Engineers at the University of California San Diego have developed biomimetic bone tissues that could one day provide new bone marrow for patients needing transplants.
The American College of Rheumatology today praised Congressional leaders for reaching a spending deal that provides a significant boost in federal funding for medical research.
Some types of sarcomas elicit a greater immune response than others, which sheds light on how immunotherapy could be used for this connective-tissue cancer, according to a new study in Cancer. Photos, video available: http://www.fredhutch.org/en/news/media-relations/bios-photos/pollack-seth.html
Pablo G. Castañeda, MD, an internationally renowned expert in pediatric and adolescent hip conditions, has joined Hassenfeld Children’s Hospital of New York at NYU Langone as its new chief of pediatric orthopedic surgery. Prior to joining, he practiced for 10 years in Mexico City.
Using CRISPR technology, a team of researchers led by Farshid Guilak, PhD, at Washington University School of Medicine in St. Louis, rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions.
A new clinical trial at Baylor Scott & White Research Institute is exploring a novel treatment option for patients with multiple myeloma, a type of cancer formed in bone marrow plasma cells that is considered incurable.
In a preclinical study in mice and human cells, researchers report that selectively removing old or 'senescent' cells from joints could stop and even reverse the progression of osteoarthritis.
Bone mineral density, an indicator of bone strength, typically increases with regular exercise, acting as a protective mechanism against bone fractures and osteoporosis. But a new study suggests that the extended, high-intensity training sessions of elite athletes could reverse beneficial bone changes. Researchers from Brock University in Canada will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2017 in Chicago.
Winner of the Sanford J. Larson, MD, PhD, Award, Daipayan Guha, MD, presented his research, Optical Topographic Imaging for Intra-Operative Three-Dimensional Navigation in the Cervical Spine: Accuracy Validation and Initial Clinical Feasibility, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
After nearly 40 years of advancing the field of osteopathic medicine and blazing trails for women and minorities, Barbara Ross-Lee, D.O., is retiring as vice president for Health Sciences and Medical Affairs at New York Institute of Technology (NYIT), an institution she served for 16 years in multiple leadership roles. A longtime advocate for advancing medical treatment in underserved communities and an expert in national health care policy, Ross-Lee has inspired thousands of medical students to pursue careers in osteopathic medicine.
Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.
Why are women at higher risk of complications after total hip or knee replacement surgery? An increased rate of hypersensitivity to the metals contained in joint implants might be a contributing factor, suggests a study in the April 19 issue of The Journal of Bone & Joint Surgery. The journal is published by Wolters Kluwer.
The decision by U.S. Citizenship and Immigration Services (USCIS) to suspend premium processing of H-1B visas for doctors, specialists, and other medical professionals poses an immediate and dangerous threat to chronically ill patients living in rural and underserved communities throughout the United States, warned the American College of Rheumatology (ACR) today in a letter to the Trump Administration.
Using 3-D models of a patient’s foot, investigators at Cedars-Sinai have found that the three leading procedures for treating heel deformities do not adequately correct the debilitating problem. Investigators used 18 identical 3-D prints of a single patient’s heel to evaluate the most common techniques for treating Charcot-Marie-Tooth disease (CMT), a genetic neuromuscular disease that kills the long nerves in the hands and feet.
In what is known to be the largest study on bone metastases in thyroid cancer, researchers at the University of Michigan Comprehensive Cancer Center found that patients with follicular and medullary thyroid cancer had the highest rate of cancer-related bone lesions and fractures and an increased risk of death.
As the World Health Organization steps up its efforts to eradicate a once-rampant tropical disease, a University of Washington study suggests that monitoring, and potentially treating, the monkeys that co-exist with humans in affected parts of the world may be part of the global strategy.
A new study published in the Journal of the American Medical Association (JAMA), adds to a growing body of recent research supporting the use of spinal manipulative therapy (SMT) as a first line treatment for acute low back pain, according to the American Chiropractic Association (ACA).
Hematologist-oncologist Ahmad Samer Al-Homsi MD, MBA, will lead a new bone marrow transplantation program at NYU Langone’s Perlmutter Cancer Center for treating blood-borne cancers, including leukemia, lymphoma and multiple myeloma, and utilize transplantation as an adjunct to immunotherapy for solid tumors.
UT Southwestern Medical Center researchers discovered a small protein named Myomixer essential for the formation of skeletal muscle – findings that could eventually help treat genetic diseases such as muscular dystrophy and other myopathies.
ASA recommends the Oregon Health Authority’s (OHA) Health Evidence Review Committee (HERC) reconsider its initial ruling that eliminates coverage for epidural steroid spinal injections for patients suffering from chronic back pain in the state’s health programs, including the Oregon Health Plan, the state Medicaid program.
A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds. Study results, to be presented Tuesday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla., found that some of these negative effects happened because of an increase in the actions of glucocorticoids, or stress hormones, in the skeleton.
Navy Commander (Dr.) Jonathan A. Forsberg, professor and director of the DOD Osseointegration Program and Musculoskeletal Oncology in the Uniformed Services University of the Health Sciences-Walter Reed National Military Medical Center (USU-WRNMMC) Department of Surgery, has been selected to receive the 2017 Ellis Island Medal of Honor.
When the pros take the field today for Opening Day, many of the sport’s Little League and high school athlete counterparts also will be back in action. With that, however, comes a hazard that doesn’t discriminate by a player’s age or skill level: musculoskeletal problems tied to excessive pitching.
A new study suggests that middle-age and elderly men are less likely to develop worsening frailty if they have high levels of certain anabolic hormones, which are muscle- and bone-building hormones. The study results will be presented Sunday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.
Lindsey Konkel, a New Jersey-based freelance reporter, received the Endocrine Society’s annual Award for Excellence in Science and Medical Journalism, the Society announced today.
