Feature Channels: Diabetes

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BOSTON – (March 25, 2021) – A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring. According to researchers, the key lies with a protein called SOD3, vitamin D and adequate exercise, with the outcomes possibly forming the first steps to designing rational diet and exercise programs to use during pregnancy and particularly when mothers may also be overweight or obese.

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UNC School of Medicine scientists found that HIV boosts a key process in human cells to fuel its replication. They also found that the diabetes drug metformin inhibits that process and thereby suppresses HIV replication in these cells in cell lines and animal models.

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Examining data at a city level can inform more targeted local policy interventions and programming to promote health equity, find researchers.

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Incorporating sweet potato puree into bread not only adds vitamin A, but also changes the starch composition by increasing the fiber content. That can be beneficial for diabetics.

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Endocrine Society selected Hydelene Dominguez, M.D., as the first winner of the C. Wayne Bardin International Travel Award. The award was established to pay tribute to Bardin, who passed away in 2019 and made remarkable research contributions to both reproductive physiology and contraception throughout his long career.

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A new once-weekly basal insulin injection demonstrated similar efficacy and safety and a lower rate of low blood sugar episodes compared with a daily basal insulin, according to a phase 2 clinical trial. The study results, which will be presented at ENDO 2021, the Endocrine Society’s annual meeting, compared an investigational drug called basal insulin Fc (BIF) with insulin degludec, a commercially available long-lasting daily insulin, in patients with type 2 diabetes.

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One in five adults with type 1 diabetes who require in-hospital treatment of the life-threatening condition diabetic ketoacidosis has an unplanned repeat hospital visit within a month and is twice as likely to die during the second hospitalization, a new study finds. The results, which will be presented at ENDO 2021, the Endocrine Society’s annual meeting, also identified several factors that increased the readmission risk for these patients.

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Some patients with moderate to severe COVID-19 disease seem to experience inflammation of the thyroid gland that is different from thyroid inflammation caused by other viruses, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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Children with poorly controlled type 1 diabetes have a 10 times higher risk of COVID-19-related complications and death compared to those with well-controlled diabetes, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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Commonly used medications for type 2 diabetes and obesity called glucagon like peptide-1 receptor agonists (GLP-1 RAs), are not associated with an increased risk of breast cancer, despite previous studies that suggested a possible link, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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New genetic research suggests men can develop characteristics of polycystic ovary syndrome (PCOS)—a common metabolic and reproductive disorder that affects women. The study was presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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People with type 1 diabetes can improve their blood sugar control while reducing time with low blood sugar, or hypoglycemia, using Insulet Corporation’s Omnipod 5 Automated Insulin Delivery System compared to their standard insulin therapy. Results from an industry-sponsored study of the latest Omnipod, the first tubeless, wearable insulin pump, will be presented at ENDO 2021, the Endocrine Society’s annual meeting.

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Patients hospitalized with COVID-19 have worse outcomes if they have high blood sugar, or hyperglycemia, regardless of whether they have diabetes, a new study finds. The researchers will present their results, of the first known study of the impact of hyperglycemia on a largely Black patient population with the novel coronavirus, at ENDO 2021, the Endocrine Society’s annual meeting.

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Black women with polycystic ovary syndrome (PCOS) have higher risk factors for heart disease, diabetes and stroke compared with white women, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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Women with obesity and polycystic ovarian syndrome (PCOS) are at increased risk of developing type 2 diabetes, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting. Normal-weight women with PCOS are not at increased risk, the researchers found.

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Blood glucose levels improved among children and teens with type 1 diabetes during the first 12 weeks of COVID-19 lockdown in the United Kingdom, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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Among women who develop diabetes during pregnancy, night owls have a higher risk of complications for mother and baby than early birds do, according to a study whose results will be presented at ENDO 2021, the Endocrine Society’s annual meeting.

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Two-thirds of patients with chronic endocrine health problems who need close monitoring say they would like to continue with telemedicine follow-up visits after the COVID-19 pandemic ends, according to a survey that will be presented virtually at ENDO 2021, the Endocrine Society’s annual meeting. Three-quarters of providers also said they want to continue with telehealth after the pandemic.

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Treatment of hypothyroidism, which results from an underactive thyroid gland, should be individualized and consideration should be given to alternatives to the first-line therapy, including desiccated thyroid extract and combination therapy to replace the body’s two main thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Results of their new randomized clinical study are being presented at ENDO 2021, the Endocrine Society’s annual meeting.

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People who start eating before 8:30 a.m. had lower blood sugar levels and less insulin resistance, which could reduce the risk of developing type 2 diabetes, according to a study presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.

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Researcher at Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School has received $400,000 in awards to help identify and overcome multi-level factors such as patient, health professionals and clinic systems affecting optimal use of colorectal cancer preventative screening options for patients with elevated medical and social risks throughout the United States.

