The Howard Hughes Medical Institute has created the Janelia Farm Research Campus to fill a need for a scientific community that promotes and rewards collaborative, interdisciplinary research.
Researchers in the West African country of Guinea have discovered the first African hantavirus, a type of rodent-borne virus that can cause life-threatening infections in humans.
A commonly prescribed blood pressure medication may provide the first ray of hope in preventing potentially deadly complications of Marfan syndrome, a genetic disease that weakens the structural meshwork of blood vessels.
Teaching often takes a back seat to research at leading universities. Determined to change that, Howard Hughes Medical Institute has named 20 leading research scientists to energize the undergraduate science classroom. Each will receive $1 million over four years.
Enzymes that can harm the brain immediately after a stroke may actually be beneficial days later. The findings could change the way stroke is treated, extending the window for effective treatment from a couple of hours to a couple of weeks.
Researchers have demonstrated that they can nearly eliminate production of infectious prion proteins in livestock by using an innovative approach based on RNA interference (RNAi).
Scientists have used the mathematics of information theory to confirm that the songs of humpback whales have their own complex syntax containing the elements of language.
The glow emitted by a variety of sea coral helped Russian scientists harness the protein that generates the light to create a tiny fluorescent tag that responds to visible light. The tag should help researchers follow individual proteins as they dart around inside living cells.
Researchers studying a lethal canine virus and a related human virus have determined why the canine virus was able to spread quickly from cats to dogs. Their findings provide a new understanding of the molecular factors that enable viruses to jump from one species to another.
Using computer-simulated HIV protease molecules, HHMI scientists have identified a potential new drug target for drug-resistant HIV infection.
Researchers in Argentina have determined that night blindness is a new clinical symptom of Chagas disease. They found that the immune systm of individuals with the tropical disease can shut down a key reaction in the retina, causing night blindness.
For decades, scientists have wondered how living organisms manufacture the essential vitamin B12. Now, using laundry whitener and dirt-dwelling bacteria - everyday ingredients of an undergraduate science experiment - researchers may have found a major clue to solving the mystery.
Howard Hughes Medical Institute wants to shorten the time it takes to translate basic science discoveries into new medical treatments. As a first step, HHMI has awarded $10 million to fund 13 innovative graduate programs that will introduce Ph.D. students to the world of clinical medicine.
An innovative way of categorizing myosin, one of three molecular motors that produce movement within cells, has dramatically increased the amount of information available about these essential proteins, laying the groundwork for development of new treatments for many medical conditions.
Scientists in India, led by a Howard Hughes Medical Institute international research scholar, have identified five key genes that enable the bacterium that causes TB to acquire the iron it needs to sustain growth and promote infection.
An HHMI-supported undergraduate's research reveals the neurological mechanism used to enter torpor, a hibernation-like state. The finding could help doctors treat stroke patients more effectively.
In a study of the travels of the malaria parasite Plasmodium through mammalian tissue, researchers found the parasites developing in an unexpected place: the lymph nodes. The findings could help scientists develop more effective vaccines.
Researchers have identified the job of one of the most common DNA-damage response proteins, an enzyme that has puzzled scientists every since it was discovered. DinB DNA polymerase turns out to be a specialist at accurate replication of a particular kind of damaged DNA.
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