Substitute, for-hire physicians commonly care for hospitalized patients when doctors are sick or away. Information about outcomes is largely lacking, but a new study brings some much-needed insight. Results show no differences in 30-day mortality rates among patients treated by temporary physicians.
A team led by Tufts University biologists has successfully harnessed new technology to develop an approach that could allow for rapid and precise identification of the CGRs involved in disease, cancer and disorder development, which is critical for diagnosis and treatment. The results appeared this week in the December issue of Genome Research.
Babson College is offering four-year, full-tuition Diversity Leadership Awards to public high school students in San Francisco, Miami, and Boston, as well as neighboring Lawrence, Massachusetts. Students receiving such scholarships demonstrate the greatest potential for leadership in creating a diverse community at Babson. In addition to its main campus located in Wellesley, Massachusetts, Babson has established education hubs in Boston, San Francisco, and Miami, which is why students from these communities are being offered this opportunity.
Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika virus vaccine, according to interim analyses of three Phase 1, placebo-controlled, double-blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of Research (WRAIR), and Saint Louis University School of Medicine. The findings were published today in The Lancet.
Led by researchers in the Smith Center for Outcomes Research in Cardiology at Beth Israel Deaconess Medical Center (BIDMC), the large-scale analysis determined that 30 percent of readmissions following peripheral revascularization were related to complications associated with the procedure, while differences in hospital quality accounted only modestly for readmission risk.
New study finds that death rates for those hospitalized for opioid-related conditions in the U.S. have quadrupled since 2000. Worst toll seen among patients who were low-income, white, under age 65 and on Medicare, and the severity of opioid misuse leading to hospitalization has increased.
The Universal Genomics Instructor Handbook and Toolkit, a new, free educational resource designed to educate clinicians in all medical specialties in genomic medicine, is now available to improve physician genomic education worldwide. Developed by a team led by Richard L. Haspel, MD, PhD, Pathologist at Beth Israel Deaconess Medical Center (BIDMC) and Associate Professor of Pathology at Harvard Medical School, the handbook and accompanying online toolkit were developed through funding from The National Human Genome Research Institute (NHGRI), one of the 27 institutes and centers at the National Institute of Health.
Researchers at Tufts are examining the behavior of stem cells within the context of aging and loss of smell. In Cell Stem Cell, they report mechanisms to regenerate adult stem cells in mice to restore smell cells: it mimics induced pluripotency, but is simpler, involving only two Yamanaka factors.
Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth. In a study published today in the Journal of Experimental Medicine, the team has illuminated the mechanism by which tumor cell death can drive primary tumor growth and metastasis.
Head and neck tumors that contain cells undergoing a partial epithelial-to-mesenchymal transition — which transforms them from neatly organized blocks into irregular structures that extrude into the surrounding environment — are more likely to invade and spread to other parts of the body, according to a new study led by researchers from Mass. Eye and Ear, Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard.
BOSTON – (November 29, 2017) – Scientists at Joslin Diabetes Center have taken another step toward solving a long-standing puzzle about heart health in type 2 diabetes, with a finding that eventually may point towards more personalized patient care.People with type 2 diabetes, who are at least twice as likely to develop cardiovascular disease (CVD) as people without the condition, generally can reduce their risks by careful controlling their glycemic (blood glucose) levels.
Xiaocheng Jiang, assistant professor of biomedical engineering in the School of Engineering at Tufts University, has been awarded an early-career award from the Air Force Office of Scientific Research (AFOSR) for his work developing graphene-based microfluidics for ultra-high-resolution, dynamic bio-imaging.
Allan Cohen, Babson College management professor, and David L. Bradford, Senior Lecturer on Organizational Behavior Emeritus at Stanford Graduate School of Business, have released the third edition of ‘Influence Without Authority.’
Some individuals’ skin appears more youthful than their chronologic age. Although many people try to achieve this with creams, lotions, injections, and surgeries, new research published in the Journal of the American Academy of Dermatology indicates that increased expression of certain genes may be the key to intrinsically younger looking — and younger behaving — skin.
