The spleen, an organ that helps the body fight infections, might also be a source of the cells that end up doing more harm than good at the site of a spinal cord injury, new research suggests.
If researchers could determine how to send signals to cells responding to a spinal cord injury, they might be able to stop one type of cell from doing additional damage at the injury site and instead, coax it into helping nerve cells grow.
A new study suggests that the handwriting problems that affect children with autism are likely to continue into their teenage years. The research is published in the November 16, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.
Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington's disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin's neuroprotective properties in Huntington's and other neurodegenerative conditions.
A study led by researchers in the Department of Neurosciences at the University of California, San Diego School of Medicine shows unexpected and extensive natural recovery after spinal cord injury in primates. The findings, to be published November 14 in the advance online edition of Nature Neuroscience.
Patients with obstructive sleep apnea (OSA) may blame their daytime difficulties on simple sleepiness, but new research suggests that their brains may be to blame. Specifically, their cognitive challenges may be caused by structural deficits in gray matter, brought on by the intermittent oxygen deprivation that comes with OSA.
Dr. Rosemarie Booze, a top neuroscientist at the University of South Carolina, is conducting NIH-funded research on a phtyoestrogen compound in liquorice root that could prevent the cell death associated with Alzheimer's and other neurodegenerative diseases.
Contrary to earlier research, a new, long-term study suggests that cholesterol level in mid-life may not be linked to later development of Alzheimer’s disease, according to a study published in the November 10, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology. However, the results suggest that large decreases in cholesterol levels in old age could be a better predictor of developing the memory-robbing disease.
High cholesterol levels in middle age do not appear to increase women’s risk of developing Alzheimer’s disease and other forms of dementia later in life, new Johns Hopkins-led research finds, despite a body of scientific evidence long suggesting a link between the two.
New findings by researchers at UT Southwestern Medical Center suggest that serotonin – a brain chemical known to help regulate emotion, mood and sleep – might also have anti-diabetic properties.
The clot-busting drug rt-PA remains the most beneficial proven emergency treatment for strokes caused by blood clots, according to an editorial in the November issue of Archives of Neurology.
UCLA researchers have identified in the mouse the molecular cascade that drives the process of reconnection or sprouting in the adult brain after stroke.
Preschool-aged children who demonstrate fearless behavior also reveal less empathy and more aggression towards their peers. This has been shown in a new study that was carried out at the University of Haifa's Faculty of Education.
Humans can actually regulate the activity of specific neurons in the brain, increasing the firing rate of some while decreasing the rate of others. And study subjects proved this by manipulating an image on a computer screen using only their thoughts.
A new UCLA study published in the Nov. 11 issue of the journal Nature offers insights into a major limitation in the brain's ability to recover function after a stroke and identifies a promising medical therapy to help overcome this limitation.
Researchers from the Columbia University Medical Center and colleagues from the NewYork-Presbyterian/Weill Cornell Medical Center, JFK Johnson Rehabilitation Institute, and Harvard Medical School Department of Physical Medicine and Rehabilitation at the Spaulding Rehabilitation Network have a functional MRI study in the current edition of Neurology. Conventional bedside assessments of consciousness rely on motor responses to indicate awareness and therefore may underestimate capacity for cognition, the researchers say.
Continuing its mission to help neurologists best treat their patients, the American Academy of Neurology has launched Neurology: Clinical Practice, a new medical journal aimed at providing doctors with the latest information on how to improve outcomes for the one in six people affected by a neurologic disorder. The new journal will be sent as a supplement to the November 2, 2010, print issue of Neurology®, the world’s most widely read and highly cited peer-reviewed neurology medical journal.
People admitted to the hospital on a weekend after a stroke are more likely to die compared to people admitted on a weekday, regardless of the severity of the stroke they experience, according to new research published in the November 2, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.
University of Utah (U of U) medical researchers have uncovered a wiring diagram that shows how the brain pays attention to visual, cognitive, sensory, and motor cues. The research provides a critical foundation for the study of abnormalities in attention that can be seen in many brain disorders such as autism, schizophrenia, and attention deficit disorder.
A groundbreaking study on Canadian junior ice hockey uncovers alarming head injury/concussion data and trends that raise many questions about the safety and well being of teenagers and young adults who participate in this popular sport. This is a public health issue that needs to be taken more seriously by players, parents, coaches, and medical professionals. At stake is something more important than winning a game - the present and future health of thousands of young athletes.
Most people have habits that guide them through daily life — for example, their path to work in the morning, or their bedtime routine. The brain patterns that drive this behavior are not well-understood, but a new study from MIT’s McGovern Institute for Brain Research shows that habit formation appears to be an innate ability that is fine-tuned by experience — specifically, the costs and rewards of certain choices.
Scientists are closer to solving one of the many mysteries of multiple sclerosis and other demyelinating diseases, thanks to a recent study conducted at the Salk Institute for Biological Studies. The research revealed a previously unknown connection between two ion channels, which, when misaligned, can cause the many bizarre symptoms that characterize the condition.
Special eye-gaze technology now being used in the Department of Neurology at The Children’s Hospital at Montefiore (CHAM) is revealing the hidden, inner world of children who have Rett Syndrome, a rare and severe autism spectrum disorder that primarily affects little girls.
