New Advancements in Assay Development Research
SLASThe July 2023 issue of SLAS Discovery, the open access journal focused on research progressing drug discovery, is now available.
The July 2023 issue of SLAS Discovery, the open access journal focused on research progressing drug discovery, is now available.
Rather than turn to vices such as alcohol and drugs, many people turned to new pursuits to cope with pandemic-related stresses, according to a Rutgers study.
Women with Lyme disease take longer to get diagnosed, have more severe symptoms and experience higher rates of disability when compared to men.
Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.
People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve. They’re more than twice as likely as those who become symptomatic to carry a specific gene variation that helps them obliterate the virus, according to a new study led by UC San Francisco researchers.
Scent dogs may represent a cheaper, faster and more effective way to detect COVID-19, and could be a key tool in future pandemics, a new review of recent research suggests.
The fight against dengue fever has a new weapon: a mosquito infected with the bacteria Wolbachia, which prevents the spread of the virus. These mosquitoes have now been deployed in several trials demonstrating their potential in preventing disease transmission.
BU research highlights how healthcare inequities between urban and rural areas, and vaccine skepticism, played a role in deaths related to COVID.
The COVID-19 pandemic hit the educational systems. It is estimated that approximately 1.6 billion children worldwide were affected by school closures, which had a major impact on their learning.
Researchers have cracked how a particular type of immune cell develops in the body and protects against infection and disease. And the discovery could help in the development of more preventive treatments, according to a new study.
Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA. The resulting nanostructures could have applications in vaccine development and transporting drugs inside the body.
Improving diagnosis in health care is a moral, professional and public health imperative, according to the U.S. National Academy of Medicine.
A new study conducted by Luther College finds that a neuroplasticity-based treatment using an online amygdala & insula retraining (AIR) program significantly reduces fatigue and increases energy levels among Long COVID patients when compared to a general wellness program.
Human papillomavirus (HPV) is a ubiquitous virus, and most people are infected at some point in their lives. HPV can infect epithelial cells of the skin and mucosa at various sites.
High rates of smoking among people with HIV are associated with high rates of comorbid health problems – which are associated with characteristics including gender, race/ethnicity, and socioeconomic status, according to a study in the July issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.
As the UK Covid inquiry continues for a fifth week, researchers at the University of East Anglia have created a unique snapshot of lockdown life.
In a first-of-its-kind study that controlled for individuals’ biological factors, researchers found that people who lived in multi-family housing, or in areas with higher levels of air pollution and access to public transit, were at a higher risk of hospitalization from COVID-19 in the Denver Metro Area in 2020.
The number of young people in the United States visiting hospital emergency departments for mental health crises increased sharply during the second year of the COVID-19 pandemic, according to a study led by researchers from the Department of Health Care Policy in the Blavatnik Institute at Harvard Medical School.
Five medical societies have published a set of recommendations for operationalizing strategies for infection prevention in acute care settings that account for conditions within the facility, including the culture and communications style of teams, hospital policies, resources available, leadership support and staff buy-in.
People seeking mental health services during the COVID-19 pandemic were not deterred by the widespread shift to telehealth services, according to research findings published in the Journal of Counseling & Development, a journal of the American Counseling Association.
Modern mosquito bed nets also come with insecticidal compounds embedded into the fibers that keep mosquito populations down. In recent years, however, insecticide-resistant mosquitoes have curtailed the nets' effectiveness.
Two drugs commonly used to treat inflammatory diseases such as rheumatoid arthritis and psoriasis did not shorten recovery time for patients hospitalized with severe COVID-19 but did reduce the likelihood of death when compared with standard care alone, according to a national study led by Washington University School of Medicine in St. Louis.
With new cases of malaria being reported in Texas and Florida, researchers at UT Southwestern Medical Center continue to explore compounds for more effective drug-resistant therapies and biological targets to interfere with the parasites that spread the potentially fatal disease.
Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of the SARS-CoV-2 virus variants in a room in about 5 minutes.
Investigating viruses with spillover potential could give us a head start on the next pandemic and minimize its severity; one such virus is RshTT200, discovered in Cambodian bats in 2010. During ACA’s 73rd annual meeting, July 7-11, Samantha Zepeda from the University of Washington will present her team’s investigation into RshTT200. The team used cryo-electron microscopy to solve the spike protein structure. Once the spike proteins were understood, they built harmless, nonreplicating pseudoviruses expressing the spike proteins to investigate how RshTT200 accesses human cells.
Scientists at McMaster University and India’s University of Delhi have discovered and isolated the first live culture of the drug-resistant pathogen Candida auris from an animal, specifically from the ear canals of stray dogs.
Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines have identified an enzyme that plays a critical role in the late stages of HIV replication.
Wastewater monitoring could act as an early warning system to help countries better prepare for future pandemics, according to a new study.
A new study conducted by researchers at Bar-Ilan University in Israel has shed light on the long-term impact of COVID-19 on the quality of life among different ethnic groups in the country. The study, part of a larger cohort project, highlights a significant discrepancy between Arabs and Druze, and Jews, with the two former groups experiencing a more pronounced decline in quality of life one year after infection.
Kenyan patients who spend more than three days in the nation’s hospitals are more likely to harbor a form of bacteria resistant to one of the most widely used antibiotic classes, according to a recent study led by Washington State University.
Global efforts to reduce infectious disease rates must have a greater focus on older children and adolescents after a shift in disease burden onto this demographic, according to a new study.
A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.
Long Covid, which affects nearly two-million people in the UK (1), is not caused by an immune inflammatory reaction to COVID-19, University of Bristol-led research finds. Emerging data demonstrates that immune activation may persist for months after COVID-19.
A team of scientists from Okayama University, Japan demonstrated the relationship between vaginal microbiota and RC by comparing the vaginal microbiota of postmenopausal women with and without cystitis.
A UCLA-led team has received $925,000 as part of a new grant from the Centers for Disease Control and Prevention (CDC) to conduct four surveillance projects tracking outbreaks of mpox--formerly known as monkeypox—across the U.S.
Exploding populations of wild pigs and macaque monkeys in Southeast Asia are threatening native forests and disease outbreaks in livestock and people, according to research led by The University of Queensland.
In 2019, incarcerated people across the globe developed tuberculosis (TB) at nearly 10 times the rate of people in the general population, according to a new study led by Boston University School of Public Health (BUSPH).
COVID-19 vaccination helped reduce disparities in disease incidence between low- and high-income communities, according to a new analysis led by Cedars-Sinai investigators.
Ticks can be attracted across air gaps several times larger than themselves by the static electricity that their hosts naturally accumulate, researchers at the University of Bristol have discovered.