The first large Medicare pay-for-performance program for doctors and medical practices, which ran between 2013 and 2016, failed to deliver on its central promise to increase value of care for patients. The program may have also exacerbated health disparities by inadvertently shifting payments from physicians caring for sicker, poorer patients to those caring for healthier, richer ones. Important similarities between the failed pay-for-performance prototype and its successor suggest the latter may not be sound policy.
Changing the prices of seven foods, including fruits, vegetables and sugar-sweetened beverages, could reduce annual deaths from stroke, diabetes and cardiovascular disease by 3-9 percent and address disparities in the United States.
OpenNotes has reached a new milestone. More than 20 million patients can now read their notes securely online using patient portals.
Babson College has been selected as a Davis School by the Davis United World College Scholars Program. International students that have completed their final years of high school at one of the 17 United World Colleges will be eligible for need-based scholarships to attend Babson as undergraduate students.
Pier Paolo Pandolfi, MD, PhD, Director of the Cancer Center and Cancer Research Institute at Beth Israel Deaconess Medical Center (BIDMC), has been named a Fellow of the American Association for the Advancement of Science (AAAS).
Babson College Entrepreneurship Division Chair Andrew Corbett has been named the Paul T. Babson Professor of Entrepreneurial Studies.
Poor nutrition and lack of exercise lead to the increasing prevalence of obesity which, in turn, is the major predictor of diabetes and future risk of cardiovascular disease in western societies. Excess weight is also closely associated with obstructive sleep apnea (OSA), the increasingly common and potentially serious sleep disorder that is often marked by loud snoring. OSA affects about 5 to 10 percent of children 8 to 11 years old. While evidence suggests that OSA appears to exacerbate obesity and its comorbidities such as diabetes and cardiovascular disease, its effects on children have not yet been studied in detail.
Most Americans strongly support a U.S. foreign policy that promotes global gender equality, according to a new survey by researchers at Tufts University. The survey also found that Americans’ support for the advancement of women and girls remains high even when those goals conflict with priorities, such as international trade or relations with friends and allies.
Depletion of a fatty molecule in human blood propels malaria parasites to stop replicating and causing illness in people and instead to jump ship to mosquitoes to continue the transmission cycle, according to a new study by an international research team.
Babson College will host its first-ever international Rocket Pitch competition at Municipalidad de Vitacura in Santiago, Chile, on Thursday, November 23, 2017.
A common and potentially serious sleep disorder, obstructive sleep apnea affects at least one quarter of U.S. adults and is linked to increased risk of diabetes, obesity and cardiovascular disease. In a paper published today in the journal Neuron, researchers at Beth Israel Deaconess Medical Center (BIDMC) identified specific neural circuitry responsible for rousing the brain of mice in simulated apnea conditions. The findings could lead to potential new drug therapies to help patients with obstructive sleep apnea get more rest.
Drug exposure can cause significant changes in gene expression without affecting growth or survival in some cell lines, highlighting strategies to better evaluate drug effectiveness.
Babson College and its Lewis Institute for Social Innovation have launched a new IoT For Good Lab—to encourage the creation of social impact solutions with the use of IoT (Internet of Things).
Following a successful clinical trial involving Dana-Farber Cancer Institute and Brigham and Women’s Hospital, the first chimeric antigen receptor (CAR) T-cell therapy for adult cancers was approved by the Food and Drug Administration (FDA) today. Dana-Farber/Brigham and Women’s Cancer Center, the only facility in the northeast to be part of the clinical trial, is one of a few locations certified to offer this new therapy nationwide.
A team of scientists has uncovered a surprising molecular link connecting how cells regulate growth with how they sense and make available nutrients. The findings also implicate a new protein as a potential drug target in pancreatic cancer.
For many people with hearing challenges, trying to follow a conversation in a crowded restaurant or other noisy venue is a major struggle, even with hearing aids. Now, Mass. Eye and Ear researchers reporting in Current Biology on October 19th have some good news: time spent playing a specially designed, brain-training audiogame could help.
Breast cancer cells recycle ammonia, a waste byproduct of cell metabolism, and use it as a source of nitrogen to fuel tumor growth. The insights shed light on the biological role of ammonia in cancer and may inform the design of new therapeutic strategies to slow tumor growth.