As anyone who as ever picked up a guitar or a tennis racket knows, precise timing is often an essential part of performing complex tasks. Now, by studying the brain circuits that control bird song, MIT researchers have identified a “chain reaction” of brain activity that appears to control the timing of song.
In a report published in the Oct. 20 issue of Science Translational Medicine, researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center say animal and human data suggest gene therapy to the brain may be able to treat patients with major depression who do not respond to traditional drug treatment.
A dozen new epilepsy drugs are giving doctors and patients more options, but making treatment decisions more complex, a Loyola epilepsy specialist reports in the journal Neurologic Clinics.
For the first time, researchers have discovered a disease mechanism that links hereditary amyotrophic lateral sclerosis and the more common "sporadic" form of ALS -- and points to a possible therapeutic target.
Motherhood may actually cause the brain to grow, not turn it into mush, as some have claimed. Exploratory research found that the brains of new mothers bulked up in areas linked to motivation and behavior.
Chronic depression is an adaptive, reparative neurobiological process gone wrong, say two UC San Diego School of Medicine researchers, positing in a new theory that the debilitating mental state originates from more ancient mechanisms used by the body to deal with physical injury, such as pain, tissue repair and convalescent behavior.
Because of impairments in their insulin sensitivity, obese individuals demonstrate different brain responses than their normal-weight peers while completing a challenging cognitive task, according to new research by psychologists at The University of Texas at Austin.
A new study shows that vitamin B12 may protect against Alzheimer’s disease, adding more evidence to the scientific debate about whether the vitamin is effective in reducing the risk of memory loss. The research will be published in the October 19, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.
In the October 17 issue of Nature Methods, researchers at Thomas Jefferson University describe how they can transfer genes into brain neurons intravenously, using a viral gene delivery vehicle (vector) that causes no side effects.
New research suggests that walking at least six miles per week may protect brain size and in turn, preserve memory in old age, according to a study published in the October 13, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A new study in mouse models by researchers at Columbia University Medical Center has found that the brain’s mitochondria -- the powerhouses of the cell -- are one of the earliest casualties of the disease. The study, which appeared in the online Early Edition of PNAS, also found that impaired mitochondria then injure the neurons’ synapses, which are necessary for normal brain function.
Researchers at the University of California, San Diego School of Medicine, led by Larry R. Squire, PhD, professor of psychiatry, psychology and neurosciences at UC San Diego and a scientist at the VA San Diego Healthcare System, report that working memory of relational information – where an object is located, for example – remains intact even if key brain structures like the hippocampus are damaged.
Women with epilepsy may be more likely to experience infertility, according to new research published in the October 12, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.
For patients with blockages in the carotid artery that supplies blood to the brain, carotid artery stenting (a non-surgical treatment) appears to be associated with an increased risk of both short- and long-term adverse outcomes when compared with surgical treatment (carotid endarterectomy), according to a meta-analysis of previously published studies that was posted online today and will appear in the February 2011 print issue of Archives of Neurology, one of the JAMA/Archives journals.
Insulin resistance, a condition in which insulin produced by the body becomes less effective in reducing blood glucose levels, appears to be associated with an increased risk of stroke in individuals without diabetes, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals.
Researchers at UT Southwestern Medical Center have created an experimental vaccine against beta-amyloid, the small protein that forms plaques in the brain and is believed to contribute to the development of Alzheimer’s disease.
By comparing a clearly defined visual input with the electrical output of the retina, researchers at the Salk Institute for Biological Studies were able to trace for the first time the neuronal circuitry that connects individual photoreceptors with retinal ganglion cells, the neurons that carry visuals signals from the eye to the brain.
A set of proteins found in blood serum shows promise as a sensitive and accurate way to diagnose Alzheimer’s disease, researchers at UT Southwestern Medical Center have found as part of a statewide study.
Patients with a severe traumatic brain injury (and not in shock because of blood loss) who received out-of-hospital administration of hypertonic fluids (a solution with increased concentration of certain electrolytes and thought to help reduce intracranial pressure) as initial resuscitation did not experience better 6-month neurologic outcomes or survival compared to patients who received a normal saline solution, according to a study in the October 6 issue of JAMA.
New research shows how old people are when they first develop Parkinson’s disease is one of many clues in how long they’ll survive with the disease. The research is published in the October 5, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Brain and spinal cord injuries related to all-terrain vehicles (ATVs) appear to be increasing, reports a study in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.
Johns Hopkins scientists have discovered that the over-activation of a single protein may shut down the brain-protecting effects of a molecule and facilitate the most common form of Parkinson’s disease. The finding of this mechanism could lead to important new targets for drugs already known to inhibit it, thus controlling symptoms of the disorder, which affects about 1 million older Americans.
For decades, carefully logging data about how mice go through the motions of their daily routines has been a tedious staple of behavioral and neuroscience research. It’s a task most people would happily cede to automation. Now, according to a new study by MIT neuroscientists, that’s finally possible.
The latest advances in treating neurologic disorders such as stroke, headache, Parkinson's disease, epilepsy and sleep disorders are detailed in a special issue of the journal Neurologic Clinics.