Columbia University will award the 2016 Louisa Gross Horwitz Prize to Howard Cedar, PhD, and Aharon Razin, PhD, of the Hebrew University of Jerusalem, and Gary Felsenfeld, PhD, of the National Institutes of Health.
New research may help those with advanced mastocytosis and possibly many more people. Mastocytosis is a rare disease of the immune system in which the body produces too many abnormal mast cells. Mast cells control allergic and inflammatory responses. Research on a new drug shows that it may prolong life significantly and improve quality of life.
Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington’s disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse the mutated gene effects responsible for HD.
Hard labor might be the very thing we try to avoid on Labor Day. But our cells and their components don’t have the luxury of taking a day off. We at NIH's National Institute of General Medical Sciences give a shout out to some of these tireless cellular workers.
Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.
A paper published in ACS Nano, one of the top nanotechnology journals in the world, explores this topic. “Modeling and Analysis of Intercalant Effects on Circular DNA Conformation” focuses on the effect of the intercalating agent ethidium bromide (a mimic for many chemotherapy drugs) on the tertiary structure of DNA.
Using a new, lightning-fast camera paired with an electron microscope, University of Maryland School of Medicine scientists have captured images of one of the smallest human proteins to be “seen” with a microscope.
University of North Carolina Lineberger Comprehensive Cancer Center researchers, by tracking a molecular marker that has been shown to increase in white blood cells as people age, have uncovered clues that suggest that stem cell transplant is linked to a marked increase in the “molecular age” of these immune cells in a group of patients with blood cancer.
Research uncovers true properties of rare radioactive metal that could provide key to targeted cancer drugs.
The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds.
Scientists discovered that the major developmental function of heterochromatin – a form of tight DNA packaging found in chromosomes – is likely the suppression of virus-like DNA elements known as transposons, which can copy and paste themselves throughout the genome, potentially causing diseases.
Scientists invent a multi-view microscope that doubles the resolution of images without exposing them to an increased amount of light or prolonging the imaging process.
The National Cancer Institute (NCI) awarded the University of Minnesota an $8.2 million Physical Sciences in Oncology Center (PS-OC) grant over the next five years to develop a cell migration simulator that will predict how cancer cells spread in the body leading to invasion and metastasis.
Roger Tsien, PhD, co-winner of the 2008 Nobel Prize in chemistry and professor of pharmacology, chemistry and biochemistry at University of California San Diego School of Medicine for 27 years, died August 24 in Eugene, Ore. He was 64.
The National Institutes of Health have awarded Dr. Evgeny Pavlov, assistant professor of basic science and craniofacial biology at the New York University College of Dentistry , a $1.8M, five-year grant to study the phenomenon known as the “Mitochondrial Permeability Transition” to prevent strokes and heart attacks.
Developing blood cells are caught in tugs of war between competing gene regulatory networks before finally deciding what type of cell to become, according to a study published Aug. 31 in Nature. Researchers at Cincinnati Children’s Hospital Medical Center report that as developing blood cells are triggered by a multitude of genetic signals firing on and off, they are pulled back and forth in fluctuating multi-lineage states before finally becoming specific cell types.
Insoo Hyun has proposed a framework for addressing ethical questions surrounding potentially revolutionary research on part-human, part-animal embryos, which can be produced when human stem cells are transplanted into animal embryos.
A clinical trial using stem cells to treat people with recent spinal cord injuries has cleared two key safety hurdles, and been given approval to expand the therapy to a larger group of patients with a much higher dose of cells.
Sanford Burnham Prebys Medical Discovery Institute (SBP), the Johns Hopkins University School of Medicine, the Salk Institute for Biological Studies, and the University of Michigan will embark on a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced.
Berkeley Lab researchers linked the overexpression of 14 genes related to cell division to cancer patients' prognosis and response to specific treatments. The findings could be used to develop a biomarker that doctors and patients use to make better informed decisions in clinical settings.
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