Feature Channels: Genetics

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In a review published online today in AERA Open, a peer-reviewed journal of the American Educational Research Association, researchers from Stanford University and the University of Cambridge warn that—as the predictive power of genes tied to learning and educational outcomes increases and access to genetic data expands—researchers, educators, and policymakers must be cautious in how they use such data, interpret related findings, and, in the not-too-distant future, apply genetics-informed student interventions.

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The research, by the Genetic Investigation of ANthropometric Traits (GIANT) consortium, identifies genetic variants associated with obesity that are central to developing targeted interventions that can reduce the risks of chronic illnesses to which obesity contributes in significant ways.

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Researchers studying genome of Great White Shark to see what secrets may be applicable to the human condition

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From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn’t clear. Using new technology to reveal the 3D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations.

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Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules.

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Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

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A young squirrel lucky enough to take over territory from an adult male squirrel is like a teenager falling into a big inheritance, according to a new University of Guelph study.

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Proper development of the fetal penis requires not just testosterone from the testes, but a second hormone produced by other tissues, including the placenta, according to a new study publishing February 14 in the open-access journal PLOS Biology from Paul Fowler of the University of Aberdeen

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Researchers using proteomics and mouse genetics to understand the protein makeup of HDL find that it's a complicated mix of inherited and environmental factors. Their work may help understand HDL's functions beyond carrying cholesterol.

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St. Jude Children’s Research Hospital scientists have completed one of the largest studies yet designed to advance understanding of why Hispanic children are more likely to develop leukemia and less likely to survive

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Las células madre pluripotentes inducidas son las laboriosas obreras de muchos proyectos de medicina regenerativa y empiezan como células diferenciadas que, a través de la exposición a un complejo conjunto de mezclas genéticas, se reprograman para convertirse en células madre pluripotentes.

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According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. However, traditional non-invasive prenatal tests for the condition are unreliable or carry risks for the mother and fetus. Now, researchers have developed a sensitive new biosensor that could someday be used to detect fetal Down syndrome DNA in pregnant women’s blood. They report their results in the ACS journal Nano Letters.

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Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

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Using super-sensitive microscopic imaging, a team of scientists made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish through narrow openings without springing a leak.

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The quality of your marriage could be affected by your genes, according to new research conducted at Binghamton University, State University of New York.

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Newly approved gene therapy is offering a hopeful outlook to some patients with inherited eye disease including a 7-year-old who received treatment at Michigan Medicine.

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For people with inherited eye disease, genetic findings can often guide patients toward applicable clinical trials. or sight-preserving gene therapy.

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A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent. The discovery shows that Staphyloccocus aureus can acquire additional genes that promote infections and antibacterial resistance and may open new paths for the development of antibacterial drugs, according to a study in the Journal of Biological Chemistry.

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A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.