Latest News from: Wistar Institute

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Newswise: BioBuzz Workforce Champion Award goes to Wistar’s New Biomedical Technician Training Program
Released: 14-Dec-2022 2:25 PM EST
BioBuzz Workforce Champion Award goes to Wistar’s New Biomedical Technician Training Program
Wistar Institute

The Wistar Institute Biomedical Technician Training (BTT) Program was awarded Workforce Champion of the Year in the 3rd Annual 2022 BioBuzz Awards. The program is a collaborative that includes The Wistar Institute, West Philadelphia Skills Initiative, Iovance Biotherapeutics, PIDC, and others.

   
Newswise: “The London Patient” Adam Castillejo Speaks at William Way Community Center to Spread Hope for a Future HIV  Cure
Released: 20-Oct-2022 2:05 PM EDT
“The London Patient” Adam Castillejo Speaks at William Way Community Center to Spread Hope for a Future HIV  Cure
Wistar Institute

The Wistar Insitute, William Way Community Center, Philadelphia FIGHT, BEAT-HIV Delaney Collaboratory, Philadelphia Foundation, and The Penn Center for AIDS Research are proud to announce that “The London Patient” Adam Castillejo will take part in a panel conversation and Q&A on Wednesday, October 26 from 5 to 8 pm

Newswise: Wistar Scientists Identify Link Between Mitochondria and Pancreatic Cancer Risk
12-Oct-2022 11:15 AM EDT
Wistar Scientists Identify Link Between Mitochondria and Pancreatic Cancer Risk
Wistar Institute

In a research paper published in PLOS ONE, The Wistar Institute's Dario C. Altieri, M.D., alongside national and international collaborators, distinguish a specific gene signature indicative of mitochondrial reprogramming in tumors that correlates with poor patient outcome.

Newswise: Wistar’s Dr. Amelia Escolano Earns NIH Director’s New Innovator Award
Released: 4-Oct-2022 10:00 AM EDT
Wistar’s Dr. Amelia Escolano Earns NIH Director’s New Innovator Award
Wistar Institute

The National Institutes of Health has awarded Amelia Escolano, Ph.D., assistant professor in The Wistar Institute’s Vaccine & Immunotherapy Center, the 2022 NIH Director’s New Innovator Award.

Newswise: Wistar Scientists Identify Key Biomarkers that Reliably Predict Response to Immune Checkpoint Inhibitor Therapy for Melanoma 
Released: 19-Sep-2022 9:00 AM EDT
Wistar Scientists Identify Key Biomarkers that Reliably Predict Response to Immune Checkpoint Inhibitor Therapy for Melanoma 
Wistar Institute

Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research out of The Wistar Institute now provides evidence of novel, reliable biomarkers that predict therapy response using advanced computer technology.

Newswise: The Wistar Institute Welcomes Michele A. Schiavoni, New Vice President of Communications &  Marketing
Released: 8-Sep-2022 12:55 PM EDT
The Wistar Institute Welcomes Michele A. Schiavoni, New Vice President of Communications &  Marketing
Wistar Institute

The Wistar Institute is pleased to announce the appointment of Michele A. Schiavoni, M.S., as Vice President of Communications & Marketing, in a central leadership role that will bolster the visibility of the Institute’s ambitious biomedical research science initiatives and programs advancing the organization’s newly launched Bold Science // Global Impact Capital Campaign.

   
Newswise: The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils Halts Cancer Progression and Metastasis
Released: 7-Sep-2022 11:05 AM EDT
The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils Halts Cancer Progression and Metastasis
Wistar Institute

Researchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at Jubilant Therapeutics Inc. have uncovered a novel mechanism by which protein arginine deiminase 4 (PAD4) in neutrophils promotes cancer progression. The paper also found that inhibition of this function of PAD4 reduces primary tumor growth and metastasis and enhances checkpoint inhibitor treatments.

Newswise: Wistar Receives Merit Extension from the National Cancer Institute
Released: 2-Aug-2022 10:35 AM EDT
Wistar Receives Merit Extension from the National Cancer Institute
Wistar Institute

The National Cancer Institute (NCI) has granted a Merit Extension Award to The Wistar Institute’s Ellen and Ronald Caplan Cancer Center totaling more than $5 million.

Newswise: Wistar Scientists Reveal New Function of Enzyme ADAR1 Linking it to Age-Related Diseases via a Role Independent of RNA-editing During Aging
18-Jul-2022 8:05 AM EDT
Wistar Scientists Reveal New Function of Enzyme ADAR1 Linking it to Age-Related Diseases via a Role Independent of RNA-editing During Aging
Wistar Institute

Published today in Nature Cell Biology, Wistar scientists revealed a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence and its potential implications in tissue aging.

