mayo Clinic study published in the journal Thyroid. According to the study authors, nearly one-third of these recent cases were diagnosed when clinicians used high-tech imaging even when no symptoms of thyroid disease were present.
Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.
Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer’s disease, according to a new study published in the September 2, 2015, online version of Neurology®, the medical journal of the American Academy of Neurology.
In the August issue of the Journal of Gastrointestinal Surgery, Mayo Clinic researchers provided a detailed comparison of patient outcomes associated with synchronous and sequential colorectal and liver resections in patients with stage IV colorectal cancer, identifying some benchmarks for surgical practice.
ROCHESTER Minn. — A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Mayo Clinic Cancer Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research.
People who will develop dementia may begin to lose awareness of their memory problems two to three years before the actual onset of the disease, according to a new study published in the August 26, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that several dementia-related brain changes, or pathologies, are associated with the decline in memory awareness.
JACKSONVILLE, Fla. — Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic’s Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
Testing the saliva of healthy older people for the level of the stress hormone cortisol may help identify individuals who should be screened for problems with thinking skills, according to a study published in the August 19, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Modern lifestyle factors, such as texting, reaching for your keyboard or wearing high heels, can create postural stressors that often cause muscle imbalances and injury. Having good posture is essential for good health; however, understanding what good posture is and maintaining it are hard.
Dosing obese teens with vitamin D shows no benefits for their heart health or diabetes risk, and could have the unintended consequences of increasing cholesterol and fat-storing triglycerides. These are the latest findings in a series of Mayo Clinic studies in childhood obesity.
A multicenter study involving Mayo Clinic researchers has found that the National Cancer Institute's Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE), was accurate, reliable and responsive, compared to other, established patient-reported and clinical measures. The study is published today in the journal JAMA Oncology.
A new study suggests children with multiple sclerosis (MS) who exercise regularly may have a less active disease. The research is published in the August 12, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
People with low scores on a test of executive function, the higher-level thinking skills used to reason, problem solve and plan, may be at higher risk of heart attack or stroke, according to a new study published in the August 5, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
With the growing number of people with Alzheimer’s disease, understanding their care is vital for doctors. Yet medical students often just learn the facts and may only see people with advanced disease who are at the hospital or nursing home. A study shows a new way to help medical students learn about the disease—at the art museum.
Hysterectomy may be a marker of early cardiovascular risk and disease, especially in women under 35, according to Mayo Clinic experts.
Mayo Clinic and Raffles Medical Group announced today that Singapore-based Raffles has joined the Mayo Clinic Care Network, a growing network of organizations committed to better serving patients and their families through collaboration.
Mayo Clinic is announcing results of a study on the effectiveness of left-ventricular assist devices (LVAD) in treating patients with a form of cardiomyopathy called restrictive cardiomyopathy (RCM).
New research suggests concussion may not significantly impair symptoms or cognitive skills for one gender over another, however, women may still experience greater symptoms and poorer cognitive performance at preseason testing. The study released today will be presented at the Sports Concussion Conference in Denver, July 24 to 26, hosted by the American Academy of Neurology, the world’s leading authority on diagnosing and managing sports concussion.
New research suggests older people who experience migraines may have an increased risk of stroke, but only if they are smokers. The study is published in the July 22, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic’s Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal.
Methodist Healthcare and Mayo Clinic announced today that Methodist has joined the Mayo Clinic Care Network, a national network of health care providers committed to better serving patients and their families through collaboration.
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