Researchers from PNNL have helped colleagues at OHSU identify lipid molecules required for Zika infection in human cells. The specific lipids involved could also be a clue to why the virus primarily infects brain tissue.
For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses.
In a new study, published June 5, 2020, in the Journal of Experimental Medicine, scientists at La Jolla Institute for Immunology (LJI) shows that antibodies against JEV are “cross-reactive” and can also recognize Zika virus. Unfortunately, these antibodies can actually make Zika cases more severe.
Even after heroic medical and societal efforts finally break the back of the current COVID-19 pandemic, the global sigh of relief may not last long. The chilling reality is that viral threats are growing more common. And they’re getting deadlier.
Zika virus is capable of replicating and spreading infectious particles within the outermost cells lining the vaginal tract, according to new research.
People who rate themselves as highly knowledgeable about a new infectious disease threat could also be more likely to believe they don’t know enough, a new study suggests.
When disease epidemics and outbreaks occur, conspiracy theories often emerge that compete with the information provided by public health officials.
Researchers at Washington University School of Medicine in St. Louis have found that the strain of Zika that circulated in Brazil during the microcephaly epidemic that began in 2015 was particularly damaging to the developing brain.
A virus spreading in China has the world on alert.
In Nature, a team led by U.S. Department of Energy (DOE) Joint Genome Institute (JGI) researchers uncovered a broad diversity of large and giant viruses that belong to the nucleocytoplasmic large DNA viruses (NCLDV) supergroup, expanding virus diversity in this group 10-fold from just 205 genomes.
An international team of scientists has synthetically engineered mosquitoes that halt the transmission of the dengue virus. The development marks the first engineered approach in mosquitoes that targets the four known types of dengue, improving upon previous designs that addressed single strains.
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.
A device to quickly capture and identify various strains of virus has been developed, according to researchers at Penn State and New York University.
Researchers in China have discovered how a Zika virus protein reshapes its host cell to aid viral replication. The study, which will be published December 23 in the Journal of Cell Biology, reveals that the viral protein NS1 converts an interior cellular compartment called the endoplasmic reticulum (ER) into a protective region where the virus can survive and replicate. Blocking this process could be a novel therapeutic strategy to treat patients infected with Zika or similar viral pathogens, such as the yellow fever and dengue viruses.
The UM School of Medicine's Contract awarded by the National Institute of Allergy and Infectious Diseases could fund up to $201 Million in influenza research over seven years.
In the game against an essentially unlimited pool of virus threats, humanity is seriously outmatched. In order to shift the balance, scientists need to change the game.
Researchers at Vanderbilt University Medical Center (VUMC) are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.
An innovative graphene-based film helps shield people from disease-carrying mosquitos, according to a new study funded by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.
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