Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to data from an analysis of the Women’s Health Initiative observational study.
Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The U.S. Congress will soon be facing another budget showdown as their sixth continuing resolution expires on April 8, 2011. While the entire government has been without permanent appropriations for nearly six months, the House Republicans and Senate Democrats continue to remain far apart on resolving the fiscal year (FY) 2011 budget.
In the largest study of its kind, researchers from a consortium of 44 universities and research institutions in the United States, including Rush University Medical Center, identified four new genes linked to Alzheimer’s disease. Each gene individually adds to the risk of having this common form of dementia later in life.
Promising new research reveals a potentially highly effective treatment for heterotopic ossification (HO), a painful abnormal buildup of bone tissue. HO has two main forms—one in children, another in wounded soldiers.
Researchers from a consortium that includes Columbia University Medical Center identified four new genes linked to late-onset Alzheimer’s disease, each of which adds to the risk of developing this most common form of the disease. Together they offer a portal into the causes of Alzheimer’s. Their identification will help researchers find ways to determine who is at risk of developing the disease and to identify proteins and pathways for drug development.
Researchers at Columbia University Medical Center have developed a new way to stimulate neuron production in the adult mouse brain, demonstrating that neurons acquired in the brain's hippocampus during adulthood improve certain cognitive functions.
Cancer Discovery, the newest journal in the robust publication program of the American Association for Cancer Research, will debut at the AACR 102nd Annual Meeting 2011, held here from April 2-6.
Scientists have uncovered a genetic characteristic of metastatic prostate cancer that defines a rare sub-type of this disease. These findings are published in Cancer Discovery, the newest journal of the American Association for Cancer Research, which will debut at the AACR 102nd Annual Meeting 2011, held April 2-6.
Scientists at the Dana Farber Cancer Institute have identified a mutation in the DDR2 gene that may indicate which patients with squamous cell lung cancer will respond to dasatinib.
A study published in Cancer Discovery, the newest journal of the American Association for Cancer Research, debuting here at the AACR 102nd Annual Meeting 2011, held April 2-6, showed how evaluating the immune response in the tumor microenvironment may help researchers better target therapy in breast cancer.
Scientists have identified digoxin as a possible therapy for prostate cancer, using a combination of laboratory science and epidemiology that is unprecedented in its cooperative nature.
Johns Hopkins scientists and their colleagues paired laboratory and epidemiologic data to find that men using the cardiac drug, digoxin, had a 24 percent lower risk for prostate cancer. The scientists say further research about the discovery may lead to use of the drug, or new ones that work the same way, to treat the cancer.
Using new genetic information, scientists have linked a commonly found human genetic variant with both longer telomeres and reduced risk of bladder cancer, according to findings presented at the AACR 102nd Annual Meeting 2011, held April 2-6, and simultaneously published in Cancer Prevention Research, a journal of the American Association for Cancer Research.
Results of a study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, lend credence to the idea that improving quality of life affects stress-related biological markers and possibly the health of people with cancer.
Evidence continues to build that telomeres, cell endings that fray as we age, are affected by stress and are predictive of cancer risk. Scientists will present new groundbreaking research in this area of study at an AACR 102nd Annual Meeting 2011 press conference held on Sunday, April 2 at 2:00 p.m. ET in room W313 of the Orange County Convention Center.
A common genetic variation links to both bladder cancer risk and to the length of protective caps found on the ends of chromosomes, scientists at The University of Texas MD Anderson Cancer Center reported today at the AACR 102nd Annual Meeting.
The American Association for Cancer Research Annual Meeting continues to be a showcase for the most cutting edge science in cancer, and this year’s meeting, held here April 2-6, will include an increased focus on clinical trials that will impact patient care.
A new hedgehog pathway inhibitor demonstrated efficacy in preventing and treating basal cell cancer among patients with basal cell nevus syndrome, a rare inheritable disease, according to Phase II data presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Scientists are continuing their work on the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination trial — known more commonly as the BATTLE trial — and presented updated results at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The combination of two compounds that inhibit two of the most frequently mutated cancer pathways is showing promise in an ongoing Phase I trial, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Scientists have identified a biomarker for measuring the success of lung cancer chemoprevention, an emerging frontier in the fight against this disease that has long been stymied by a lack of measureable outcomes. These study results were presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
In one of the largest cancer genomics investigations reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. This comparison allowed researchers to find mutations that only occurred in the cancer cells.
In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine.
Analysis published this week in the journal Science shows how declines of bat populations caused by a new wildlife disease and fatalities at industrial-scale wind turbines could lead to substantial economic losses on the farm.
A landmark breast health care publication reveals a multitude of barriers that keep women of developing nations from being screened and treated for breast cancer – but offers tools to help countries improve their breast care programs.
1) Test conducted in the non-cancerous part of the prostate; 2) May aid in localization of cancer lesion within the prostate gland.
In a finding that could help fight terrorism and improve safety in laboratories working with explosive chemicals, scientists are reporting development of a new material made of nanoparticles that can quickly detect and neutralize explosives. Soldiers, firefighters, lab workers could spray the material onto bombs or suspected explosives to make them no longer harmful, the scientists said. They will describe the new material at the 241st National Meeting of the American Chemical Society in Anaheim.
Dana-Farber Cancer Institute president: Trends are encouraging, but more improvements are needed.
