Feature Channels: Stroke and TAVR procedures

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Released: 28-Feb-2022 6:00 AM EST
Non-vitamin K oral anticoagulants versus vitamin K antagonists in post transcatheter aortic valve replacement patients with clinical indication for oral anticoagulation: A meta-analysis
Clinical Cardiology

… TAVR in patients with another indication of OAC, which were published before 28th September 28, 2021. The effectiveness of outcomes was all-cause mortality and stroke … We included 4947 post-TAVR patients with another indication of OAC …

Released: 28-Feb-2022 6:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Background: Stroke associated with transcatheter aortic valve replacement (TAVR) is a potentially devastating complication. Until recently, … of TAVR-related stroke. However, its effectiveness is still undetermined. Objectives: To explore the impact of …

Released: 25-Feb-2022 8:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 24-Feb-2022 7:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 23-Feb-2022 6:55 AM EST
Baseline PA/BSA ratio in patients undergoing transcatheter aortic valve replacement – A novel CT-based marker for the prediction of pulmonary hypertension and outcome
International Journal of Cardiology

… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

Released: 22-Feb-2022 5:00 AM EST
Baseline PA/BSA ratio in patients undergoing transcatheter aortic valve replacement – A novel CT-based marker for the prediction of pulmonary hypertension and outcome
International Journal of Cardiology

… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

Released: 21-Feb-2022 7:00 AM EST
Baseline PA/BSA ratio in patients undergoing transcatheter aortic valve replacement – A novel CT-based marker for the prediction of pulmonary hypertension and outcome
International Journal of Cardiology

… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

Released: 17-Feb-2022 6:00 AM EST
Implication of Different ECG Left Ventricular Hypertrophy in Patients Undergoing Transcatheter Aortic Valve Replacement
Journal of the American Heart Association

… The presence of atrial fibrillation was also included as a risk factor for stroke after TAVR. In these models, ECG LVH by 3 different criteria … patients with severe AS undergoing TAVR to evaluate the association between clinical outcomes after TAVR …

Released: 16-Feb-2022 8:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 15-Feb-2022 9:35 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 14-Feb-2022 8:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 14-Feb-2022 8:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 10-Feb-2022 9:05 AM EST
Comparison of clinical outcomes in elderly patients undergoing TAVR- a nationwide analysis
Preprints

Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to traditional surgical aortic valve replacement (SAVR) that has been increasingly utilized in the management of aortic stenosis. Several studies have compared the outcomes of TAVR to SAVR, and studies have also compared the clinical outcomes in the elderly population. However, the comparison in outcomes of TAVR between patients more than 80 years and less than 80 years old has not been well characterized. Therefore, in this study, we sought to assess the hospital outcomes and major adverse events of TAVR in patients ≥80 years old compared to those <80 years.

Released: 10-Feb-2022 9:05 AM EST
Detecting Usability and User Experience Issues in Stroke Caregiving Apps: An Analysis of User Reviews
Preprints

Existing research has demonstrated the potential of mHealth apps in improving the caregiving outcomes of stroke.

Released: 10-Feb-2022 9:05 AM EST
Disassembly and Mislocalization of AQP4 in Incipient Scar Formation After Experimental Stroke
Preprints

There is an urgent need to better understand the mechanisms involved in scar formation in brain. It is well known that astrocytes are critically engaged in this process. Here we analyze in-cipient scar formation one week after a discrete ischemic insult to the cerebral cortex. We show that the infarct border zone is characterized by pronounced changes in the organization and subcellular localization of the major astrocytic protein AQP4.

Released: 10-Feb-2022 9:00 AM EST
Budget impact analysis of transcatheter aortic valve replacement in low, intermediate, and high-risk patients with severe aortic stenosis in Saudi Arabia
Journal of Medical Economics

… TAVR is associated with higher costs for PPI and budget savings for MDS, AF, and SSI. TAVR also results in savings for non-device costs due … Finally, among high-risk patients, SAVR non-device theatre costs, TAVR monthly maintenance costs …

Released: 10-Feb-2022 9:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 10-Feb-2022 9:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 10-Feb-2022 9:00 AM EST
Infective endocarditis post-transcatheter aortic valve replacement: a systematic review of epidemiology, clinical findings and prognosis
European Heart Journal

