A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments.
Researchers at Mount Sinai School of Medicine have identified a common compound in the modern diet that could play a major role in the development of abdominal obesity, insulin resistance, and type 2 diabetes.
Latrepirdine, which failed in U. S. Clinical trials of alzheimer’s disease, is showing new potential in an animal model.
Finding provides new drug development opportunity in this hard-to-treat disease.
Researchers at Mount Sinai School of Medicine, the University of Manchester, and the MD Anderson Cancer Center have found a new role for an oncogenic signaling pathway in embryonic stem cell (ESC) self-renewal and in reprogramming adult cells into an ESC-state, which will aid in the development of future cancer therapies.
An international team of scientists led by researchers at Mount Sinai School Medicine have discovered that a drug that had previously yielded conflicting results in clinical trials for Alzheimer’s disease effectively stopped the progression of memory deterioration and brain pathology in mouse models of early stage Alzheimer’s disease.
Predictors of disease severity in human papillomavirus-derived head and neck cancer, tobacco use, and the dramatic benefits of robotic surgery in people with head and neck cancer are among landmark research presented by Mount Sinai School of Medicine at the Eighth International Conference on Head and Neck Cancer.
Researchers from Mount Sinai School of Medicine have developed a new computational method that will help organize scientific data, making it easier for scientists to identify and prioritize genes, drug targets, and connections between drugs.
A team of researchers have found that schizophrenia or bipolar disorder seen in parents or siblings was associated with increased risk of autism spectrum disorder (ASD). The study was published online by Archives of General Psychiatry on Monday, July 2.
A patient registry is proving invaluable in cataloging the clinical features, symptoms, severity, and outcomes of fibromuscular dysplasia (FMD), a non-inflammatory vascular disease that can cause narrowing of arteries in the carotid (neck) and renal (kidney) arteries, which can result in headache, strokes, and aneurysms. Registry data revealed that 91 percent of patients are women diagnosed in the prime of their lives. As a result, physicians are developing best practices that can lead to early diagnosis and treatment with the goal of improved outcomes and fewer adverse vascular events.
A lifestyle that features fresh foods and limited use of products likely to contain environmental chemicals has been shown to reduce exposure to endocrine-disrupting chemicals (EDCs), such as BPA and phthalates, in a small population study. EDCs are linked to a number of adverse health complications including neuro-developmental delays, behavioral issues and fertility problems. They are produced by the millions of pounds per year and found extensively in a range of products that contain certain plastics.
The Center for Minimally Invasive and Robotic Surgery at The Mount Sinai Medical Center—a pioneer in robotic surgery—now offers the procedure to patients with sleep apnea, whose obstructive breathing prevents them from sleeping normally.
A new delivery method for levodopa/carbidopa, a common dual-drug Parkinson’s disease (PD) regimen, significantly improved the duration of the drugs’ effectiveness in people with advanced PD.
The Mount Sinai Medical Center is the first institution in New York State to use in the clinical setting a newly approved imaging technique to detect Alzheimer’s disease (AD) in people who are cognitively impaired. Until now, physicians have been limited in their ability to diagnose AD, guided almost exclusively by a patient’s mental and behavioral symptoms and family history.
David Samadi, MD, Vice-Chair of Urology at Mount Sinai School of Medicine, knows that many men put off caring for their health, even when they have a family. But just a loving nudge from his family can help keep Dad on track for long-term prostate health, prostate cancer prevention, and prostate cancer awareness.
Researchers from Mount Sinai School of Medicine developed a cancer model built in the fruit fly Drosophila, then used it to create a whole new approach to the discovery of cancer treatments. The result is an investigational compound AD80 that precisely targets multiple cancer genes. Tested in mouse models, the drug proved far more effective and less toxic than standard cancer drugs, which generally focus on a single target. This is the first time that whole-animal screening has been used in a rational, step-wise approach to polypharmacology. The study appears online today in the journal Nature.
New York magazine named 129 Mount Sinai physicians to its “Best Doctors” list, more than any individual hospital in New York City. The recent issue also lists 59 additional doctors who serve at hospitals within Mount Sinai’s affiliate network.
Researchers from Mount Sinai School of Medicine are pioneering new ultrasound techniques that provide the first characterization of multidirectional blood flow in the heart. By focusing on fluid dynamics – specifically, the efficiency with which blood enters and exits the heart’s left ventricle – the researchers believe they can detect heart disease even when traditional measures show no sign of trouble.
Mount Sinai School of Medicine researchers will present several landmark studies, including data on treatment trends in late-stage cancer, a promising multiple myeloma vaccine, and predictive models of soft tissue sarcomas, prostate and bladder cancer, at the 2012 American Society of Clinical Oncology (ASCO) meeting June 1-5, 2012 in Chicago.
Researchers at Mount Sinai School of Medicine in New York have found new clues in the pathogenesis of skull and skin birth defects associated with a rare genetic disorder, Beare-Stevenson cutis gyrata syndrome (BSS).
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