In a scientific advance literally plucked from the waste heap, scientists today described a key step toward using the billions of pounds of waste chicken feathers produced each year to make one of the most important kinds of plastic. They described the new method at the 241st National Meeting and Exposition of the American Chemical Society, being held here this week.
A study of newly installed, hands-free faucets at The Johns Hopkins Hospital, all equipped with the latest electronic-eye sensors to automatically detect hands and dispense preset amounts of water, shows they were more likely to be contaminated with one of the most common and hazardous bacteria in hospitals compared to old-style fixtures with separate handles for hot and cold water.
Soldiers and contractors stationed in Iraq not only face enemy gunfire and the threat of roadside bombs, but every day they breathe air polluted with dust particles carrying lead and other contaminants as much as 10 times above desirable level cited in U.S. National Ambient Air Quality Standards.
In the first report on the uptake and internal processing of triclocarban (TCC) in fish, scientists today reported strong evidence that TCC — the source of environmental health concerns because of its potential endocrine-disrupting effects — has a “strong” tendency to bioaccumulate in fish. They presented the findings here today at the 241st National Meeting of the American Chemical Society.
The next-generation battery, like next-generation TV, may be 3-D, scientists reported at the 241st National Meeting and Exposition of the American Chemical Society (ACS) in Anaheim, CA. They described a new fast-recharge lithium-ion (Li-on) battery, already available in a prototype version, with a three-dimensional interior architecture that could be perfect for the electric cars now appearing in auto dealer showrooms
The lead article in the April 4 issue of the journal Academic Medicine connects research on how the brain learns to how to incorporate this understanding into real world education, particularly the education of medical doctors.
A three-drug cocktail can eliminate the hepatitis C virus in patients far more effectively than the current two-drug regimen, according to researchers at Henry Ford Hospital. The results of the global study are in the March 31 issue of The New England Journal of Medicine.
Giving girls with Turner syndrome low doses of estrogen, as well as growth hormone, years before the onset of puberty, increases their height and offers a wealth of other benefits, say a team of researchers led by Thomas Jefferson University. Their report is published in the March 31st issue of The New England Journal of Medicine (NEJM).
For obese seniors, dieting and exercise together are more effective at improving physical performance and reducing frailty than either alone. Although weight loss alone and exercise alone improve physical function, neither is as effective as diet and exercise together, which improved physical performance in seniors by 21 percent.
Saint Louis University investigator Bruce Bacon, M.D., reports findings in the New England Journal of Medicine.
Basic Yellow 1, a dye used in neuroscience labs around the world, is a wonder drug for nematode worms. Thioflavin T extended lifespan in healthy worms by more than 50 percent and slowed the disease process in worms bred to mimic aspects of Alzheimer’s. The research could open new ways to intervene in aging and age-related disease.
The most recently discovered amino acid, pyrrolysine, is produced by a series of just three chemical reactions with a single precursor – the amino acid lysine, according to new research.
The American College of Rheumatology has developed new guidelines for starting and monitoring treatments for children with juvenile idiopathic arthritis. These are the first JIA guidelines endorsed by the ACR, with the goal of broad acceptance within the rheumatology community.
The Clorox Company announced today that the U.S. Environmental Protection Agency (EPA) approved the registration of DISPATCH® Hospital Cleaner Disinfectant Towels with Bleach to kill Clostridium difficile (C. difficile) spores in five minutes, the fastest C. difficile contact time available. This is the first bleach-based wipe to receive EPA registration for C. difficile, a spore-forming bacterium found in the intestines that can cause a variety of symptoms, from diarrhea to more serious life-threatening intestinal disease.
Scientists have identified ingredients in an herb used in traditional Chinese medicine that show promise as a safer, more effective alternative to current skin-whitening cosmetics, which can cause problems ranging from allergic reactions to skin cancer. The finding could be a boon to women in Asian countries, where skin-whitening is a common beauty practice. Scientists will describe the new method and materials at the 241st National Meeting of the American Chemical Society in Anaheim.
In the event of a much-feared bioterror attack involving ricin, food manufacturers may want to reach for the laundry cabinet. That’s because household bleach appears to be an effective, low-cost way to decontaminate the toxin on metal food preparation surfaces, scientists are reporting. They will describe the finding in Anaheim, Calif., during the 241st National Meeting and Exposition of the American Chemical Society (ACS).
UAB researchers have found the mechanism used by malignant glioma cells to travel and spread through the brain, and may have come upon a method to interfere with that spread.
Neglected infections of poverty are the latest threat plaguing the poorest people living in the Gulf Coast states and in Washington, D.C., according to Dr. Peter Hotez, Distinguished Research Professor and Chair of the Department of Microbiology, Immunology, and Tropical Medicine at The George Washington University and President of the Sabin Vaccine Institute, in an editorial published in the open-access journal PLoS Neglected Tropical Diseases on March 29th.
Wrapping antibiotics in nanofibers so tiny they can’t be seen under a microscope, and injecting them into the body, turns bacteria and fungi that cause food poisoning and hospital-acquired infections into ghosts of themselves, potentially overcoming the growing problem of antimicrobial resistance.
Coating concrete destined to rebuild America’s crumbling bridges and roadways with millions of tons of underused flyash waste from burning coal could extend the life of the structures significantly, saving billions of dollars, scientists reported here.
A study by Joslin Diabetes Center researchers has found that some people who have survived diabetes for many decades show remarkably few complications—a discovery that points toward the presence of protective factors that guard against the disease's effects.
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