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The Endocrine Society has selected five recipients for its Early Investigators Awards.

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Sugar is added to many common foodstuffs, and people in Switzerland consume more than 100 grams of it every day.

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Researchers from Rutgers Cancer Institute of New Jersey previously identified a small protein called Rab1A that regulates amino acid signaling. In a recent study, researchers explored the physiological role of Rab1A in mammals using mice though a technique in which one of an organism's genes is made inoperative, known as genetic knockout.

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A disruption to organ rhythms caused by shift work is a key factor in injury-induced disease development, according to a new research article published in the America Journal of Physiology-Renal Physiology.

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For people who are overweight or obese and have type 2 diabetes, the first line of treatment is usually lifestyle intervention, including weight loss and increased physical activity. While this approach has cardiovascular benefit for many, it can be detrimental for people who have poor blood sugar control, according to a study conducted by researchers at Wake Forest School of Medicine.

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Estima-se que uma a cada dez pessoas ao redor do mundo tem doença renal crônica, mas a maioria delas não sabe disso. A falta de conhecimento é particularmente preocupante porque as pessoas com doença renal crônica que se infectarem com COVID-19 têm maior risco de apresentar a forma grave da doença.

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Se calcula que 1 de cada 10 personas en el mundo sufre de insuficiencia renal crónica, pero la mayoría de ellas no lo saben. Ese desconocimiento es particularmente preocupante porque cuando alguien con insuficiencia renal crónica se infecta con la COVID-19, tiene mucho más riesgo de enfermar gravemente.

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Researchers will explore how diabetes, obesity and other endocrine conditions impact the course of the COVID-19 pandemic during the Endocrine Society’s ENDO 2021 virtual news conferences March 22-23.

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Translational research led by scientists at La Jolla Institute for Immunology (LJI) has resulted in a promising combination therapeutic candidate for adults with recent-onset type 1 diabetes.

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While it’s an unfair reality that women who develop gestational diabetes are ten times more likely to develop type 2 diabetes later in life, only a third of these women realise that they’re at high risk, according to new research by the University of South Australia.

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An estimated 1 in 10 people worldwide have chronic kidney disease, but most of them don't know it. That lack of awareness is especially concerning because people with Chronic kidney disease who are infected with COVID-19 are at higher risk for serious illness.

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The Endocrine Society is excited to announce the selection of Kate Fryer as the organization’s next chief executive officer. Fryer has served in numerous scientific association leadership positions with deep experience in strategic planning, membership, scientific publishing, communications, society operations, as well as meetings and conferences.

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The length of the female reproductive period (the time from the onset of menses to the final menstrual period) has important health implications.

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A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study.

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Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study. The findings, published online in PNAS, could offer a new way to treat both Type 1 and Type 2 diabetes in people.

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The Association of Diabetes Care & Education Specialists Foundation and the Certification Board for Diabetes Care and Education are accepting applications for a one-year mentored postdoctoral fellowship in integrated diabetes management.

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Long thought a vestigial part of human cells, new genetic analysis of the primary cilium shows that it may be tied to common conditions like diabetes and kidney failure

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An experimental treatment can essentially reverse type 1 diabetes in certain types of laboratory mice, according to a series of studies led by University of Utah Health scientists. An injection of the therapeutic agent converts cells that normally control glucose production into ones that generate insulin.

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Basic biology finding on thyroid hormone function could lead to new treatments for obesity, diabetes and related disorders

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A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

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Antipsychotic drugs not only block dopamine signaling in the brain but also in the pancreas, leading to uncontrolled production of blood glucose-regulating hormones and, eventually, obesity and diabetes.

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In a recent study, published in The Journal of Clinical Investigation, University Hospitals (UH) Cleveland Medical Center and Case Western Reserve University School of Medicine researchers have found that skeletal muscle significantly affects how the body stores and metabolizes fat.

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The 10-member team made discoveries about a specific area of the brain tied to recollection and the desire to seek and consume food. It could lead to a way to inhibit the desire to overeat.

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New research in mice suggests that exercising during pregnancy may help prevent children—especially boys—from developing health problems related to their parents’ obesity. The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for February.

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Older adults who are classified as having “prediabetes” due to moderately elevated measures of blood sugar usually don’t go on to develop full-blown diabetes.

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Cardiac patients who also have diabetes will be able to do their rehabilitation exercises more safely, thanks to the world's first guidance on the subject, which has been published by international experts including a Swansea University academic.

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DALLAS – Feb. 3, 2021 – Gaining more fat cells is probably not what most people want, although that might be exactly what they need to fight off diabetes and other diseases. How and where the body can add fat cells has remained a mystery – but two new studies from UT Southwestern provide answers on the way this process works.

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During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.