Babson College, ranked No. 1 for entrepreneurship, has announced the appointment of William B. Gartner as its first Bertarelli Foundation Distinguished Professor of Family Entrepreneurship—generously endowed by the Bertarelli Foundation through a substantial gift to the college.
In discovering how certain chemotherapy drugs cause the nerve damage known as peripheral neuropathy, researchers at Dana-Farber Cancer Institute have found a potential approach to preventing this common and troublesome side effect of cancer treatment.
Research led by scientists at Beth Israel Deaconess Medical Center (BIDMC) demonstrated that epidural medication had no effect on the duration of the second stage of labor, normal vaginal delivery rate, incidence of episiotomy, the position of the fetus at birth or any other measure of fetal well-being the researchers investigated. The study compared the effects of catheter-infused, low-concentration epidural anesthetic to a catheter-infused saline placebo in this double-blinded, randomized trial of 400 women.
For the first time, scientists have directly linked deletions in two genes in zebrafish and traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes are in a genome region linked to autism spectrum disorder, developmental delays, seizures, and obesity in humans
Many prostate cancers, which generally are diagnosed in older men, are "indolent," slow-growing tumors that aren't destined to be fatal. But some tumors are prone to becoming aggressive and spreading beyond the prostate, making them difficult to treat and life-threatening. Currently, doctors have limited ability to predict which newly diagnosed tumors will progress slowly and which will probably undergo dangerous spread.
Four Harvard Medical School scientists are among 86 recipients nationwide honored by the National Institutes of Health High-Risk, High-Reward Research Program.
Assistant Professor of Design Sara Hendren has been named a 2018 Eric and Wendy Schmidt Fellow at New America.
BOSTON – (October 3, 2017) – If you’re one of the two billion people in the world who are over-weight or obese, or the one billion people with fatty liver disease, your doctor’s first advice is to cut calories—and especially to cut down on concentrated sugars such as high-fructose corn syrup, a sugar found in sweetened beverages and many other processed foods.
Proactive monitoring of blood levels of the therapeutic drug infliximab was associated with improved outcomes including lower risk of surgery and hospitalization.
Joslin’s research involves a wide variety of biologic disciplines ranging from the most basic model systems to studies of pathophysiology in animal models and humans to the evaluation of new therapies in patients. The primary aim of the Joslin DRC is to provide a facilitating framework for conducting multi-disciplinary basic and clinical research and to encourage the scientific development of young investigators. Special attention is paid to fostering rapid translation of basic research.
An analysis reveals that the branded form of a synthetic progestin for the prevention of recurrent preterm births costs 5,000 percent more than the compounded, made-to-order version of the medication despite having the same active ingredients and being clinically interchangeable.
Working with mouse cells, Harvard Medical School scientists have successfully recreated the segmentation clock that drives spine formation during embryonic development. Insights can illuminate normal spine development, understanding of spinal malformations such as scoliosis and spina bifida.
Wellesley Professor of American Studies Takes Readers “Behind the Laughs” of a Sometimes Brutal Business
The first large-scale study of ancient human DNA from sub-Saharan Africa opens a long-awaited window into the identity of prehistoric populations in the region and how they moved around and replaced one another over the past 8,000 years.
Largest study to date identifies gender-specific patterns of autism and related disorders occurrence among sibling pairs.
The brain plays an active and essential role much earlier than previously thought, according to new research from Tufts University scientists which shows that long before movement or other behaviors occur, the brain of an embryonic frog influences muscle and nerve development and protects the embryo from agents that cause developmental defects. Remarkably, the brain performs these functions while it is itself still developing, marking the earliest known events of the brain-body interface. In addition to identifying these essential instructive functions for the first time, the Tufts researchers successfully rescued defects caused by lack of a brain by using widely available, human-approved drugs.
Olin's 2017-2018 Senior Capstone in Engineering (SCOPE) program officially gets underway in September. Fourteen corporate partners have signed on this year to sponsor SCOPE teams made up of Olin seniors.
College and university students voted at a higher rate in 2016 than in 2012, according to a study from Tufts University’s Tisch College, which today released an analysis of the voting patterns of millions of students.
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