People aged 60-80 with low levels of the protein ABCA7 in the brain appear more likely to develop Alzheimer’s disease, according to a new study published in the Journal of Neuropathology & Experimental Neurology.
“AI-driven neuroimaging techniques have the potential to improve prediction models for Alzheimer’s progression and facilitate personalized treatment strategies,” says Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM).
“Are the risk factors for early onset Alzheimer’s the same as late onset?” asks Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM)
Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.
The test alone will not provide enough information to reach a diagnosis of memory problems/cognitive decline. Only a trained physician can do it.
Since 2012, September has been celebrated as World Alzheimer’s Month. Back then, and only eleven years ago, an average of 2 out of 3 people had little understanding of Alzheimer's disease and associated dementias.
“There is abundant evidence of a link between contact sports, such as football, and dementia later in life,” comments Domenico Pratico, M.D., Director of the Alzheimer’s Center at Temple University (ACT).
A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer’s disease. The new work was published online August 25 in the journal Cells.
A recent study has used Artificial Intelligence (AI) to reveal the remarkable potential of extra virgin olive oil (EVOO) in the fight against Alzheimer's disease (AD). Researchers combined AI technology, chemistry, and omics research to identify specific bioactive compounds in EVOO that show promising effects in treating and preventing AD.
A new approach could enhance memory and learning in individuals with Down syndrome by stabilizing a key component in the body's protein sorting system called the retromer complex.
A biomarker is a characteristic that can be measured and evaluated as an indicator of normal biological processes, pathogenetic processes, or pharmacologic responses to a therapeutic intervention. In the context of Alzheimer’s disease (AD), an AD biomarker indicates the presence or progression of the disease that may be altered by drug treatment, thereby demonstrating that it is hitting its target. Today, all clinical trials for Alzheimer’s disease utilize biomarkers of some form to assess whether the drug is actually affecting the disease in the brain.
The Lewis Katz School of Medicine created the Alzheimer’s Center at Temple from funds donated by Board of Trustees member Phil Richards earlier this month. Richards’s gift created the center and established the Scott Richards North Star Charitable Foundation Chair for Alzheimer’s Research.
Did you know that music might be able to connect you with your family members affected by Alzheimer's disease (AD) in a way that words cannot? Many studies have shown that music can evoke a response or a memory in people with Alzheimer's Disease.
The risk of side effects can rise if drugs are taken for conditions other than Alzheimer's disease (AD) treatment. Some sedatives and antidepressants can deteriorate cognitive function, make people drowsy and confused, and worsen cognitive impairment, which increases the risk of falls.
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