• share
• favorite_border

A new imaging technique helps UNC researchers study tiny, time-sensitive biological processes – the crucial underpinnings of human health and disease.

• share
• favorite_border

Modern Healthcare has named Dr. William L. Roper, CEO of UNC Health Care, dean of the UNC School of Medicine and vice chancellor for medical affairs at the University of North Carolina at Chapel Hill, to its annual list of the 100 Most Influential People in Health Care for 2017.

• share
• favorite_border

UNC Lineberger scientists led a multi-institution research team to identify key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

• share
• favorite_border

An antenna-like structure on cells, once considered a useless vestige, can cause defects in the brain’s wiring similar to what’s seen in autism, schizophrenia, and other disorders. In the lab, UNC scientists prevented defects by restoring signaling though these structures called primary cilia.

• share
• favorite_border

In the Journal of the National Cancer Institute, UNC Lineberger researchers published results of an analysis of approximately 1,000 invasive breast tumors. The study confirmed that young black women are more likely to have “triple negative,” or “basal-like,” breast cancers, a subtype that does not express any of the receptors for targeted biologic therapies. The study also identified variation by race within a clinical breast cancer type that has the greatest mortality disparity.

• share
• favorite_border

Researchers from UNC and NC State are developing a potential stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis – often-fatal conditions that affect tens of millions of Americans.

• share
• favorite_border

Researchers at the University of North Carolina at Chapel Hill have found Ebola RNA in the semen of survivors two years after infection. They are calling on the World Health Organization to update its guidelines on sexual transmission.

• share
• favorite_border

For the first time researchers at the University of North Carolina at Chapel Hill have developed an assay that can measure antigen production and clearance caused by a latency-reversing agent.

• share
• favorite_border

The National Institutes of Health has awarded the University of North Carolina more than $5.6 million to test a therapeutic vaccine for HIV. The study's principal investigator says the goals are to redirect and strengthen the immune response to the virus.

• share
• favorite_border

The protein TDP-43 is thought to cause muscle degeneration in patients with ALS. UNC and NC State researchers found that a specific chemical modification promotes TDP-43 clumping in animals. In muscle cells, scientists reversed protein clumping and prevented the sIBM-related muscle weakness.

• share
• favorite_border

Cancer drug Vorinostat given every 72 hours can awaken sleeping HIV in the body, says researchers at the University of North Carolina at Chapel Hill. However, it does not clear or deplete infection, meaning additional advances will be needed to achieve a cure.

• share
• favorite_border

Can the kinds of microbes colonizing the gut at age 1 predict later cognitive development? Findings from the UNC School of Medicine shed light on the surprising role of bacteria in how our brains develop during the first years of life.

• share
• favorite_border

UNC Health Care is one of only 27 systems in the United States to be recognized as a “Most Wired Advanced” health system by the American Hospital Association (AHA) for its use of information technology to improve patient care and clinical integration.

• share
• favorite_border

The William R. Kenan, Jr. Charitable Trust has awarded the School of Medicine at the University of North Carolina at Chapel Hill $1.5 million to establish interprofessional clinical experiences for health professions students in rural areas of the state, launching the UNC Rural Interprofessional Health Initiative (RIPHI).

• share
• favorite_border

In the journal Nature Nanotechnology, University of North Carolina Lineberger Comprehensive Cancer Center researchers report on strides made in the development of a strategy to improve the immune system's detection of cancer proteins by using “sticky” nanoparticles.

• share
• favorite_border

Technology invented in a laboratory in the UNC-NC State Joint Biomedical Engineering Program could soon mean painless diabetes testing and insulin injections for the nearly 400 million people with diabetes worldwide.

• share
• favorite_border

UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme called Set2 found in virtually all organisms other than bacteria. The basic science finding may have implications for understanding cancer development and how to halt it.

• share
• favorite_border

Researchers at the University of North Carolina School of Medicine announced the publication of results from a multi-site phase 2 clinical trial with brexanolone, an investigational medication, in the treatment of severe postpartum depression (PPD).

• share
• favorite_border

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

• share
• favorite_border

In a landmark study, UNC School of Medicine researchers have shown that blood glucose testing does not offer a significant advantage in blood sugar control or quality of life for type 2 diabetes patients who are not treated with insulin.