Insufficient sleep, a common problem that has been linked to chronic disease risk, might also be an unrecognized risk factor for bone loss. Results of a new study will be presented Saturday at the Endocrine Society’s 99th annual meeting in Orlando, Fla.
The Endocrine Society and Medscape announced today a new partnership that brings together the Society’s expertise and Medscape’s innovative, peer-to-peer digital platforms and award-winning content to provide clinicians with the latest guidance and most relevant insights on diagnosing and treating diabetes, obesity, osteoporosis, infertility, and other endocrine disorders.
The human brain's cerebellum controls the body's ability to tightly and accurately coordinate and time movements as fine as picking up a pin and as muscular as running a foot race. Now, Johns Hopkins researchers have added to evidence that this structure also helps transfer so-called motor learning from one part of the body to another.
The Endocrine Society is proudly partnering with the March for Science, which will bring together more than 100 scientific organizations on Saturday, April 22 to celebrate science and rally public support for publicly funded research.
New treatments for osteoporosis are desperately needed. Two University of Delaware scientists report estimates of potentially the most effective dosage of a particular peptide, with results that could raise density levels in badly degraded bones back to healthy levels.
Researchers from the Mechanobiology Institute, Singapore at the National University of Singapore have described, for the first time, the ordered arrangement of myosin-II filaments in actin cables of non-muscle cells.
Knee replacement surgery for patients with osteoarthritis, as currently used, provides minimal improvements in quality of life and is economically unattractive, according to a study led by Mount Sinai researchers and published today in the BMJ. However, if the procedure was only offered to patients with more severe symptoms, its effectiveness would rise, and its use would become economically more attractive as well, the researchers said.
Music therapy has been found to decrease pain in patients recovering from spine surgery, compared to a control group of patients who received standard postoperative care alone.
Typically, orthopaedic surgeons can get athletes back to their sport with ACL reconstruction surgery. But what happens when the reconstruction surgery isn’t successful?
The American Chiropractic Association (ACA), during its annual House of Delegates meeting March 17, approved a resolution to adopt clinical practice guidelines for the treatment of low back pain from the American College of Physicians (ACP) and the Council on Chiropractic Guidelines and Practice Parameters (CCGPP). The association seeks to direct its members, payers and policy makers toward shared interpretations of current evidence-based best practices.
Osteoporosis affects more than 200 million people worldwide and is a serious public health concern, according to the National Osteoporosis Foundation. Now, Pamela Hinton, associate professor in the Department of Nutrition and Exercise Physiology, has published the first study in men to show that long-term, weight-bearing exercises decrease sclerostin, a protein made in the bone, and increase IGF-1, a hormone associated with bone growth. These changes promote bone formation, increasing bone density.
UCLA researchers have discovered the molecular basis of an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD. Using both fruit flies and human cells the researchers discovered how IBMPFD mutations cause cellular damage, and identified two compounds that are able to reverse the mutations effects. The findings suggest potential strategies to combat IBMPFD and other diseases, including ALS.
An international research team led by the University of Michigan Life Sciences Institute is changing the understanding of the key cellular and molecular events that trigger graft-versus-host disease, an often fatal complication of bone marrow transplants.
Age, gender and frequency of physical therapy utilization after an Anterior Cruciate Ligament (ACL) surgery may be correlated with second ACL reconstruction rates, according to researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s Specialty Day today.
Professional baseball players struggle to return to a high level of play after biceps tenodesis (BP) surgery, according to research presented today at the American Orthopaedic Society for Sports Medicine’s (AOSSM) Specialty Day in San Diego. The study examined how players with SLAP tears responded to biceps tenodesis.
A majority of Anterior Cruciate Ligament (ACL) reconstruction patients develop a condition known as posttraumatic osteoarthritis (PTOA) within 15 years of surgery, which can be debilitating and limit activity. Researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s (AOSSM) Specialty Day in San Diego are highlighting how a set of biomarkers on the day of surgery may explain why some individuals have worse PTOA than others after two years.
Kristy Weber, MD, chief of Orthopaedic Oncology for the University of Pennsylvania Health System and director of the Sarcoma Program in the Abramson Cancer Center, is poised to become the first woman to lead the American Academy of Orthopaedic Surgeons (AAOS). Weber will serve as second vice president from 2017 to 2018, as first vice president from 2018 to 2019, and she will become the Academy’s president in 2019.
A study at Hospital for Special Surgery finds ligament reconstruction is an effective treatment for kneecap instability in patients with trochlear dysplasia.
Patients undergoing total hip replacement experience meaningful and lasting improvements in quality of life (QOL) through at least five years after the procedure, reports a study in the March 15 issue of The Journal of Bone & Joint Surgery. The journal is published by Wolters Kluwer.
Whether you’re younger than 65 or older than 75, age may not be a discernible factor in the success of shoulder replacement surgery, according to a Henry Ford Hospital study.
A less strenuous form of exercise known as whole-body vibration (WBV) can mimic the muscle and bone health benefits of regular exercise in mice, according to a new study published in the Endocrine Society’s journal Endocrinology.
A new study reports that PJK risk following lumbar spinal fusion depends on the level of the spine fused. Specifically, the authors – who include members of the International Spine Study Group (ISSG) from multiple academic centers – found that fusing the lower portion of lumbar spine results in a decreased risk of PJK.
Bone morphogenetic proteins, commonly used off-label to enhance pediatric spinal fusion, did not improve revision rates for pediatric spinal fusion, according to a study by researchers at Hospital for Special Surgery.
A Hospital for Special Surgery study finds that in morbidly obese patients, bariatric surgery performed prior to a total hip or knee replacement can reduce in-hospital and 90-day postoperative complications and improve patient health.