A team led by Tufts University researchers discovered that a communications breakdown between two biochemical pathways is involved in causing cataracts in mice. The newfound relationship between the ubiquitin and calpain pathways may lead to pharmaceuticals and dietary approaches that can prolong the function of the relevant pathways and delay the onset of cataracts in people.
BOSTON – Each year more than 12 million Americans visit their doctors complaining of headaches, which result in lost productivity and costs of upward of $31 billion annually. A new study by researchers from Beth Israel Deaconess Medical Center (BIDMC) suggests some of that cost could be offset by physicians ordering fewer tests and an increased focus on counseling about lifestyle changes.
Dana-Farber researchers report women with small, HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were highly unlikely to have the cancer recur within three years.
Whitehead Institute scientists have for the first time identified a protein that appears to be a nutrient sensor for the key growth-regulating mTORC1 metabolic pathway.
Last September, after years of watching, a team of scientists led by Amherst College astronomy professor Daryl Haggard observed and recorded the largest-ever flare in X-rays from a supermassive black hole at the center of the Milky Way.
In studying the cellular structure and function of insulin, a research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has uncovered previously unknown steps in the development of insulin resistance, a hallmark of type 2 diabetes.
Two new reports from researchers at Tufts University show fast food portion sizes and product formulation, including sodium content and fat, stayed relatively the same between 1996 and 2013. The exception was a consistent decline in trans fat of fries between 2000 and 2009. Nevertheless, calorie and sodium contents remain high suggesting emphasis needs to be shifted from portion size to additional factors such as total calories and number of items ordered.
Immunotherapy, genomic profiling, and investigating game-changing drug therapies topped the list of most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014.
The American Diabetes Association announced today that they are lowering the Body Mass Index (BMI) cut point for which they recommend screening Asian Americans for type 2 diabetes.
Wellesley College welcomes former Secretary of State and Class of 1959 alumna Madeleine Korbel Albright back to campus for the 2015 Albright Institute Wintersession. On January 22, 2015, Secretary Albright joins Elizabeth Cousens, U.S. Representative on the UN Economic and Social Council and Alternate Representative to the UN General Assembly, and Dr. Homi Kharas, a Brookings Institution senior fellow and deputy director for the Global Economy and Development program, for a public dialogue on ending poverty and transforming economies through sustainable development.
Scientists from Massachusetts Eye and Ear/Harvard Medical School and Fudan University have shown that blocking the Notch pathway plays an essential role that determines cochlear progenitor cell proliferation capacity.
The Davis Museum at Wellesley College presents Parviz Tanavoli, the first comprehensive retrospective exhibition of the influential Iranian artist’s work to be mounted by a U.S. museum. On view February 10-June 7, the exhibition will survey the breadth and richness of the artist’s career from the 196os to the present day, marking the 50th Anniversary of Tanavoli’s famed ‘Heech’ project.
Parents of children involved in an elementary school-based community intervention to prevent obesity appear to share in its health benefits. A new analysis shows an association between being exposed to the intervention as a parent and a modest decrease in body mass index (BMI) compared to parents in two similar control communities.
In a follow-up to earlier studies of learning in infancy, researchers report that talking to babies in their first year, in particular naming things and people, helps them connect what they see and hear. This learning between 6 and 9 months aids later learning and is evident years later.
Extra vitamin E protected older mice from a bacterial infection that commonly causes pneumonia. The study from researchers at Tufts University found that extra vitamin E helped regulate the mice’s immune system.
In a study published today by Nature, researchers at Joslin Diabetes Center used a microscopic worm (C. elegans) to identify a new path that could lead to drugs to slow aging and the chronic diseases that often accompany it—and might even lead to better cosmetics.
A new retrospective study by epidemiologists at Tufts finds significant geographic disparities in HIV and hepatitis C related mortality in Massachusetts from 2002-2011. The study, published in PLOS ONE, used geospatial techniques to identify hotspots and coldspots in the state.
New optical diagnostic technology developed at Tufts University School of Engineering promises new ways to identify and monitor brain damage resulting from traumatic injury, stroke or vascular dementia—in real time and without invasive procedures.
Many people with multiple sclerosis have trouble with balance and a fear of falling, which can negatively affects quality of life. A new study funded by the National MS Society will look at how sensation in the feet relates to balance and whether vibrating insoles might aid walking and balance.
Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy.
New 3D numerical modeling that captures far more geometric complexity of an active fault segment in southern California than any other, suggests that the overall earthquake hazard for towns on the west side of the Coachella Valley such as Palm Springs may be slightly lower than previously believed.
The Institute for Hepatobiliary and Pancreatic Surgery at Beth Israel Deaconess Medical Center (BIDMC) led by A. James Moser, MD, FACS, will benefit from a $100,000 grant from the Alliance of Families Fighting Pancreatic Cancer (AFFPC).
Babson College Professor of Film Julie Levinson has edited the new book Alexander Payne: Interviews (Conversations with Filmmakers Series), published by the University Press of Mississippi.
Babson College rhetoric instructor Michael Gerhard Martin has authored Easiest If I Had A Gun, a heartbreaking and hilarious collection of short stories published by Braddock Avenue Books.
Project will focus on antibody repertoires and B cell diversity to better understand the role of the immune system in cardiovascular disease
Researchers at MIT's Koch Institute and Boston Children’s Hospital describe how a new light-triggered strategy can provide more accurate control over where aptamers accumulate.
