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Fight, Flight, or Freeze: Animal Study Connects Fear Behavior, Rhythmic Breathing, Brain Smell Centers

There’s increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion. Now researchers have added neurons associated with the olfactory system to the connection between behavior and breathing....
20-Apr-2018 2:05 PM EDT Add to Favorites


Putting Proteins in Their Proper Place

A host of nuclear RNA-binding proteins, when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including FTD and ALS. Clumps that form from these disease proteins are composed of sticky fibrils that damage nerve...
19-Apr-2018 4:00 PM EDT Add to Favorites


Penn Medicine’s Carl June, MD, Named One of Time Magazine’s Most Influential People in the World

TIME named University of Pennsylvania cancer and HIV gene therapy pioneer Carl June, MD, to the 2018 TIME 100, its annual list of the 100 most influential people in the world.
19-Apr-2018 11:05 AM EDT Add to Favorites

Three Solutions to Maximize the Clinical Benefit and Affordability of Targeted Cancer Drugs

A group led by the Abramson Cancer Center of the University of Pennsylvania has proposed three solutions to maximize the clinical benefit and affordability of targeted cancer drugs.
16-Apr-2018 9:00 AM EDT Add to Favorites

Abramson Cancer Canter Studies Show Promise of Immunotherapy Combinations, Including CAR T

As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the...
16-Apr-2018 9:00 AM EDT Add to Favorites

Could Statins Ease Deadly Heart Condition in Rare Neuromuscular Disease?

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich’s ataxia (FA), a widely used cholesterol-lowering drug increased a precursor of HDL (high-density lipoprotein), the “good...
17-Apr-2018 10:05 AM EDT Add to Favorites

Penn Researcher Co-Directs National Lung Cancer Screening Center

Researchers from the Perelman School of Medicine at the University of Pennsylvania, along with the Institute for Health Research at Kaiser Permanente Colorado, Kaiser Permanente Hawaii, the Henry Ford Health System in Detroit, and Marshfield Clinic...
17-Apr-2018 10:05 AM EDT Add to Favorites

Penn Study Finds Relationship between PTEN Loss, Potential for Immune Response in BRCA 1/2-Deficient Ovarian Cancer

The protein known as phosphatase and tensin homolog (PTEN) is frequently mutated or affected by cancer as tumors develop. Now a new study from the Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania shows PTEN may...
15-Apr-2018 9:05 AM EDT Add to Favorites

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