Feature Channels: Diabetes

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Six key domains outline specific sets of knowledge, skills and abilities critical to the role

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The Endocrine Society today announced it has chosen 15 leading endocrinologists as winners of its prestigious 2021 Laureate Awards, the top honors in the field.

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DALLAS – Aug. 25, 2020 – Breastfeeding secures delivery of sugar and fat for milk production by changing the insulin sensitivity of organs that supply or demand these nutrients, a new study led by UT Southwestern scientists suggests. The findings, published in this month’s print issue of Diabetes, could explain how different tissues cooperate to start and maintain lactation and offer strategies to help improve breastfeeding success for mothers who have insufficient milk production.

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A new study finds women with diabetes and significant levels of calcium in their coronary arteries have higher rates of death from cardiovascular disease and all causes than their male counterparts.

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Air pollution is the world’s leading environmental risk factor, and causes more than nine million deaths per year. New research published in the Journal of Clinical Investigation shows air pollution may play a role in the development of cardiometabolic diseases, such as diabetes. Importantly, the effects were reversible with cessation of exposure.

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A longstanding theory has suggested that gastric bypass surgery may have unique, weight loss-independent effects in treating type 2 diabetes. But new research from Washington University School of Medicine in St. Louis indicates that weight loss after surgery, rather than the surgery itself, drives metabolic improvements, such as the remission of diabetes.

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When it comes to improving care, patients really thrive with a little TLC. Researchers from Emory University, University of Washington School of Medicine, and their colleagues in India compared a collaborative care model with usual care in 404 patients with diabetes and moderate-to-severe depressive symptoms. More than 70 percent in the group receiving the integrated approach had improvements in diabetes and depression. The key to the model is creating patient-care managers who coordinate care with doctors, nurses and family members. The patients thrive with this kind of attention.

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These days it’s hard not to worry about whether a quick outing to the grocery store will result in catching COVID-19. But for parents with children who have preexisting health conditions such as diabetes, it can be especially hard not to worry about whether their child is at a higher risk of becoming severely ill from the virus.

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ADCES is an interdisciplinary professional membership organization dedicated to improving prediabetes, diabetes and cardiometabolic care through innovative education, management and support. With more than 12,000 professional members including nurses, dietitians, pharmacists and others, ADCES has a vast network of practitioners working to optimize care and reduce complications. ADCES offers an integrated care model that lowers the cost of care, improves experiences and helps its members lead so better outcomes follow. Learn more at DiabetesEducator.org, or visit us on Facebook or LinkedIn (Association of Diabetes Care & Education Specialists), Twitter (@ADCESdiabetes) and Instagram (@ADCESdiabetes).

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Pharmacist Candis Morello, PharmD, of Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego, discusses her Diabetes Intensive Medical Management (DIMM) “tune up” clinic for complex type 2 diabetes patients – and why this team-based approach is better for patients and more cost effective for health systems and payers.

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Preliminary observations of COVID-19 patients with diabetes inspired an algorithm for glucose monitoring that’s suspected to help combat the virus’ serious complications.

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A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life.

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Value in Health, the official journal of ISPOR, announced today the publication of a series of articles focused on recent developments in the field of health preference research.

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Researchers from Tufts have discovered neural mechanisms in mice specific to females that switch estrogen from playing a protective role in glucose metabolism to a disruptive role. The discovery could provide clues to the increased risk of insulin resistance and diabetes among post-menopausal women.

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New research shows significantly more people with diabetes got their critical annual dilated eye exam during the first two years following Medicaid expansion under the under the Affordable Care Act (ACA). However, this encouraging increase in the exam rate did not persist beyond two years.

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In a new study published in Diabetes Care, researchers at Children’s Hospital of Philadelphia (CHOP) have found that youth who are involved with the decision to start CGM are more likely to continue using the monitoring technology more than two months after starting. The findings suggest that children and adolescents who do not have a role in the decision are less likely to be satisfied with the device and use the device consistently.

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Faculty from Wayne State University’s Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment.

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Researchers have discovered a new drug candidate that offers a major advance to treat diabetes. Tested on human and mouse pancreatic islets, mouse and rat cell cultures and animal models of Type 1 and Type 2 diabetes, the drug significantly improved four detrimental characteristics of diabetes.

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Albert Einstein College of Medicine has received a $9.5 million, five-year grant from the National Institutes of Health (NIH) to support the Einstein-Mount Sinai Diabetes Research Center (ES-DRC). The multi-institutional center is a leader in basic, translational, clinical, and community-based research and training in type 1 and type 2 diabetes, obesity, and other metabolic disorders.

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Although additional policies are needed to relieve insulin’s financial burden, researchers find a national cost-sharing cap helps privately insured children and young adults with type 1 diabetes pay less out-of-pocket.

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DALLAS – July 23, 2020 – Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows. The findings, reported in a recent issue of PNAS, could shed light on Type 2 diabetes and other insulin resistance disorders, which remain poorly understood despite decades of study.

