Now a group of scientists at the University of California, San Francisco (UCSF) has discovered that a tiny molecule in the fly’s brain called neuropeptide F governs this behavior—as the levels of the molecule change in their brains, the flies’ behavior changes as well.
Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).
Physical violence, sexual abuse and other forms of childhood and adult trauma are major factors fueling the epidemic of HIV/AIDS among American women. Scientists have known for years that traumatized women are at greater risk of becoming infected.
Ob-gyns are uniquely positioned to play a major role in reducing the effects of toxic chemicals on women and babies, according to an analysis led by University of California, San Francisco (UCSF) researchers.
UCSF’s School of Pharmacy ranked first in its field this year, while its School of Medicine tied for third place nationwide, according to a new survey conducted by U.S. News & World Report.
When QB3 opened its “garage” for bioscience entrepreneurs in 2006, detractors deemed it a quixotic venture, sure to fill with aspiring startups that would never leave campus.
In the war against obesity, one’s own fat cells may seem an unlikely ally, but new research from the University of California, San Francisco (UCSF) suggests ordinary fat cells can be reengineered to burn calories.
A drug once taken by people with HIV/AIDS but long ago shelved after newer, modern antiretroviral therapies became available has now shed light on how the human body uses its natural immunity to fight the virus—work that could help uncover new targets for drugs.
People with schizophrenia who completed 80 hours of intensive, computerized cognitive training exercises were better able to perform complex tasks that required them to distinguish their internal thoughts from reality.
Simultaneous targeting of two different molecules in cancer is an effective way to shrink tumors, block invasion, and stop metastasis, scientists at the University of California, San Francisco (UCSF) have found—work that may improve the effectiveness of combination treatments that include drugs like Avastin.
Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered how a protein “master regulator” goes awry, leading to metastasis, the fatal step of cancer.
The ability to anticipate future events allows us to plan and exert control over our lives, but it may also contribute to stress-related increased risk for the diseases of aging, according to a study by UCSF researchers.
A study of mothers and their young babies by neurologists at the University of California, San Francisco (UCSF) has shown that mothers who suffer migraine headaches are more than twice as likely to have babies with colic than mothers without a history of migraines.
When a person is experiencing a prolonged convulsive seizure, quick medical intervention is critical. With every passing minute, the seizure becomes harder to stop, and can place the patient at risk of brain damage and death. This is why paramedics are trained to administer anticonvulsive medications as soon as possible -- traditionally giving them intravenously before arriving at the hospital.
A UCSF stem cell study conducted in mice suggests a novel strategy for treating damaged cardiac tissue in patients following a heart attack. The approach potentially could improve cardiac function, minimize scar size, lead to the development of new blood vessels – and avoid the risk of tissue rejection.
Tenofovir, one of the most effective and commonly prescribed antiretroviral medications for HIV/AIDS, is associated with a significant risk of kidney damage and chronic kidney disease that increases over time, according to a study of more than 10,000 patients led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco (UCSF).
A new UCSF analysis has found that a state ballot initiative to increase the cigarette tax would create about 12,000 jobs and nearly $2 billion in new economic activity in California.
A new analysis published this week in the open-access journal PLoS ONE (Feb. 3, 2012) focused on a combined public health campaign in Western Province, Kenya led by the Swiss-based company Vestergaard Frandsen, the Kenyan Ministry of Health and the U.S. Centers for Disease Control and Prevention (CDC). The analysis looked at the cost effectiveness of simultaneously confronting the problems of HIV/AIDS, malaria, and diarrhea caused by waterborne pathogens.
Hormones shape our bodies, make us fertile, excite our most basic urges, and as scientists have known for years, they govern the behaviors that separate men from women. But how?
Scientists at the University of California, San Francisco (UCSF) have identified nearly 200 genes in the healthy prostate tissue of men with low-grade prostate cancer that may help explain how physical activity improves survival from the disease.
Sugar should be controlled like alcohol and tobacco to protect public health, according to a team of UCSF researchers, who maintain in a new report that sugar is fueling a global obesity pandemic, contributing to 35 million deaths annually worldwide from non-communicable diseases like diabetes, heart disease and cancer.
Clinical studies in U. S. And China show molecular test could more accurately guide treatment for people with lung cancer.
The UCSF Benioff Children’s Hospital has the best overall survival rates in the nation for bone marrow transplants, according to a recent independent review of 156 programs nationwide.
After people with low-grade glioma, a type of brain cancer, undergo neurosurgery to remove the tumors, they face variable odds of survival — depending largely on how rapidly the cancer recurs. Even though their doctors monitor the tumor closely with sophisticated imaging, it is difficult to determine with certainty whether cancer has returned in a more malignant state that requires aggressive treatment.
To probe the genetic secrets of one of the most common neurological diseases, more than 4,000 people with various forms of epilepsy will have their DNA decoded over the next five years in a study led by researchers at the University of California, San Francisco (UCSF) and several collaborating institutions.
Dogs with spinal cord injuries may soon benefit from an experimental drug being tested by researchers at the University of California, San Francisco (UCSF) and Texas A&M College of Veterinary Medicine & Biomedical Sciences — work that they hope will one day help people with similar injuries.
