Credit: ANDREW YOO and ZHAO SUN/Washington University
Researchers at Washington University School of Medicine in St. Louis have developed a way to study aged neurons in the lab without a brain biopsy, allowing them to accurately model the effects of aging in the development of late-onset Alzheimer's disease. Shown is a 3D reconstruction of amyloid beta plaque deposition (green) between neurons (red) grown in the lab. These neurons were transformed from human skin cells taken from patients with late-onset Alzheimer's disease.