A report from the Autism Intervention Research Network on Physical Health (AIR-P), a multi-site collaboration housed within UCLA Health’s Department of Medicine, highlights the intersection of autism, poverty and race/ethnicity and their compounding impact on health and health care.
The rate of overdose deaths among U.S. teenagers nearly doubled in 2020, the first year of the COVID pandemic, and rose another 20% in the first half of 2021 compared with the 10 years before the pandemic, even as drug use remained generally stable during the same period.
For a recent six-year period, the injury rate for riders of electric scooters in one section of Los Angeles was higher than the national rates for riders of motorcycles, bicycles and cars, and pedestrians.
A new study led by researchers at UCLA has shown that a specialized primary care medical home improved the care and treatment of patients with serious mental illness, resulting in better mental health-related quality of life.
A new study led by UCLA Health scientists shows highly creative people’s brains appear to work differently from others', with an atypical approach that makes distant connections more quickly by bypassing the “hubs” seen in non-creative brains.
The National Institute of Mental Health has renewed its support for UCLA’s collaborative Center for HIV Identification, Prevention and Treatment Services, or CHIPTS, with a five-year, $7.5 million grant.
psychedelics may find new, legitimate roles in treatment for anxiety, depression, stress disorders, addiction, and other mental and behavioral health problems. But ensuring they do requires developing rigorous, standardized methods to study and apply the results, according to a new report.
The Dementia Care Study (D-CARE), a nation-wide clinical trial assessing the effectiveness of different approaches to caring for people with Alzheimer’s disease and other dementias, has reached its recruitment goal by enrolling 2,176 persons living with dementia and their caregivers
Researchers say the challenges of treating long COVID are amplified by a critical issue: we do not know what constitutes long COVID or how to formally diagnose it, an issue that is further exacerbated by limited research data of varying quality and consistency.
Researchers at UCLA Health have found that Housing First, a national program to provide housing and support for homeless persons, was effective in helping homeless veterans access housing and remain in their homes five years after it was implemented.
In 2020, the first year of the COVID-19 pandemic, the rate of drug overdose deaths among Black Americans surpassed that of whites for the first time since 1999 — a sharp reversal of the situation a decade earlier, when rates were twice as high for whites as for Blacks.
Analyzing breast-cancer tumors with artificial intelligence has the potential to improve healthcare efficiency and outcomes, but doctors should proceed cautiously, according to a new editorial in JAMA Health Forum co-written by Dr. Joann G. Elmore, a researcher at the UCLA Jonsson Comprehensive Cancer Center.
UCLA Health, in partnership with BioscienceLA and UCLA Biodesign, has launched a new accelerator at the intersection of health equity and technology. Aimed at supporting long-term community health resilience and improvements in the aftermath of the COVID-19 pandemic, the UCLA Health TechQuity Accelerator seeks to bridge clinical excellence and innovation for diverse patient populations.
UCLA researchers presented today the first case of a U.S. woman living with HIV-1 that is in remission after she received a new combination of specialized stem cell transplants for treatment of acute myeloid leukemia (AML). The oral abstract was presented at CROI 2022, the Conference on Retroviruses and Opportunistic Infections.
An interim analysis of an ongoing Phase III study from UCLA Jonsson Comprehensive Cancer Center indicates that using magnetic resonance imaging (MRI) to guide precisely-focused high-dose radiation treatment for prostate cancer reduced side effects associated with the treatment. The findings are being presented at the 2022 ASCO Genitourinary (GU) Cancers Symposium in San Francisco, Calif.
A newly launched UCLA Space Medicine Fellowship, the first of its kind in the U.S., aims to develop the next generation of flight surgeons who will support the health, safety, and well-being of human space flight and planetary expeditions.
A team led by UCLA researchers will receive a multi-million dollar grant to study why some people suffer from a devastating fungal infection called Valley Fever, while others suffer seemingly no impact from the disease.
Investigators from UCLA Jonsson Comprehensive Cancer Center have identified a germline biomarker signature that successfully predicts which patients will suffer serious side effects that occur in up to three in 10 patients on anti-PD1/PDL1 therapy, a promising new approach to treating cancer.
Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington’s disease, providing new clues to the disease and giving researchers a powerful new tool to test new therapies engaging multiple targets.
Neuroscientists at the David Geffen School of Medicine at UCLA in collaboration with scientists at UC Berkeley have discovered that visual stimulation not only guides the way brain cells connect, but actually influences the types of cells that form in the first place – something that was thought to be genetically programmed.
A cost analysis of the controversial new Alzheimer’s disease drug aducanumab shows that ancillary care services account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.
Some of the most socioeconomically disadvantaged patients — those with Medicaid or Medicare-Medicaid dual eligibility insurance — were far less likely than those with other insurance plans to return to using outpatient services at rates approaching normal, pre-pandemic levels.