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells — even early-stage tumor cells — are tethered to scaffolding that helps to restrain any destructive tendencies. But scientists from the University of Helsinki, Finland, and from UCSF have identified a cleaver-wielding protein that frees some tumor cells, allowing them to further misbehave.
Drinking alcohol leads to the release of endorphins in areas of the brain that produce feelings of pleasure and reward, according to a study led by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco.
A large-scale national study suggests low to moderate use of marijuana is less harmful to users’ lungs than exposure to tobacco, even though the two substances contain many of the same components. This comprehensive study, led by UCSF and University of Alabama at Birmingham, collected data from more than 5,000 U.S. adults for more than 20 years.
UCSF Analysis Suggests Penny-Per-Ounce Tax on Sugary Beverages Would Prevent Heart Disease, Stroke and Diabetes and Save Billions in Healthcare Costs.
A new UCSF analysis of tobacco industry documents shows that Philip Morris USA manipulated data on the effects of additives in cigarettes, including menthol,obscuring actual toxicity levels and increasing the risk of heart, cancer and other diseases for smokers.
A tiny, freshwater flatworm found in ponds and rivers around the world that has long intrigued scientists for its remarkable ability to regenerate has now added a new wrinkle to biology.
In perhaps the most comprehensive survey of the inner workings of HIV, an international team of scientists led by researchers at the University of California, San Francisco has mapped every apparent physical interaction the virus makes with components of the human cells it infects—work that may reveal new ways to design future HIV/AIDS drugs.
A UCSF study shows a popular treatment for a potentially blinding eye infection is just as effective if given every six months versus annually. This randomized study on trachoma, the leading cause of infection-caused blindness in the world, could potentially treat twice the number of patients using the same amount of medication.
During his 23-year career, Steven Polevoi, MD, the medical director of the UCSF Emergency Department, has done everything from treat traumatic injuries to deliver babies. While medical emergencies occur throughout the year, Polevoi sees the winter season and its related overindulgence as a pivotal time for preventing emergencies by listening to our bodies.
As a woman ages, her chances of being diagnosed with a lower-risk breast tumor increase, according to a novel study led by UCSF which found that for women over 50, a substantial number of cancers detected by mammograms have good prognoses.
A large, international team of researchers led by scientists at the University of California, San Francisco has identified the gene that causes a rare childhood neurological disorder called PKD/IC, or “paroxysmal kinesigenic dyskinesia with infantile convulsions,” a cause of epilepsy in babies and movement disorders in older children.
The U.S. Department of Justice filed a proposed consent order today with a federal district court that finalizes requirements for three major tobacco companies to make internal documents public in accordance with an earlier ruling that the companies violated the Racketeer Influenced and Corrupt Organizations Act. The documents will be archived in UCSF’s Legacy Tobacco Documents Library (LTDL).
Throughout the interior spaces of humans and other warm-blooded creatures is a special type of tissue known as brown fat, which may hold the secret to diets and weight-loss programs of the future.
Adolescents hospitalized with anorexia nervosa who receive treatment based on current recommendations for refeeding fail to gain significant weight during their first week in the hospital, according to a new study by UCSF researchers.
A UCSF study suggests patients with chronic pain may experience greater relief if their doctors add cannabinoids – the main ingredient in cannabis or medical marijuana – to an opiates-only treatment. The findings, from a small-scale study, also suggest that a combined therapy could result in reduced opiate dosages.
UCSF and the Cell Technologies business of GE Healthcare Life Sciences have begun a unique collaboration aimed at overcoming the lack of blood-forming stem cells available to patients suffering from life-threatening diseases such as lymphoma, myeloma, leukemia or sickle cell anemia.
A cheaper laboratory test that helps guide anti-retroviral drug treatment for people with HIV/AIDS may be just as effective as a more sophisticated test, a group of international researchers has found – a discovery that could be particularly important in rural Africa.
The nation’s largest for-profit nursing homes deliver significantly lower quality of care because they typically have fewer staff nurses than non-profit and government-owned nursing homes.
Examining venom from a variety of poisonous snakes, a group of researchers at the University of California, San Francisco has discovered why the bite of one small black, yellow and red serpent called the Texas coral snake can be so painful.
In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn’t work, either because their tumors do not respond to the treatment at all, or because they develop resistance to it over time. Now researchers at the University of California, San Francisco (UCSF) have discovered the molecular basis for tamoxifen resistance and found a potential way to defeat it.
An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number of people in North America. It usually strikes young adults and is more common in women than in men.
A large, international clinical trial led by doctors at the University of California, San Francisco indicates that a vaccine to prevent anal cancer is safe and effective, according to a study reported in the October 27, 2011 issue of New England Journal of Medicine.
An 11-month-old partnership between UCSF and Pfizer, Inc., aimed at rapidly moving new therapies into human clinical trials, has selected its first projects for funding and joint development.
The California Institute for Quantitative Biosciences (QB3) has signed an agreement with the Johnson & Johnson Corporate Office of Science and Technology (COSAT) to fund University of California proof-of-concept research that brings innovative science to market.
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