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Early menstruation increases the likelihood of hot flushes and nights sweats decades later at menopause, according to a University of Queensland study.

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Experiences of racism are associated with lower subjective cognitive function (SCF) among African-American women.

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A growing number of chemicals in pesticides, flame retardants, and certain plastics have been linked to widespread health problems including infertility, diabetes, and impaired brain development, a set of reviews of hundreds of studies concludes.

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Children with type 1 diabetes have a less desirable gut microbiome composition which may play a role in the development of the disease, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Cinnamon improves blood sugar control in people with prediabetes and could slow the progression to type 2 diabetes, according to a new study published in the Journal of the Endocrine Society.

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Researchers at Joslin Diabetes Center have discovered that some benefits of aerobic exercise may be dampened by higher-than-normal blood sugar levels, and that this is independent of obesity and insulin levels in the blood.

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The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated.

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A study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine finds a link between the stress hormone cortisol and higher blood sugar levels in people with type 2 diabetes.

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World-first plasma-coated bandages with the power to attack infection and inflammation could revolutionise the treatment of chronic wounds such as pressure, diabetic or vascular ulcers that won't heal on their own. Developed by the University of South Australia, the novel coating comprises a special antioxidant which can be applied to any wound dressing to simultaneously reduce wound inflammation a¬¬nd break up infection to aid in wound repair.

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New research published in Nature Communications uses a technology first developed at the University of Miami Miller School of Medicine to enhance the oxygenation of cultured tissues that will likely be able to conduct real-time regeneration and development studies in the human pancreas.

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Philadelphia’s tax on sweetened beverages led to a 38.9 percent drop in the volume of taxed beverages sold at small, independent retailers and a significant increase in the price of taxed beverages, according to new research from the Perelman School of Medicine at the University of Pennsylvania. This study builds on previous research that suggests beverage taxes can help reduce purchases of sugary drinks, led by Christina Roberto, PhD, an associate professor of Medical Ethics and Health Policy at Penn, and senior author on this latest paper published in Health Affairs.

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The age of insulin parcels may matter, researchers say, when it comes to diagnosing and treating diabetes.

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A team of paediatric specialists, including an expert from the University of Adelaide, has produced new guidelines regarding assessment and management of type 2 diabetes (T2D) in Australian and New Zealand children and adolescents.

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In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

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People with endocrine disorders may see their condition worsen as a result of COVID-19, according to a new review published in the Journal of the Endocrine Society.

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Largest US database of pregnant women with type 1 diabetes provides a first-time, big picture view of mother’s health, and neonatal and delivery outcomes. The analysis found a threefold increase in insulin pump use at the end of the study period, compared to the start of the study, but A1c levels remained steady across the 13-year period. Over time the study showed a trend toward pre-pregnancy obesity and unhealthy maternal weight gain.

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In addition to its predictive value, the discovery could lead to new treatments to prevent deadly cytokine storms. It also may help explain why diabetes contributes to worse outcomes in patients with COVID-19.

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Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival. Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. A multi-institution randomized clinical trial of a drug used to control uric acid did not show the desired clinical benefits, but did give a very clear answer to an important scientific question.

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Diabetes organizations collaborate to offer mentored fellowship in integrated diabetes management. Applications must be submitted by July 31, 2020.

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Heart failure posed the greatest 5-year risk of death for people newly diagnosed with Type 2 diabetes than any other heart or kidney diseases, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

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UCLA scientists have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples. By speeding up research, investigators hope to accelerate the diagnosis of people living with mitochondrial diseases and secondary disorders in which mitochondria play a key role, including diseases related to aging, metabolism and the heart.

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The 2020 Warren Alpert Foundation Prize has been awarded to a trio of researchers for seminal discoveries about the function of key intestinal hormones, their effects on metabolism and the subsequent design of treatments for type 2 diabetes, obesity and short bowel syndrome.

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Diabetic ketoacidosis is a common and potentially fatal complication in hospitalized patients with COVID-19, according to a new clinical perspective published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Fewer than one in five adolescents and young adults with type 1 diabetes are successful in achieving the recommended 2019 A1C goal of below 7.5%, and the overwhelming majority fail to achieve the 2020 target of less than 7%. But young people who use continuous glucose monitoring (CGM) devices can significantly improve their overall blood glucose control, without increasing severe low or high glucose levels, according to findings from a 6-month, multi-center clinical trial. And both severe hypoglycemia (low glucose) and hyperglycemia (high glucose) can lead to emergency care and hospitalization.

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Cholesterol levels are declining sharply in western nations, but rising in low- and middle-income nations - particularly in Asia, according to a study of global cholesterol levels, which involve researchers at the University of Gothenburg.

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Access the latest in diabetes, prediabetes and cardiometabolic care at the Virtual ADCES 2020 Annual Conference from Thursday, Aug. 13 to Sunday, Aug. 16.