Researchers in a multi-institution study led by UCLA Health call for more research as well as customized treatments, education and support to empower women living with Parkinson’s disease to address their unmet medical needs.
The UCLA Center for SMART Health and Hearst Health, have announced a partnership to offer the Hearst Health Prize awarding data science initiatives that demonstrate a positive impact on health outcomes.
A new study led by researchers at UCLA Health finds no evidence of SARS-CoV-2 transmission through breastmilk.
Researchers led by a team from the UCLA Jonsson Comprehensive Cancer Center used prostate cancer patients’ DNA to create a model that appears to predict who will have side effects from radiation.
A new study finds that while young and healthy mice show clear differences between daytime and nighttime body temperature rhythms, in older and diseased animals the difference essentially disappeared.
A study in mice led by UCLA researchers shows that removing chemical messengers in the brain that are involved in both wakefulness and addiction may make withdrawal from opioids easier and help prevent relapse.
In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells. The advance could move scientists a step closer to being able to reduce the amount of virus, or even eliminate it, from infected people.
New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.
Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular “crosstalk” in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.
UCLA Jonsson Comprehensive Cancer Center researchers led the development of a melanoma model of drug resistance, enabling them to study structures and dynamics resulting in intrachromosomal and extrachromosomal changes that support resistance in cancer cells.
Researchers from UCLA Jonsson Comprehensive Cancer Center and UCLA Health will participate in dozens of presentations at the annual meeting of the American Society of Hematology (ASH), held virtually and in person in Atlanta Dec. 11-14. A few of these are highlighted here.
Researchers at UCLA Jonsson Comprehensive Cancer Center led a large international study providing what is believed to be the first evidence (albeit indirect) that a recently approved imaging technique improves risk-stratification and long-term prognostic capabilities for patients with high-risk prostate cancer whose conventional imaging showed only localized disease.
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.
A combination of vaccination and naturally acquired infection appears to boost the production of maximally potent antibodies against the COVID-19 virus, new UCLA research finds.
Among HIV-positive black and Latino men who have sex with men, the use of methamphetamine combined with intimate partner violence may increase the risk for developing chronic diseases such as cardiovascular disease and other disorders.
Like locking the door but opening windows, an immune checkpoint therapy temporarily slows glioblastoma progression but fails to establish an effective anti-tumor microenvironment and appears to increase molecular interactions inhibiting long-term immune response.
A new study led by researchers at UCLA Health has found that cognitive behavioral therapy (CBT-I) prevented major depression, decreasing the likelihood of depression by over 50% as compared to sleep education therapy in adults over the age of 60 with insomnia.
Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.
An experimental technology developed ” technology being developed by researchers at the UCLA Samueli School of Engineering and the David Geffen School of Medicine at UCLA uses images of suspicious-looking lesions and quickly produces a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis — including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.
Research by UCLA Fielding School's UCLA Center for Health Policy Research, led by Dr. Ninez Ponce, Fielding School professor of health policy and management, found that Californians have varied their COVID-19 risk reduction based on their test results
Now, in a study published in the journal Cell Reports Medicine, UCLA researchers report a critical step forward in the development of an “off-the-shelf” cancer immunotherapy using human stem cell-derived invariant natural killer T cells, rare but powerful immune cells that could potentially be produced in large quantities, stored for extended periods and safely used to treat a wide range of patients with various cancers.
A UCLA study has found that young adults who have experienced discrimination have a higher risk for both short- and long-term behavioral and mental health problems.
Two of the University of California’s nationally ranked medical centers, UCLA and UCSF, have partnered with the California Department of Health Care Services (DHCS) and Office of the California Surgeon General (CA-OSG) to lead a multi-campus initiative addressing the impact of Adverse Childhood Experiences (ACEs) and other causes of toxic stress on health.
New UCLA research finds that misinformation and politicization, awareness of past injustices involving medical research, and fears about the inequitable distribution of vaccines all contributed to hesitancy to be vaccinated among Los Angeles' People of Color.
Dr. Robert Chin, a radiation oncologist with UCLA Jonsson Comprehensive Cancer Center, will describe recent research on personalized treatment for HPV-associated oropharyngeal cancer – particularly for patients with an inherited variant KRAS gene – during a panel discussion on radiation and cancer biology at ASTRO, the annual meeting of the American Society for Radiation Oncology.
In a phase 2 single-institution study, UCLA Jonsson Comprehensive Cancer Center researchers found that dose-equivalent preoperative radiation therapy for extremity/trunk soft tissue sarcoma delivered in five days rather than over the conventional five weeks produced similar benefits and treatment side effects.
An individual patient data (IPD) meta-analysis of randomized, controlled clinical trials provides strong evidence for the addition of androgen deprivation therapy (ADT) to definitive radiotherapy (RT) for the treatment of prostate cancer, with the projection that adding ADT to the treatment of 10-15 men would prevent the development of distant metastasis in one man.
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