… This systematic review aims to evaluate first the incidence of infective endocarditis post TAVR, second … -TAVR, however high mortality and morbidity by means of heart failure and stroke is documented. Ultimately, appropriate medical …

Released: 7-Feb-2022 3:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 7-Feb-2022 3:00 AM EST
Validation of the Valve Academic Research Consortium 3 Technical Success Definition in Patients Undergoing TAVR
Journal of the American College of Cardiology: Cardiovascular Interventions

… Of note, both cardiac and vascular technical failures were independently associated with a 2.6-fold and 1.9-fold increased risk of cardiovascular death and stroke at 1 year following TAVR. This finding underscores the need for further …

Released: 7-Feb-2022 3:00 AM EST
Baseline PA/BSA ratio in patients undergoing transcatheter aortic valve replacement – A novel CT-based marker for the prediction of pulmonary hypertension and outcome
International Journal of Cardiology

… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

Released: 7-Feb-2022 3:00 AM EST
Transcatheter aortic valve replacement in the developing world: Lessons learnt and its implications for practice
Medical Journal Armed Forces India

… In spite of high predilatation rate in our study ischemic stroke occurred only in 1.1% of patents. Contemporary data including different TAVR technologies in high- and intermediate-risk patients show a 30-day stroke rate ranging from 1.4% to 1.9%. To …

Released: 7-Feb-2022 3:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 4-Feb-2022 12:00 PM EST
Overview of FDA Circulatory System Devices Panel virtual meeting on TriGUARD 3 cerebral embolic protection
Catheterization & Cardiovascular Interventions

… TAVR is an important therapy for the treatment of severe symptomatic aortic stenosis. Despite … TAVR technology, periprocedural stroke remains a complication of TAVR and is associated with morbidity and mortality even in younger low-risk …

Released: 4-Feb-2022 12:00 PM EST
Transcatheter Aortic Valve Replacement: Technical Success Remains the Priority
Journal of the American College of Cardiology: Cardiovascular Interventions

… tests noninferiority of TAVR versus surgical aortic valve replacement for a primary endpoint composed of 1-year all-cause mortality, all stroke, and rehospitalization, among women with severe aortic stenosis. Second, patient’s selection remains the …

Released: 1-Feb-2022 1:00 AM EST
The role of TAVR in patients with heart failure: do we have the responses to all questions?
Heart Failure Reviews

… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

Released: 1-Feb-2022 1:00 AM EST
Impact of new-onset versus pre-existing atrial fibrillation on outcomes after transcatheter aortic valve replacement/implantation
IJC Heart & Vasculature

… Specifically, NOAF but not pre-AF is associated with a higher risk of 30-day mortality, stroke, and extended LOS after TAVR/TAVI. … Two studies revealed statistically significant findings concerning the incidence of stroke events in patients …

Released: 1-Feb-2022 1:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 1-Feb-2022 1:00 AM EST
Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement
World Journal of Emergency Medicine

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 1-Feb-2022 1:00 AM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Second, in a study that reported the occurrence of stroke as a primary outcome, it is notable that there is no reporting on the use of neurologic … This device has shown reduced cerebral lesions on radiographic investigation after TAVR, and was …

Released: 24-Jan-2022 4:00 PM EST
Women ages 35 and younger are 44% more likely to have an ischemic stroke than male peers
American Heart Association (AHA)

Women ages 35 years and younger were 44% more likely to have an ischemic stroke (caused by blocked blood vessels in the brain) than their male counterparts, according to a new review of more than a dozen international studies on sex differences in stroke occurrence, published today in a Go Red for Women® 2022 spotlight issue of Stroke, a peer-reviewed journal of the American Stroke Association, a division of the American Heart Association.

