… cells remains eliciting the desired stem cell behavior once transplanted in the body. In their natural environment, stem cell fate is regulated by their … ECM ligands, as well as soluble cues, making MSN-ssDNA based biointerfaces a novel tool to …
… Importantly, we demonstrate that Aux interacts with EGFR and safeguards the activation of EGFR to maintain a proper stem cell proliferation rate. Thus, our data uncover the underlying mechanism of Aux in stem cell proliferation control and …
… This article briefly introduced the regulatory framework development, the progress in stem cell clinical researches and clinical trials of commercially developed stem cell-based products, as well as the clinical review concerns of stem cell-based products in …
In this review, we will outline dimensions in which outcome of patients with myelofibrosis undergoing curative treatment can be optimized: patient selection, transplant procedure, and posttransplant prevention or treatment of relapse. For …
… of etoposide and cytarabine [8], or intensive chemotherapy followed by autologous stem cell transplantation (IC-ASCT) [9, 10]. Thiotepa-based myeloablative chemotherapy followed by autologous stem cell transplantation (ASCT) …
… Owing to the fact that MSC-derived exosomes can further control stem cell differentiation by carrying and transferring miRNAs, stem cell-based exosome therapeutic regimens have been highlighted as effective means for cardiac …
The widespread clinical application of cord blood (CB) for hematopoietic stem cell (HSC) transplantation is limited mainly by the inadequate number of hematopoietic stem and progenitor cells (HSPCs) in single CB units, which results in unsuccessful or …
… Mesenchymal stem cell-derived EV have been shown to contain a diverse array of bioactive cargo, including proteins, nucleic acids, non-coding RNA and lipids. The lipid bilayer of the EV membrane protects the cargo from degradation and is often …
Mohamadamin Forouzandehmehr, Michelangelo Paci, Jussi Koivumäki, Jari Hyttinen
In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscle-wasting disorders in people.
Yeqing Yang, Junkai Zeng, Chong Jiang, Jiawen Chen, Ming Chen, Buling Wu
Hanan Al-Abboh, Akmal Zahra, Adekunle Adekile
Fei Jiao, Xiao Zhang, Chongyang Ye, Qing Sun, Yan Gao, Chenglin Liu, Bo Huo
Zhen Yu, Shuai Tong, Can Zhang, Yue Bai, Zhijing An, Chang Xu, Fang Wang, Yi Hu, Qinghui Zhuang, Xiaosong Zhong
Rodrigo García-Tejera, Linus Schumacher, Ramon Grima
In this issue of Cell Stem Cell, Reilly et al. propose loss of LMNB1, the gene encoding lamin B1, often deleted in MDS/AML, as a novel genetic basis for the abnormal nuclear shape of neutrophils (known as acquired Pelger-Huët anomaly) and a cause o
(Cell Stem Cell 29, 515–527.e1–e8; April 7, 2022)
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right