A team led by Dr. Brigitte Gomperts at UCLA has developed a “scar in a dish” model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.
A new study from scientists at UCLA helps explain why some people with advanced cancer may not respond to one of the leading immunotherapies, PD-1 blockade, and how a new combination approach may help overcome resistance to the immunotherapy drug.
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.
UCLA Jonsson Comprehensive Cancer Center researchers have developed a new automated method for testing hundreds of molecules at a time to find out which ones block cancer cells from consuming glucose — the sugars they need to spread and grow.
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions
UCLA study finds even a short-term visit to a severely polluted city is bad for your health
A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell – nucleotide metabolism – to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.
It's Lung Cancer Awareness Month and there are few stories about women who are diagnosed with lung cancer. Here’s one story about a 42-year-old, non-smoking Mom of two who was surprised with a lung cancer diagnosis last Thanksgiving. The story also features tips from a UCLA pulmonologist on the signs and symptoms of lung cancer.
Ziva Cooper, research director of the UCLA Cannabis Research Initiative, has been awarded a $3.5 million grant from the National Institutes of Health to conduct a five-year study assessing the pain-relieving effects of cannabis and cannabinoids, the chemicals in the cannabis plant.
UCLA has received $27.2 million from the National Institutes of Health to spearhead the new phase of an initiative to enhance the diversity of the U.S.’s biomedical workforce.
Dr. Linda Liau, chair of neurosurgery at the David Geffen School of Medicine at UCLA, has been appointed chair of the American Board of Neurological Surgery. She is the first woman to lead the organization in its 80-year history.
UCLA researcher Sandra Loo was a principal investigator on the study that led to FDA approval of the first non-drug ADHD treatment. In this Q&A, Loo discusses the device and its potential in ADHD treatment.
Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards totaling more than $18 million from the California Institute for Regenerative Medicine, the state’s stem cell agency.
The prostate cancer program at the UCLA Jonsson Comprehensive Cancer Center and UCLA Health has been awarded an $8.7 million Specialized Program of Research Excellence, or SPORE, grant from the National Cancer Institute.
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new biomarker using a noninvasive imaging method that tracks mitochondrial activity in lung tumors.
When researchers from UCLA and the Laureate Institute for Brain Research in Tulsa, Oklahoma, wanted to test an app they created to measure body image perception, they went to the body image experts — fashion models.
Nearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban used over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding.
Thiazide diuretics demonstrate better effectiveness and cause fewer side effects than ACE inhibitors as first-line antihypertensive drugs, according to a report published Oct. 24 in The Lancet. Marc A. Suchard, MD, PhD, professor of biostatistics at the UCLA Fielding School of Public Health served as lead author.of the study.
A UCLA-led study finds that, with the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury.
A new study examining the role that star-shaped brain cells called astrocytes play in Huntington’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.
This month, the UCLA Jonsson Cancer Center has launched a pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial that will attack cancer cells by simultaneously recognizing two targets – CD19 and CD20 – that are expressed on B-cell lymphoma and leukemia.
A new study led by UCLA researchers, have found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma, one of the deadliest and most aggressive forms of skin cancer.
Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men’s genomes — the complete set of genetic material inherited from one’s parents — that predict how an individual person’s prostate cancer will grow. The finding suggests that predicting how a person’s cancer will evolve may lie in their inherited DNA.
A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.
Scientists from the UCLA Integrated Substance Abuse Programs will lead a $25 million National Institutes of Health study testing treatments, including the use of telemedicine, to help fight the opioid epidemic in rural America.
UCLA researchers have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice.
In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals.
Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health.
A UCLA-led study has found that using three-dimensional virtual reality models to prepare for kidney tumor surgeries resulted in substantial improvements, including shorter operating times, less blood loss during surgery and a shorter stay in the hospital afterward.
Physician-scientist Dr. Dennis Slamon, has been awarded the 2019 Lasker-DeBakey Clinical Medical Research Award for the groundbreaking development of breast cancer drug Herceptin (trastuzumab), a life-saving therapy for women with HER2-positive breast cancer.
UCLA has been awarded a grant from the U.S. Department of Commerce’s Economic Development Administration to create a regional hub for the development of medical technology and digital health tools.
Dozens of countries lack important legal protections against children doing work that could be harmful or interfere with their education, according to a study by the WORLD Policy Analysis Center at UCLA.
In a new book edited by a professor from the UCLA Fielding School of Public Health, academicians and community organizers explain how public health practitioners can identify and address racism.
A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants.
Researchers developed a drug delivery system that can break through the blood-brain barrier in mice.
A comprehensive dementia care program staffed by nurse practitioners working within a health system improves the mental and emotional health of patients and their caregivers.
A Veterans Health Administration program that added mental health specialists, care managers or both in primary care clinics significantly improved access to mental health and primary care services to veterans with behavioral health needs. The practice also resulted in 9% higher average annual costs for each patient.
UCLA researchers have developed an artificial intelligence system that could help pathologists read biopsies more accurately and to better detect and diagnose breast cancer.
A research team has identified dozens of genes, including 16 new genes that increase the risk of autism spectrum disorder.
The prostates of older mice contain more luminal progenitor cells — cells capable of generating new prostate tissue — than the prostates of younger mice, UCLA researchers have discovered.
Researchers from the UCLA Jonsson Comprehensive Cancer Center undertook a head-to-head comparison of two imaging techniques and have concluded that prostate-specific membrane antigen imaging is more effective in detecting the location of the prostate cancer recurrence.
UCLA hospitals rank #1 in L.A. and California, #6 in nation. For 30th consecutive year, U.S. News & World Report places UCLA on national honor roll reserved for top medical centers.
A UCLA-led research team has found that giving mice antibiotics for 10 days prior to a liver transplant leads to better liver function after the surgery -- then they came across data that it also works in humans. It's all linked to the antibiotics' effect on the microbiome.
Using an ultra-sensitive and high-throughput isolation technology, UCLA researchers were able to characterize and identify the neoantigens driving the antitumor responses in a patient treated with anti-PD-1 blockade and isolate the T cell receptors responsible for such effect.
New research suggests that 32% of children up to the age of 3 years who were exposed to the Zika virus during the mother’s pregnancy had below-average neurological development. Also, fewer than 4% of 216 children evaluated had microcephaly —a smaller-than-normal head that is one of the hallmarks of the mosquito-borne disease. The heads of two of those children grew to normal size over time, the researchers reported.
An interdisciplinary team of UCLA scientists has found that small cell neuroendocrine cancers from a range of tissues have a common molecular signature and share drug sensitivities with blood cancers.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right