Like locking the door but opening windows, an immune checkpoint therapy temporarily slows glioblastoma progression but fails to establish an effective anti-tumor microenvironment and appears to increase molecular interactions inhibiting long-term immune response.
A new study led by researchers at UCLA Health has found that cognitive behavioral therapy (CBT-I) prevented major depression, decreasing the likelihood of depression by over 50% as compared to sleep education therapy in adults over the age of 60 with insomnia.
Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.
An experimental technology developed ” technology being developed by researchers at the UCLA Samueli School of Engineering and the David Geffen School of Medicine at UCLA uses images of suspicious-looking lesions and quickly produces a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis — including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.
Research by UCLA Fielding School's UCLA Center for Health Policy Research, led by Dr. Ninez Ponce, Fielding School professor of health policy and management, found that Californians have varied their COVID-19 risk reduction based on their test results
Now, in a study published in the journal Cell Reports Medicine, UCLA researchers report a critical step forward in the development of an “off-the-shelf” cancer immunotherapy using human stem cell-derived invariant natural killer T cells, rare but powerful immune cells that could potentially be produced in large quantities, stored for extended periods and safely used to treat a wide range of patients with various cancers.
A UCLA study has found that young adults who have experienced discrimination have a higher risk for both short- and long-term behavioral and mental health problems.
Two of the University of California’s nationally ranked medical centers, UCLA and UCSF, have partnered with the California Department of Health Care Services (DHCS) and Office of the California Surgeon General (CA-OSG) to lead a multi-campus initiative addressing the impact of Adverse Childhood Experiences (ACEs) and other causes of toxic stress on health.
New UCLA research finds that misinformation and politicization, awareness of past injustices involving medical research, and fears about the inequitable distribution of vaccines all contributed to hesitancy to be vaccinated among Los Angeles' People of Color.
Dr. Robert Chin, a radiation oncologist with UCLA Jonsson Comprehensive Cancer Center, will describe recent research on personalized treatment for HPV-associated oropharyngeal cancer – particularly for patients with an inherited variant KRAS gene – during a panel discussion on radiation and cancer biology at ASTRO, the annual meeting of the American Society for Radiation Oncology.
In a phase 2 single-institution study, UCLA Jonsson Comprehensive Cancer Center researchers found that dose-equivalent preoperative radiation therapy for extremity/trunk soft tissue sarcoma delivered in five days rather than over the conventional five weeks produced similar benefits and treatment side effects.
An individual patient data (IPD) meta-analysis of randomized, controlled clinical trials provides strong evidence for the addition of androgen deprivation therapy (ADT) to definitive radiotherapy (RT) for the treatment of prostate cancer, with the projection that adding ADT to the treatment of 10-15 men would prevent the development of distant metastasis in one man.
A new study led by researchers at UCLA Health has found that women over the age of 50 who had breastfed their babies performed better on cognitive tests compared to women who had never breastfed. The findings, published in Evolution, Medicine and Public Health, suggest that breastfeeding may have a positive impact on postmenopausal women’s cognitive performance and could have long-term benefits for the mother’s brain.
A program offered by UCLA Health’s intensive care units is providing meaningful and compassionate support for dying patients and their families, despite the challenges brought about by COVID-19.
Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.
A new study from UCLA finds a visit from human-controlled robot encourages a positive outlook and improves medical interactions for hospitalized children.
Health care personnel who received a two-dose regimen of Pfizer–BioNTech vaccine had an 89% lower risk for symptomatic illness than those who were unvaccinated. For those who received the two-dose regimen of the Moderna vaccine, the risk was reduced by 96%.
Cinco de los sistemas de salud sin fines de lucro más grandes del condado de Los Ángeles incluyendo hospitales, clínicas e instalaciones en toda la región, anunciaron la campaña más reciente para su coalición bettertogether.health.
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