Many schizophrenic and depressed patients experience weight gain and type 2 diabetes in their quests for the life-changing benefits of a major class of antipsychotic drugs.
Hospitals are not off limits to tragic shooting events, and with these incidents on the rise in public places, more than half of the general public expects that physicians and nurses will protect them from harm if an active shooter event erupts while they’re in the hospital.
Researchers report encouraging preclinical results as they pursue elusive therapies that can repair scarred and poorly functioning heart tissues after cardiac injury. Scientists from the Cincinnati Children’s Heart Institute inhibited a protein that helps regulate the heart’s response to adrenaline, alleviating the disease processes in mouse models and human cardiac cells. Their data publishes Aug. 22 in the Journal of the American College of Cardiology.
UCLA researchers have developed a new approach that could eventually help young people respond better to treatment for acute lymphoblastic leukemia. The scientists discovered in mice that when the production of nucleotides -- also known as the building blocks of life -- is stopped, a "DNA replication stress response" is activated. The replication stress response is a cellular monitoring system that usually senses and resolves DNA damage, but instead allows cancer cells to survive.
The team, led by Dr. Caius Radu, a member of UCLA's Jonsson Comprehensive Cancer Center, used results of the study to devise a three-drug combination treatment regimen, which has proven to kill cancer cells and eradicate acute lymphoblastic leukemia in mouse models.
It seems like such a simple question: Do patients whose tumors shrink more in response to targeted treatment go on to have better outcomes than patients whose tumors shrink less? But the implications of a recent study demonstrating this relationship are anything but simple and could influence both the design of future clinical trials and the goals of oncologists treating cancer.
ROCHESTER, Minn. — Mayo Clinic researchers have identified a new cause of treatment resistance in prostate cancer. Their discovery also suggests ways to improve prostate cancer therapy. The findings appear in Nature Medicine.
Despite a decade-long call for simplification of clinical trials, the number of criteria excluding patients from participating in clinical trials for lung cancer research continues to rise.
Hackensack Meridian Health Raritan Bay Medical Center Foundation, a private, not-for-profit organization that has raised millions of dollars to support various health care services at Raritan Bay Medical Center, appointed Andrew Citron, M.D., director of the Division of Anesthesiology at the hospital, as chairman of the Board of Trustees. This is the first time in the Foundation’s history that a physician has served in this leadership role.
Pancreatic cancer is a particularly deadly form of disease, and patients have few options for effective treatment. But a new Yale Cancer Center study has identified a gene that is critical to pancreatic cancer cell growth, revealing a fresh target for new therapies.
With the arrival of two revolutionary treatment strategies, immunotherapy and personalized medicine, cancer researchers have found new hope — and a problem that is perhaps unprecedented in medical research.
Researchers at the Johns Hopkins University School of Medicine and the Mayo Clinic have compiled peer-reviewed evidence and crafted a guideline designed to help physicians and medical centers stop the use of a widely ordered blood test that adds no value in evaluating patients with suspected heart attack.
Imaging the movement of a virus demonstrates that single-particle X- ray scattering has the potential to shed new light on key molecular processes, like viral infection, when paired with powerful new algorithms.
UCLA researchers have discovered a new way to activate the stem cells in the hair follicle to make hair grow. The research, led by scientists Heather Christofk and William Lowry, may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy treatment.
NewYork-Presbyterian/Weill Cornell Medical Center has been verified as a Level I Adult and a Level II Pediatric Trauma Center by the American College of Surgeons’ Committee on Trauma (COT).