Feature Channels: Blood

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An article published on July 6, 2016 in The Lancet ranks viral hepatitis infections – specifically both Hepatitis B (HBV) and Hepatitis C (HCV) – as the seventh leading cause of death worldwide in 2013, up from tenth in 1990. …hepatitis C is a critical public health concern that, despite the consistent release of research stating its increasing adverse impact on public health, continues to see woeful underfunding for prevention and treatment initiatives to curtail its spread.

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For patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of North Carolina compared to a benchmark.

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Recent studies on a small number of patients with leukemia treated with bone marrow transplantation have suggested that the presence of the common cytomegalovirus (CMV) in patients or their donors may protect against relapse or even death after the transplant. A large international study published in the journal Blood now shows the opposite. The virus not only does not prevent leukemia relapse, but also remains a major factor associated with the risk of death.

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Vasculitis Foundation's "VF Team Brandon" supports Olympic hopeful's dream

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Multicenter, phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed/treatment-resistant lymphoma.

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Midwest Orthopaedics at Rush physicians find arthroscopic surgery to be effective, especially in those under 45.

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Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs.

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In a surprising twist, benign brain tumors that have previously been tied to obesity and diabetes are less likely to emerge in those with high blood sugar, new research has found.

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A study published in the New England Journal of Medicine on May 26 showed that participants who received a recombinant therapy— the present standard in the United States — developed antibodies or “inhibitors” to the treatments at almost twice the rate as those whose treatments were made from human plasma.

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Incorrectly folded proteins can cause a variety of diseases. Danish researchers have found a solution for preventing this misfolding.

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Blacks are four times more likely than their white counterparts to die from stroke at age 45.

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UCSF researchers that it is possible to generate healthy new liver cells in the livers of living mice by converting the very cells that drive liver disease, thereby reducing liver damage and improving liver function at the same time.

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Johns Hopkins scientists who indirectly investigated the blood sugar effects of 10 (out of 32 selected) commercial weight loss programs say a few show promise of benefit for diabetic patients, but far more rigorous research is needed before doctors can wholeheartedly recommend them.

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African study finds genes that double the chance of developing bacteraemia when infected with the Streptococcus pneumoniae bacteria.

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Dylan Martin wasn’t sure he’d ever be able to graduate from college, but his concern stemmed from something far more serious than how he was doing in his classes.

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Red blood cell exchange offers the risk lowering benefit of frequent blood transfusions but does so without increasing the iron stored in the body. Patients are connected to an apheresis machine which removes sickled red cells and replaces them with normal red cells from donors.

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In addition the technique to grow the blood vessels in a 3D scaffold cuts down on the risk of transplant rejection because it uses cells from the patient. It was developed by researchers from the University of Bath's Department of Pharmacy and Pharmacology, working with colleagues at Bristol Heart Institute.

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For the eighth year in a row, Loyola University Medical Center has received the American Heart Association/American Stroke Association’s Get With the Guidelines®-Stroke Gold Plus Quality Achievement Award.

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Mariana was brought to Loyola Medical Center to treat a rare brain tumor at the young age of five. Her treatment process was extensive, including surgery, radiation and intense chemotherapy. Throughout it all, Mariana kept an optimistic attitude.

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UT Southwestern Medical Center has joined an international consortium of leading universities to study the effectiveness of various stroke treatments from the patient’s perspective.

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Doctors change practice trends as debate continues on optimal time to administer antiplatelet therapy.

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A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threatening high blood pressure condition affecting 1 percent of all pregnant women.

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A study from Columbia University Medical Center found that lowering blood pressure goals for people with cardiovascular risk factors could save tens of thousands of lives annually and reduce costs.

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Diagnosing Mononucleosis, Need for Health Interventions for Single Parent Households in Urban Subsidized Housing Programs, Inadequate Financial Savings Tied to Increased Childhood Health Risks, and more in the Public Health News Source

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Synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases: beta-thalassemia and polycythemia vera. The compounds restored red blood cell levels of red blood cells and controlled iron absorption in animal models.

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University of Vermont blood-clotting expert Mary Cushman, M.D., M.Sc., talks about the reasons why sometimes fatal blood clots occur in elite athletes like the Portland Trail Blazers' Jerome Kersey, tennis great Serena Williams and most recently, the Miami Heat's Chris Bosh.

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Atrial fibrillation patients taking warfarin, a popular anticoagulation drug, are at higher risk of developing kidney failure if anticoagulation levels are not properly managed, according to a new study from researchers at the Intermountain Medical Center Heart Institute.

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Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18.

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Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source

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Discovery provides a serious advantage in determining how to maximize blood stem cells in therapeutics and could help ease current stem cell shortages.

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Cancer researchers at the University of Cincinnati (UC) have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.

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Early results suggest novel gene therapy is safe and effective for treatment of inherited immune disease, according to St. Jude Children’s Research Hospital and the National Institute of Allergy and Infectious Diseases.

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Colorectal cancers heavily bedecked with tumor-related proteins called neoantigens are likely to be permeated with disease-fighting white blood cells, researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard report in a new study.

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A new generation of blood thinners can reduce the risk of stroke in patients with atrial fibrillation, without requiring frequent monitoring and dietary restrictions.

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People with type 2 diabetes are at greater risk of serious liver disease than those without the condition, research has shown.

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Implementation of a multifaceted quality improvement intervention with daily checklists, goal setting, and clinician prompting did not reduce in-hospital mortality compared with routine care among critically ill patients treated in intensive care units (ICUs) in Brazil, according to a study appearing in the April 12 issue of JAMA.

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The American College of Radiology (ACR) — as a member of a coalition of leading medical societies — provided peripheral arterial disease (PAD) treatment recommendations to the Medicare Evidence Development Coverage Advisory Committee (MEDCAC). In addition, the coalition called for continued research in how to provide the best care for U.S. seniors with lower extremity PAD.

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Protective role for SHARPIN, a protein involved in regulating inflammation, according to report in The American Journal of Pathology.

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While controlling blood pressure, blood sugar and LDL-cholesterol levels reduces the risk of cardiovascular disease in people with diabetes, only 7 percent of diabetic participants in three major heart studies had recommended levels of these three factors, according to research from the Heart Disease Prevention Program at the University of California, Irvine School of Medicine.

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The investigational drug abaloparatide-SC (subcutaneous) may help increase bone mineral density in postmenopausal women and reduce their risk of fracture, new industry-sponsored research suggests. The results of the subgroup analysis within the ACTIVE clinical trial will be presented Friday, April 1, at ENDO 2016, the annual meeting of the Endocrine Society in Boston

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People with high levels of good cholesterol, or high-density lipoprotein, are not as safe from heart disease when high levels of a newly identified biomarker of inflammation in the arteries are also found in their bloodstream, according to a new study.

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Doctors have devised a test which could help them predict which women going through menopause will lose bone faster than average, new research reports. The results of the study will be presented Friday, April 1, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

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Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing celiac disease in people with celiac disease risk genes.

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Patients are often instructed not to take ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) before or after surgery because of increased bleeding risk. But available evidence suggests that ibuprofen does not increase the risk of bleeding after plastic surgery procedures, according to a research review in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).