Four University of Utah Health researchers will present their research and clinical trial findings, as well as engage in critical discussions around cardiovascular medicine at the 2017 European Society of Cardiology Congress in Barcelona, Spain.
Rena D’Souza, D.D.S., Ph.D., Professor of Dentistry at the University of Utah Health received a grant from the National Institutes of Health (NIH) to build on her past research to characterize the genetics that prevent tooth formation and develop therapies to reverse this process.
Like the rest of the body, the brain loses flexibility with age, impacting the ability to learn, remember, and adapt. Now, scientists at University of Utah Health report they can rejuvenate the plasticity of the mouse brain, specifically in the visual cortex. Published today in PNAS, the study shows that manipulating a single gene triggers the shift, revealing it as a target for new treatments to recover the brain’s youthful potential.
Kensaku Kawamoto, Ph.D., has been appointed to a 3-year term on the U.S. Health Information Technology (HIT) Advisory Committee.
Researchers grow protein crystals on the International Space Station to find antidotes for nerve agents used in conflict zones.
Scientists have had limited success at identifying specific inherited genes associated with prostate cancer. Researchers at University of Utah Health studied prostate cancer patients with multiple cancer diagnoses to identify genetic mutations that may influence cancer treatment and cancer risk.
The American Heart Association (AHA) awarded investigators at University of Utah Health $3.7 million to conduct collaborative research to prevent and treat congenital heart disease. U of U Health is one of four groups across the country to join the AHA’s Strategically Focused Research Network (SFRN) for children.
“Yarraman flu is a virus quickly infecting the US…” The mock announcement was enough to make readers worry. But when the name of the hypothetical illness was changed to “horse flu”, readers reported being less motivated to get a vaccine that would prevent them from contracting the illness. Based on a survey of 16,510 participants from 11 countries, the findings show that the way health information is communicated, matters. The multi-institutional investigation appeared in Emerging Infectious Diseases.
Antibiotics were the wonder drug of the 20th century, but bacteria evolved resistance. According to the CDC, more than 2 million people in the U.S. develop MDR infections every year. Researchers at Univ. of Utah developed a rapid screen to pair existing FDA-approved drugs to combat MDR infections.
Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. Scientists have found up to 30 percent of adult ALL patients have what’s called a Philadelphia chromosome, where two segments of chromosomes have aberrantly fused together. Adult ALL patients exposed to standard treatments often see high relapse rates, and treatment-related deaths remain high. But researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered new science, published this week in the journal Leukemia, that could provide better therapeutic options for patients.
This automated machine could reduce a surgical procedure from two hours to two and a half minutes by replacing hand drills for one type of complex cranial surgery.
Our world seems to grow smaller by the day as biodiversity rapidly dwindles, but Mother Earth still has a surprise or two up her sleeve. An international team of researchers were the first to investigate a never before studied species a giant, black, mud dwelling, worm-like animal. The findings will be published online in the Apr. 17 issue of the Proceedings of the National Academy of Sciences.
Scientists report a significant step toward combatting two degenerative brain diseases that chip away at an individual’s ability to move, and think. A targeted therapy developed by scientists at University of Utah Health slows the progression of a condition in mice that mimics a rare disease called ataxia. In a parallel collaborative study, led by researchers at Stanford University, a nearly identical treatment improves the health of mice that model Amyotrophic Lateral Sclerosis (ALS), commonly called Lou Gehrig’s disease.
The University of Utah is one of just five institutions in the world to be awarded a $2.5 million grant to purchase a state of the art cryo-electron microscope (cryo-EM), the Beckman Foundation announced today. The microscope, which will be able to visualize the structure of proteins and DNA at an atom-by-atom scale, will be installed in the Crocker Science Center, currently under construction. The microscope’s resolution is fine enough to see details such as the double-helix and ladder structure of DNA, said biochemistry professor Wesley Sundquist.
Two screening tests often used to try to predict which pregnant women are likely to deliver prematurely aren’t effective in low-risk women, according to a national collaborative study of more than 10,000 women, led by clinician-researchers at University of Utah Health Sciences and Intermountain Healthcare. Researchers found that neither transvaginal cervical measurement or fetal fibronectin tests, used separately or together, adequately predicts preterm birth. The findings are published in March 14 issue of the Journal of the American Medical Association.
During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health. While most studies have focused on bacteria, the dominant microbial inhabitants in the gut, scientists at University of Utah Health Sciences used mouse studies to show the role of yeast in aggravating the symptoms of Inflammatory Bowel Disease (IBD). Their work suggests that allopurinol, a generic drug already on the market, could offer some relief.
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