Tufts Dental Facilities Serving Individuals with Disabilities, a network of clinics that provides oral health care to adults and children with intellectual, developmental, or acquired disabilities, will be presented with the Gies Award for Outstanding Achievement by an Academic Dental Institution at an event in March.
While numerous studies have shown that the marriage rate among military service members is much higher than civilians of the same age, new research from a sociologist at the University of Massachusetts Amherst has found specific reasons that lead these young men and women to make this important decision.
Scientists have believed that the lengthening of those repeats occur during DNA replication when cells divide or when the cellular DNA repair machinery gets activated. Recently, however, Tufts University researchers have traced expansive repeats to the process called transcription, which is copying the information from DNA into RNA.
Under a new five-year award of up to $50 million, the University of Minnesota and Tufts University will be part of an international partnership of universities to strengthen global workforce development against emerging pandemic threats. Called One Health Workforce (OHW), the work is part of a new United States Agency for International Development (USAID) Emerging Pandemic Threats 2 program, focusing on disease surveillance, training and outbreak response.
George Tsokos, MD, Chief of Rheumatology at Beth Israel Deaconess Medical Center and a national leader in the field of lupus research was honored by both the Lupus Foundation and the American College of Rheumatology with two awards presented at the 2014 ACR Annual Scientific Meeting.
Rohit Kulkarni, M.D., Ph.D., Senior Investigator in the Section on Islet Cell and Regenerative Biology at Joslin Diabetes Center and Associate Professor at Harvard Medical School, coauthored a paper that was published today in Diabetes, which voiced concerns about the increasing difficulty of access to high quality islet cells for diabetes research.
BOSTON – Charles Safran, MD, FACMI, Chief of the Division of Clinical Informatics at Beth Israel Deaconess Medical Center (BIDMC), has received the American College of Medical Informatics’ 2014 Morris F. Collen Award in recognition of his commitment to and achievements in medical informatics.
Treatment with 3TSR antiangiogenic agent is shown to regress tumors and improve effectiveness of chemotherapy in an animal model of ovarian cancer.
Investigators at Massachusetts Eye and Ear reported the development and characterization of a comprehensive genetic test for inherited eye disorders in the online version of the Nature journal Genetics In Medicine today.
Tufts University School of Engineering researchers and collaborators from Texas A&M University have published the first research to use computational modeling to predict and identify the metabolic products of gastrointestinal (GI) tract microorganisms. Understanding these metabolic products, or metabolites, could influence how clinicians diagnose and treat GI diseases, as well as many other metabolic and neurological diseases increasingly associated with compromised GI function.
Immunologist Herman Eisen, founding member of the MIT Center for Cancer Research, died Nov. 2 at age 96. He is perhaps best known for his early work in describing affinity maturation.
Koch Institute faculty member Sangeeta Bhatia has been selected as one of Foreign Policy magazine’s 100 Leading Global Thinkers of 2014 for her work in developing inexpensive and noninvasive diagnostics for the early detection of colon cancer.
By exploiting a unique feature of the tumor microenvironment, scientists identify a novel delivery platform that leads to the inhibition of microRNA activity -- and the control of cancer growth
Boston researchers detail the types of otologic injury suffered by victims of the Boston Marathon bombing and report on the outcomes of patients undergoing otologic treatment in this paper in Otology & Neurology.
Patients choosing cataract surgery at Massachusetts Eye and Ear may now elect to have laser-assisted cataract surgery with the femtosecond LensSx® Laser. The hospital is one of the few in New England to offer the advanced technology, which enables surgeons to more precisely perform cataract surgery aided by a computer-controlled laser.
The entirely student-run Babson Entrepreneurship Forum will be held at the F.W. Olin Graduate School of Business on Friday, November 14. Centered on the theme of “Owning the Future,” more than 25 prominent speakers will be featured in panels, keynotes, and breakouts throughout the day.
In a major advance in the care of patients with leukemia and other blood disorders, physicians at Dana-Farber/Brigham and Women's Cancer Center have begun using Rapid Heme Panel, a high-tech genetic test that provides, within a matter of days, an unprecedented amount of critical information to aid the choice of treatment.
New findings support the possibility that, in the future, small, non-toxic doses of carbon monoxide could be used therapeutically to provide the immune system with an infection-fighting advantage.
Asthma caused or worsened by living near major roadways cost Los Angeles County more than $441 million in 2007 alone, according to a new peer-reviewed article by researchers from the University of Massachusetts Amherst, the University of Southern California and the University of Basel, Switzerland.
Bruce Furie, MD, Chief of the Division of Hemostasis and Thrombosis at Beth Israel Deaconess Medical Center (BIDMC) has been named a 2014 Distinguished Scientist by the American Heart Association.
Astronomers provide data from a new instrument, offering the most precise picture yet of events 4 billion years ago at the centers of distant, dust-cloaked galaxies. Details are in the first scientific paper based on data collected by the large millimeter telescope and its Redshift Search Receiver.
UMass Amherst anthropologist Sonya Atalay has received a major fellowship award to master the endangered Anishinaabemowin language of Native American Ojibwe tribal communities, in order to expand research and understanding of ancient tribal knowledge and practices that are under an increasing threat of becoming lost forever.
Induced neural stem cells (iNSCs) hold promise for therapeutic transplantation, but their potential in this capacity has been limited by failed efforts to maintain such cells in their multi-potent NSC state. Now, Whitehead Institute scientists have created iNSCs that remain in the multi-potent state—without ongoing expression of reprogramming factors. This allows the iNSCs to self-renew repeatedly to generate cells in quantities sufficient for therapy.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right