A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.
Gene variants associated with disease are typically considered faulty; problems arise when the proteins they make don't adequately carry out their designated role.
UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.
Biology isn't just for biologists anymore. That's nowhere more apparent than in the newly furnished lab in room 097 of the Shriram Center basement, where flasks of bacterial and animal cells, snug in their incubators, are churning out proteins destined for jobs they may not have done in nature.
Protecting the body against oxidative stress
Glenn Fleisig compiles biomechanical analysis from thousands of baseball players to find out what's behind the epidemic.
A biologist at The University of Texas at Dallas and his colleagues have discovered that two enzymes previously linked independently with keeping cancer cells alive actually work in tandem to spur tumor growth.
Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy.
Cancer is the second leading cause of death in the U.S., making early, reliable diagnosis and treatment a priority. Miniaturized lab-on-chip approaches are prime candidates for developing viable diagnostic tests and instruments because they are small, need only limited test volumes, and can be cost-effective. Researchers have developed just such an approach capable of processing biomolecular samples from blood. They describe their work in this week’s Biomicrofluidics.
Dr. Delbert E. Day, a prolific inventor whose work with specialty glasses has led to treatments for cancer, bone tissue regeneration and wound care, has been named a National Academy of Inventors Fellow.
It has been 20 years since Dolly the sheep was successfully cloned in Scotland, but cloning mammals remains a challenge. A new study by researchers from the U.S. and France of gene expression in developing clones now shows why most cloned embryos likely fail.
New research led by scientists at The Scripps Research Institute (TSRI) reveals that a human enzyme has changed little from its days as a bacterial enzyme.
A team of scientists has uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons.
Scientists examined one bacterium found 1,000 feet underground (called Paenibacillus) that demonstrated resistance to most antibiotics used today, including so-called ‘drugs of last resort’ such as daptomycin. These microorganisms have been isolated from the outside world for more than four million years within the cave.
Prominent research leader and biomedical scientist Professor Barry Halliwell will help to steer biomedical research efforts in Singapore at the Agency for Science, Technology and Research (A*STAR) from 1 January 2017.
A Queen’s University Belfast expert is leading a €4m international initiative to investigate whether natural toxins and manmade chemicals are creating potentially dangerous mixtures that affect our natural hormones and cause major illnesses such as cancer, obesity, diabetes or infertility.
The patent relates to the use of Streck’s proprietary Cell-Free DNA BCT CE product for the collection of samples to analyze fetal nucleic acid for non-invasive prenatal testing (NIPT).
A new commentary cautions that the Food and Drug Administration’s ban on triclosan and 18 other biocidal chemicals that promote antibiotic resistance is only a starting point. Triclosan’s long-term impact, as well the risks substitute chemicals may pose, must also be addressed.
FAU's Schmidt College of Medicine recently appointed Janet Robishaw, Ph.D., as chair of the Department of Biomedical Sciences. Robishaw, an accomplished functional and translational genomics researcher with 30 years of sustained federal funding from the NIH, comes to FAU from Geisinger Health System in central Pennsylvania.
Demonstration that bacteria can drive mating in eukaryotes raises possibility that environmental bacteria or bacterial symbionts may influence mating in animals
More than 46,000 species of spiders creepy crawl across the globe. Each one produces a venom composed of an average of 500 distinct toxins, putting the conservative estimate of unique venom compounds at more than 22 million. Researchers are studying these toxins to increase our understanding of the evolution of spider venom and contribute to the development of new medicines, anti-venoms and research tools.
Marathon event highlights coding and biotech skills to develop solutions related to food, agriculture and healthcare technology
As part of an effort to develop drought-resistant food and bioenergy crops, scientists at the Department of Energy’s Oak Ridge National Laboratory have uncovered the genetic and metabolic mechanisms that allow certain plants to conserve water and thrive in semi-arid climates.
Stephen Elledge, the Gregor Mendel Professor of Genetics and of Medicine at Brigham and Women’s Hospital and Harvard Medical School, has been named a 2017 recipient of the Breakthrough Prize, which recognizes paradigm-shifting discoveries in the life sciences, physics and mathematics. Elledge is being honored for his wide-ranging contributions across multiple fields in biology.
Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person’s blood 95 times faster than current methods—using only a single drop of blood.
ASCB names 10 "Novel & Newsworthy" Honor abstracts out of 1263 being presented in San Francisco, Dec. 3-7
Analysis of a phase 3 trial shows that older patients with high-risk or secondary AML, who received initial treatment with CPX-351, had improved survival following allogeneic hematopoietic cell transplant, when compared with patients who received standard 7+3 cytarabine and daunorubicin as initial therapy.
Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light.
Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style. That’s according to scientists at Cornell’s Baker Institute for Animal Health, the first team to recreate a 10-step biological pathway with all the enzymes tethered to nanoparticles.
Matthew Webber, University of Notre Dame professor, tested a novel route for non-covalent protein modification and results reveal a new way to improve the stability of common protein drugs and extend shelf-life.
Networks evolve in different ways depending how often "second neighbor," or friends of friends, connections occur.
In colder weather, people have long been warming up around campfires and woodstoves. Lately, this idea of burning wood or other biomass for heat has surged in popularity as an alternative to using fossil fuels. Now, in the journal ACS Sustainable Chemistry & Engineering, scientists report a step toward a "greener" way to generate heat with biomass. Rather than burning it, which releases pollutants, they let fungi break it down to release heat.
UBC researchers develop new method to test for antioxidants in chocolate
The portfolio of patents focuses on the PKG (protein kinase G) pathway, which plays a pivotal role in several neurological conditions by controlling cortical spreading depolarization. Research at FAU has found that neurological diseases, including hemiplegic migraine – a severe type of migraine that can affect patients up to 15 times a month and can paralyze half the body – as well as neural trauma (traumatic brain injury and spinal shock), stroke, and epileptic conditions can be targeted through the PKG signaling pathway.
Researchers from North Carolina State University have discovered a way to make pinpoint changes to an enzyme-driven “assembly line” that will enable scientists to improve or change the properties of existing antibiotics as well as create designer compounds.
Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol. The software could be used to help reduce the risk of liver failure and overdose death in this and other drugs.
A new bioinformatics platform called Empowering the Development of Genomics Expertise (EDGE) will help democratize the genomics revolution by allowing users with limited bioinformatics expertise to quickly analyze and interpret genomic sequence data.
A new University of Washington study of one of our closest invertebrate relatives, the acorn worm, reveals that regenerating body parts might one day be possible.
UW-Madison Professor James Steele’s new company, Lactic Solutions, is using genetic engineering to, instead of killing lactic acid bacteria with antibiotics, splicing in genes for ethanol production so these organisms produce ethanol, not lactic acid.
A combination of experiments, including X-ray studies at Berkeley Lab, revealed new details about pesky deposits that can stop chemical reactions vital to fuel production and other processes.
A team of biomedical engineering researchers at the University of Arkansas have identified a cause of fluid swelling of the brain, or cellular edema, that occurs during a concussion.
Mark R. Chance, PhD, vice dean for research at Case Western Reserve University School of Medicine, has been named a fellow of the American Association for the Advancement of Science.
Bioplastic may offer gardeners a more sustainable alternative to petroleum-based pots and flats, according to Iowa State University research. Although more expensive to manufacture than conventional plastics, bioplastics someday may grow beyond a niche market, said ISU experts.
Five scientists from Lawrence Berkeley National Laboratory have been named Fellows of the American Association for the Advancement of Science (AAAS). Election as a AAAS Fellow is an honor bestowed upon AAAS members by their peers.
Cells synthesize millions of proteins every minute. Three pioneering protein quality control researchers will explain at ASCB 2016 how studying protein folding and misfolding is opening unexpected pathways for treating cancer and neurodegenerative diseases
Two scientists at The Scripps Research Institute (TSRI) have been elected fellows of the American Association for the Advancement of Science (AAAS).
Ten Rutgers have been named fellows of the American Association for the Advancement of Science (AAAS), an honor conferred on 381 other experts in the U.S. and abroad. The fellows were chosen by their AAAS peers for efforts to advance science applications that are deemed scientifically or socially distinguished, according to the AAAS.
New X-ray methods at the Department of Energy’s SLAC National Accelerator Laboratory have captured the highest resolution room-temperature images of protein complex photosystem II, which allows scientists to closely watch how water is split during photosynthesis at the temperature at which it occurs naturally.
Researchers at Argonne National Laboratory have conducted a detailed study of the albedo (reflectivity) effects of converting land to grow biofuel crops. Based on changes in albedo alone, their findings reveal that greenhouse gas emissions in land use change scenarios represent a net warming effect for ethanol made from miscanthus grass and switchgrass, but a net cooling effect for ethanol made from corn.
The popularity of forensics and crime scene investigation fueled by a glut of television programs has familiarized many of us with the basics of forensic medicine. However, not much is, in fact, understood about blood back spatter. A team of researchers from the University of Illinois and Iowa State University is exploring the science behind blood back spatter using fluid dynamics to develop a theoretical model for predicting and interpreting blood spatter from gunshot wounds, and it could significantly impact the field of forensic science. The work will be presented at the 69th Annual Meeting of the APS Division of Fluid Dynamics held in Portland, Oregon, Nov. 20-22, 2016.
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