Using spatial analysis of tissue samples, Cedars-Sinai investigators have identified patterns that could predict whether patients with the most common type of ovarian cancer will experience early relapse after treatment.
Opioid dependence in Scotland remains high but largely stable, according to a new University of Bristol-led analysis published in Addiction today [18 April] and by Public Health Scotland. The study is the first to estimate the number of people dependent on opioid drugs (such as heroin), and who are in or could benefit from drug treatment, among Scotland’s population since 2015/2016 estimates were published.
Microbiologists do not fully understand how bacteria’s genes relate to their life strategies. Now, by analyzing large DNA sequencing datasets from around the globe, researchers discovered a new way of categorizing the dominant life strategies of soil bacteria based on their genes. This technique allowed the researchers to link different life strategies with specific climate and soil conditions.
The harder your brain works at your job, the less likely you may be to have memory and thinking problems later in life, according to a new study published in the April 17, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Increased warming in tundra ecosystems is resulting the release of carbon into the atmosphere through ecosystem respiration, contributing additionally to climate change. A recent meta-analysis published Nature revealed factors that contribute to ecosystem respiration, including soil nitrogen concentration, pH and ratio of carbon to nitrogen.
A detailed reconstruction of climate during the most recent ice age, when a large swath of North America was covered in ice, provides information on the relationship between CO2 and global temperature. Results show that while most future warming estimates remain unchanged, the absolute worst-case scenario is unlikely.
Mountain chickadees have among the best spatial memory in the animal kingdom. New research identifies the genes at play and offers insight into how a shifting climate may impact the evolution of this unique skill.
In patients undergoing colonoscopy to screen for colorectal cancer, deeper sedation using the anesthetic drug propofol may improve detection of "serrated" polyps — a type of precancerous lesion that can be difficult to detect, reports a study in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists (ASA).
By utilizing the power of electronic medical records, researchers from UC San Diego are uncovering the genetics of tobacco use, which would help scientists discover new ways to stop occasional tobacco use from evolving into tobacco use disorder.
For patients undergoing carpometacarpal (CMC) joint surgery for treatment of thumb osteoarthritis, the use of online video instruction for postoperative hand therapy is associated with outcomes similar to in-person therapy visits – while substantially reducing travel time and distance, reports a clinical trial in The Journal of Bone & Joint Surgery.
Microscopic studies of rodent incisors revealed nano-sized pockets of iron-rich material that form a protective shield, a finding that could improve human dentistry, say researchers in ACS Nano.
Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year. A team of KIT researchers has now identified a new cell type in blood vessels responsible for vascular growth.
Prolonged droughts followed by sudden bursts of rainfall – how do desert soil bacteria manage to survive such harsh conditions? This long-debated question has now been answered by an ERC project led by microbiologist Dagmar Woebken from the Centre for Microbiology and Environmental Systems Science (CeMESS) at the University of Vienna.
A new study led by the University of Portsmouth has used 30 years of data from the Office for National Statistics to distinguish between how much people spent on essential and non-essential goods and services.
The protein Asc-1 serves as the gateway (either for entry or exit) for fundamental amino acids involved in cognitive processes. A new study now unveils its structure and mechanism of action.
New research shows that despite Matildas soccer mania gripping the nation during the 2023 World Cup, women footballers in general face an uphill battle gaining widespread acceptance in Australia and overcoming entrenched sexism.
Research shows schools have increasingly stepped in as a fourth emergency service and are now the biggest source of charitable food and household aid for families struggling with the cost-of-living crisis.
Nearly everyone with Down syndrome will eventually develop Alzheimer's disease. Researchers at Washington University School of Medicine in St. Louis have discovered that Alzheimer’s disease starts earlier and moves faster in people with Down syndrome.
A group of researchers based at UC San Diego and Rady Children's Institute have advanced the understanding of how the cerebral cortex develops by tracing the lineage of certain brain cells.
New research in the April 2024 issue of JNCCN—Journal of the National Comprehensive Cancer Network showcases the feasibility of improving early detection and prevention for pancreatic cancer.
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.
Scientists at Sanford Burnham Prebys have now identified promising real-world links between common HIV drugs and a reduced incidence of Alzheimer’s disease. The study, led by Jerold Chun, M.D., Ph.D., was published in Pharmaceuticals.
Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection of this cancer type, which currently does not have a reliable screening method.
Heart failure patients may one day be able to restore cardiac function with medications that revive the body’s ability to regenerate heart muscle, a novel study at UT Southwestern Medical Center suggests.
In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.
The Martinot Lab at Cummings School of Veterinary Medicine at Tufts University, where faculty and students have been researching the mpox virus in endometrial tissues to raise awareness of the potential increased risk of mpox virus for women.
In recent advancements, flexible pressure sensors have been developed to mimic human skin's sensitivity, significantly benefiting fields like interactive technologies, health monitoring, and robotics. These innovations leverage a variety of microstructural strategies, including pyramidal, dome, wrinkle, and layered structures, for enhanced sensitivity and durability. Despite their potential, current designs often involve complex manufacturing processes. Addressing these challenges, new approaches aim to simplify sensor fabrication while broadening their pressure detection capabilities and stress tolerance, pushing the boundaries of sensor technology towards more efficient and versatile applications.
Researchers from Analysis Group, a global leader in health economics and outcomes research (HEOR), have coauthored the first large-scale study that revealed racial disparities in treatment, survival, and access to care among patients with metastatic castration-sensitive prostate cancer (mCSPC) since the first novel hormonal therapy was approved in 2018.
By merging the findings of several diet-brain studies, researchers hope to better understand the association between dietary intake and cognitive decline or impairment.
Florida is projected to lose 3.5 million acres of land to development by 2070. A new study highlights how Florida can buffer itself against both climate change and population pressures by conserving the remaining 8 million acres of “opportunity areas” within the Florida Wildlife Corridor (FLWC), the only designated statewide corridor in the U.S.
Nurse-legislator offers eight specific steps nurses can take to position themselves as confident advocates ready to engage in policy discussions and influence policymakers. The article is part of a symposium in AACN Advanced Critical Care about political engagement for nurses and advanced practice nurses.
In their ongoing quest to develop a range of methods for managing plasma so it can be used to generate electricity in a process known as fusion, researchers at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) have shown how two old methods can be combined to provide greater flexibility.
A research team has elucidated the role of polyploidy in the evolution and breeding of vegetable crops, leveraging advanced sequencing technologies to dissect the genetic and epigenetic nuances of polyploids.
A research team has made process in understanding benzylisoquinoline alkaloids (BIAs) in lotus (Nelumbo nucifera), highlighting their presence in various tissues and their potential for novel drug development.
A research team has shed light on the early morning 'golden hours' as a pivotal time for achieving optimal water use efficiency (WUE) in crops, revealing that plants can maintain lower transpiration rates and higher photosynthetic activity under favorable light conditions and minimal vapor pressure deficit (VPD).
A research team delves into the role of the Target of Rapamycin (TOR) signalling pathway in plant grafting, emphasizing its role in regulating seedling vigor, graft junction healing, and shoot-to-root communications.
Aalto University researchers adapt a novel force measurement technique to uncover the previously unidentified physics at play at the thin air-film gap between water droplets and superhydrophobic surfaces.
According to a research team led by palaeontologists from the University of Vienna, the net-like leaf veining typical for today’s flowering plants developed much earlier than previously thought, but died out again several times.
The chloroplast (cp) is critical for various biological functions in plants, such as photosynthesis and stress responses, with its genome offering simpler analysis and sequencing due to its size and reduced homologous influence.
New research has given insight into the resilience and recovery of businesses in two South Australian regions following a major bushfire event and disruptions caused by the COVID-19 pandemic.
A research team has unveiled 20 β-galactosidase (BGAL) genes within the longan genome, highlighting their crucial roles in embryogenic development and heat stress adaptation.
A research team reviews the critical relationship between the accumulation of anthocyanins and organic acids in fruits, highlighting how these factors influence fruit color and consumer appeal through changes in vacuolar pH.
The transition from vegetative to reproductive stages in plants involves both internal and external cues, with grapevines (Vitis vinifera L. cv. Pixie) presenting a unique case.
The research unveils the superior tolerance of 'Shuzhen No.1', a novel Citrus junos rootstock, to flooding, alkaline, and freezing stresses over commonly used rootstocks. Grafted scions on 'Shuzhen No.1' exhibited enhanced growth and vigor, making it a promising candidate for future citrus cultivation.
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