Credit: Kota Kagohashi, et al. The Journal of Immunology. February 5, 2024
The inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO mice exhibited less demyelination—loss of the myelin sheath that surrounds nerves—when compared with those of WT mice (bottom panels). (Kota Kagohashi, et al. The Journal of Immunology. February 5, 2024)