Feature Channels: Transplantation

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Nisanne Ghonemi's research seeks to address a universal problem in kidney transplant surgery that can result in failure of the organ graft. Her research will explore the use of a class of drugs known as prostacyclins to reduce ischemia-reperfusion injury to a transplanted kidney from a deceased patient that can result in failure of the organ graft.

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The Department of Homeland Security has turned to ASU researchers for help developing advanced tools that will improve operations in DHS organizations, including the Transportation Security Administration, U.S. Coast Guard, Federal Emergency Management Agency and Customs and Border Patrol.

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Alina Franke registered to donate her bone marrow in Hamburg, Germany, in 2009. She wound up being the one person in 24 million around the world on the Be The Match registry to be the perfect match that Jimmy Roberson needed.

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Vanderbilt University Medical Center (VUMC) and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development.

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UCLA has received an $8.4 million grant from the National Institutes of Health to research ways to help donated livers last longer and improve outcomes for transplant recipients.

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Researchers in Germany have demonstrated that hematopoietic stem cell (HSC) transplants can be improved by treatments that temporarily prevent the stem cells from dying. The approach, which is described in a paper to be published September 7 in The Journal of Experimental Medicine, could allow those in need of such transplants, including leukemia and lymphoma patients, to be treated with fewer donor stem cells while limiting potential adverse side effects.

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A synthetic version of low molecular weight heparin is poised for clinical trials and development as a drug for patients with clotting disorders, and those undergoing procedures such as kidney dialysis, heart bypass surgery, stent implantation, and knee and hip replacement.

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Loyola Medicine's solid organ transplant program has reached another major milestone with the successful performance of its first pancreas transplant.

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Margaux Mustian and Laura Hickman say they pursued a career in transplant surgery in part due to the teaching and training they received from longtime UAB transplant surgeon Mark Deierhoi.

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Heat therapy may be a promising treatment against cancer and autoimmune diseases. University of Kentucky researchers exposed colorectal cancer cells and T-cells to temperatures high and low temperatures to observe the effects on cellular energy production.They will present their findings at the Physiological Bioenergetics: Mitochondria from Bench to Bedside conference in San Diego.

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Under the leadership of Rutgers University-New Brunswick scientist Dr. Joachim Kohn, a civilian research program established by the U.S. Department of Defense to focus on regenerative medicine for the treatment of battlefield injuries has made great strides that culminated in a total face transplant performed at the Cleveland Clinic in May.

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• There are very few high quality studies on strategies to increase living kidney donation. • From the limited data available, educational interventions directed at potential recipients and their social networks are the most promising.

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A new University of Michigan study finds slightly more than half of heart patients are admitted to the CICU for noncardiac conditions, such as sepsis or renal failure, rather than for a heart condition.

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The design of aeroplane wings and storing organs for transplant could both become safer and more effective, thanks to a synthetic antifreeze which prevents the growth of ice crystals, developed by researchers at the University of Warwick.

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The University of New Mexico Comprehensive Cancer Center began helping New Mexicans with blood disorders a little more than one year ago. It is the state’s only bone marrow transplant program. The program offers treatment choices for people with lymphoma and myeloma and will expand to help people with other blood disorders.

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