Newswise: The Wistar Institute Names Gelvina Rodriguez Stevenson, Esq., as Vice President, General Counsel, Secretary and Government Relations
Released: 13-Jul-2022 10:00 AM EDT
The Wistar Institute Names Gelvina Rodriguez Stevenson, Esq., as Vice President, General Counsel, Secretary and Government Relations
Wistar Institute

The Wistar Institute announces the appointment of Gelvina Rodriguez Stevenson, Esq., as vice president, general counsel, secretary and government relations.

Newswise: Collaboration Advances DNA-delivered Antibodies to Prevent COVID-19
7-Jul-2022 9:20 AM EDT
Collaboration Advances DNA-delivered Antibodies to Prevent COVID-19
Wistar Institute

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

Newswise: Jonathan Lax Memorial Award Lecture Streams Globally
Released: 24-Jun-2022 9:35 AM EDT
Jonathan Lax Memorial Award Lecture Streams Globally
Wistar Institute

Wistar announces that for the first time it will globally stream its 26th Annual Jonathan Lax Memorial Award Lecture, celebrating 26 years of providing state-of-research updates to the community, on Tuesday, June 28 from 9:30 to 11:00 a.m. EST.

Newswise: Wistar Scientists Identify Novel Therapeutic Approach to Re-Activate Immune Response Against Tumors
Released: 21-Jun-2022 10:00 AM EDT
Wistar Scientists Identify Novel Therapeutic Approach to Re-Activate Immune Response Against Tumors
Wistar Institute

Wistar scientists identified that inhibiting therapeutic target KDM5A boosts a person’s immune response to tumors.

   
Newswise: Wistar Institute Launches Bold Science // Global Impact Capital Campaign to Rechart the Future of Human Health
Released: 16-Jun-2022 10:05 AM EDT
Wistar Institute Launches Bold Science // Global Impact Capital Campaign to Rechart the Future of Human Health
Wistar Institute

Wistar Institute announces its Bold Science // Global Impact Capital Campaign to support a five-year plan that sets out Wistar’s roadmap for accelerated progress to drive breakthroughs in biomedical science and technology and educate and train the next generation of innovators.

   
Newswise: Wistar Scientists Move HIV Vaccine Research Forward by Developing an Immunogen that Produces Tier-2 Antibodies—the Kind That Matter for Combatting HIV
3-Feb-2022 3:55 PM EST
Wistar Scientists Move HIV Vaccine Research Forward by Developing an Immunogen that Produces Tier-2 Antibodies—the Kind That Matter for Combatting HIV
Wistar Institute

Wistar Institute scientists take a promising step in the direction of developing an HIV vaccine that uses a unique native-like trimer to develop Tier-2 neutralizing antibodies—the kind that matter for combatting HIV—in mice for the first time.

Newswise: Novel Nanoparticle SARS-CoV-2 Vaccine Combines Immune Focusing and Self-assembling Nanoparticles to Elicit More Potent Protection
Released: 1-Feb-2022 11:35 AM EST
Novel Nanoparticle SARS-CoV-2 Vaccine Combines Immune Focusing and Self-assembling Nanoparticles to Elicit More Potent Protection
Wistar Institute

The first generation of COVID-19 vaccines have been highly effective, but also have limitations. Now Wistar scientists have developed a more targeted vaccine that, in animal studies, shows stronger, broader, and more durable protection in a single, low dose.

   
Newswise: Wistar Scientists Identify Therapeutic Target for Epstein-Barr Virus
17-Jan-2022 5:00 AM EST
Wistar Scientists Identify Therapeutic Target for Epstein-Barr Virus
Wistar Institute

A new study by Wistar researchers has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

Newswise: The Wistar Institute and Stanford Medicine to Begin Phase 2 Clinical Trial of VK-2019 in Patients with Epstein-Barr Virus (EBV)-Positive Advanced Nasopharyngeal Carcinoma
Released: 5-Jan-2022 9:35 AM EST
The Wistar Institute and Stanford Medicine to Begin Phase 2 Clinical Trial of VK-2019 in Patients with Epstein-Barr Virus (EBV)-Positive Advanced Nasopharyngeal Carcinoma
Wistar Institute

Wistar announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

Newswise: Fox Chase Cancer Center, The Wistar Institute Announce Opening of Phase 1 Clinical Trial of Anticancer Drug Candidate
Released: 2-Dec-2021 11:20 AM EST
Fox Chase Cancer Center, The Wistar Institute Announce Opening of Phase 1 Clinical Trial of Anticancer Drug Candidate
Wistar Institute

Fox Chase Cancer Center has opened an investigator-initiated, phase 1 clinical trial to evaluate the safety and efficacy of gamitrinib in patients with advanced cancer.

29-Nov-2021 6:00 PM EST
Wistar Scientists Identify Genes Critical to Protecting Ovarian Cancer from the Immune System
Wistar Institute

Scientists at The Wistar Institute have identified two genes that play a critical role in protecting ovarian cancer from the immune system.



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