Feature Channels: Liver Disease

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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The latest research on plants brought to you by Newswise.

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Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer—at an early enough stage that cure is possible. Their work was published online in the peer-reviewed journal Hepatology.

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The latest research and expert commentary on the monkeypox outbreak.

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The American Association for the Study of Liver Diseases (AASLD) Foundation, the largest medical society supporter of liver disease research and training in the United States, today announced its combined investment of over $1.5 million in Research and Career Development Awards, Abstract Awards, Emerging Liver Scholars (ELS) Program for medical residents and its new Emerging Liver Advanced Practice Provider (APP) Program. The 2022 award recipients — selected from a highly competitive applicant pool — demonstrate both exceptional aptitude and deep interest in liver disease research and treatment. Their work will further advance the mission of the AASLD Foundation and hepatology as a medical specialty.

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In mouse studies, UC San Diego researchers find that excess alcohol consumption alters gut microbiome but latter is not directly or significantly linked to liver disease.

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UT Southwestern will lead a multisite initiative funded by the National Cancer Institute (NCI) to identify biomarkers to improve risk assessment and early detection of hepatocellular cancer (HCC), the most common form of liver cancer, among patients with cirrhosis.

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Below are some of the latest articles that have been added to the Food Science channel on Newswise, a free source for journalists.

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The August issue of The American Journal of Gastroenterology highlights new clinical science, including a brand new ACG clinical guideline for the diagnosis and treatment of patients with gastroparesis.

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New research led by UCLA Jonsson Comprehensive Cancer Center investigators suggests that new technology in development may lead to a better way to detect early-stage hepatocellular carcinoma (HCC).

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Data published in Cell Metabolism on liver cancer’s rapid growth which leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

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Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.

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Physicians and researchers from UK HealthCare's Transplant Center and the University of Kentucky Markey Cancer Center conducted a study of patients over the age of 70 with a type of liver cancer called hepatocellular carcinoma (HCC) and how the outcomes of ablative treatments compare to liver transplants. The findings were published in the May 2022 issue of the Journal of the American College of Surgeons.

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People with sedentary lifestyles and unhealthy sleep behaviors could develop fatty liver disease, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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In mouse studies, UC San Diego researchers report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage.

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Clinical advances include treating hematologic cancers with effective targeted therapies, circulating tumor DNA as a biomarker for recurrence with colorectal liver metastases, and using magnetic resonance imaging (MRI) to guide surgical decisions for patients with lateral pelvic lymph node metastases in rectal cancer. Laboratory findings offer new understanding of the pancreatic cancer immune microenvironment, melanoma cell states, TP53 mutation status in acute myeloid leukemia (AML), and potential targets for metastatic prostate cancer and GNAS-mutant colorectal cancer.

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Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.