Released: 20-Jan-2022 12:55 PM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Second, in a study that reported the occurrence of stroke as a primary outcome, it is notable that there is no reporting on the use of neurologic … This device has shown reduced cerebral lesions on radiographic investigation after TAVR, and was …

Released: 20-Jan-2022 12:55 PM EST
Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement
World Journal of Emergency Medicine

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 19-Jan-2022 10:30 AM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Second, in a study that reported the occurrence of stroke as a primary outcome, it is notable that there is no reporting on the use of neurologic … This device has shown reduced cerebral lesions on radiographic investigation after TAVR, and was …

Released: 19-Jan-2022 10:30 AM EST
Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement
World Journal of Emergency Medicine

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 14-Jan-2022 8:55 AM EST
Management of concomitant coronary artery disease and aortic valve stenosis in the era of transcatheter aortic valve treatment
Mini-invasive Surgery

… patients had a more frequent history of stroke and chronic obstructive pulmonary disease [14] … TAVR is rare and its incidence declines over time after TAVR [65] . Moreover, in this study [66] , the main indication to PCI was acute coronary …

Released: 14-Jan-2022 8:55 AM EST
For TAVR, Home Is Where the Heart Is
Journal of the American College of Cardiology

… replacement (TAVR) … TAVR programs and operators. Because of the large number of TAVRs performed annually and the attendant costs, risk-adjusted, outcomes-based performance measures are critical in fairly comparing care quality …

Released: 14-Jan-2022 8:55 AM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 13-Jan-2022 2:00 AM EST
Asymptomatic Stroke in the Setting of Percutaneous Non-Coronary Intervention Procedures
Medicina

… having significantly reduced the rate of stroke as compared to the first experiences [28], TAVR is still correlated to cerebral complications. … incidence than clinical strokes in patients undergoing aortic valve replacement, and they are …

Released: 11-Jan-2022 2:00 AM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Second, in a study that reported the occurrence of stroke as a primary outcome, it is notable that there is no reporting on the use of neurologic … This device has shown reduced cerebral lesions on radiographic investigation after TAVR, and was …

Released: 11-Jan-2022 2:00 AM EST
Measuring TAVR Prosthesis Gradient Immediately Post-Procedure May Underestimate its Significance
Journal of the American College of Cardiology: Cardiovascular Interventions

… to the increase in stroke volume, and low-flow state alone may not account for the lower gradients immediately post-TAVR. There may be … The importance of the hemodynamic differences between TAVR prostheses on clinical outcomes and …

Released: 11-Jan-2022 2:00 AM EST
Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement
World Journal of Emergency Medicine

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 11-Jan-2022 2:00 AM EST
Safe Recovery After Transcatheter Heart Valve Procedures
Valvular Heart Disease

… One of the most debilitating complications following valve procedures is stroke. Due to the calcific nature of aortic stenosis, stroke occurrence in the setting of TAVR has received the greatest attention. The TVT registry reports the incidence of stroke …

Released: 11-Jan-2022 2:00 AM EST
Prognosis of patients with history of oncological disease undergoing transcatheter aortic valve replacement
Archives of Cardiovascular Diseases Supplements

… OD on one-year outcome following TAVR. … stroke were less prevalent, while chronic kidney disease was more prevalent in comparison with patients with no prior OD. No in-hospital death occurred in patients with prior OD while a trend for higher …

Released: 11-Jan-2022 2:00 AM EST
Impact of chronic obstructive pulmonary disease on one-year outcome after Transcatheter Aortic Valve Replacement
Archives of Cardiovascular Diseases Supplements

… undergoing transcatheter aortic valve replacement (TAVR). … TAVR (median 3 [IQI 3–7] vs. 2 [IQI 1–5]; P = 0.007). COPD patients had lower survival than no COPD patients (88.1% vs. 95.5%; P = 0.048) while no difference was found in terms of one-year …

Released: 11-Jan-2022 2:00 AM EST
Primary hemostatic disorders drive early and late major bleedings of patients with atrial fibrillation after transcatheter aortic valve replacement
Archives of Cardiovascular Diseases Supplements

… TAVR registry. Bleeding complications were assessed according to the VARC-2 criteria. Major adverse cardiac and cerebrovascular events (MACCE) was defined as a composite of all-cause death, myocardial infarction, stroke, and heart failure …

Released: 11-Jan-2022 2:00 AM EST
Prevention and management of peri procedural TAVR complications
Mini-invasive Surgery

… The majority of post-TAVR strokes occur within the first 24 h and are due to embolization of debris composed of thrombus, calcification, … this debris and thereby reduce the incidence of peri-procedural stroke. Currently, only two devices …


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