Men with newly diagnosed metastatic, hormone-sensitive prostate cancer lived more than a year longer when they received a chemotherapy drug as initial treatment instead of waiting to for the disease to become resistant to hormone-blockers, report scientists from Dana-Farber Cancer Institute and the Eastern Co-operative Oncology Group.
Significant improvement with the use of a combination drug therapy for recurrent ovarian cancer was reported at the annual meeting of the American Society of Clinical Oncology (ASCO) meeting in Chicago.
At the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO), University of Colorado Cancer Center researchers reported results of a Phase I trial of OMP-54F28 (FZD8-Fc), an investigational drug candidate discovered by OncoMed Pharmaceuticals targeting cancer stem cells (CSCs).
Key studies released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) identify new strategies for easing the short- and long-term effects of cancer therapy and improving the quality of life of patients with cancer, as well as their caregivers.
A University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) draws a line from mutation of the gene NTRK1, to its role as an oncogene in non-small cell lung cancer, to treatment that targets this mutation.
A study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) describes the results of a phase I clinical trial of the investigational agent DMOT4039A against pancreatic and ovarian cancers. In this early clinical trial with the goal of identifying possible risks and defining likely dosages, the drug was well tolerated and in some patients showed initial evidence of anti-cancer activity.
Cancer panel reveals new insights in HPV cancers.
Among young breast cancer patients, one of the most distressing side effects of chemotherapy is early menopause. But a major study finds the risk of early menopause can be significantly reduced by adding the drug goserelin to the chemotherapy regimen.
Women with metastatic breast cancer to the bone may be able to receive bisphosphonates, the bone-targeting class of drugs like zoledronic acid, less often after the first year of monthly administration. With that practice change, women may also reduce their risk of serious side effects, according to a study led by researchers at The University of Texas MD Anderson Cancer Center.
People in the late stages of cancer and other terminal illnesses are not only unharmed by discontinuing statins for cholesterol management, they may benefit, according to a study presented Friday by researchers at Duke Medicine representing a national research network.
The majority of women with cancer causing BRCA1 and BRCA2 mutations experience sexual dysfunction, menopausal symptoms, cognitive and stress issues, and poor sleep following prophylactic removal of their Fallopian tubes and ovaries - a procedure known as risk-reducing salpingo-oophorectomy (RRSO) - according to results of a new study from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania.
Among men treated for prostate cancer, those who received radiation therapy were more likely to develop bladder or rectal cancer, according to a new study from the University of Michigan Comprehensive Cancer Center.
A pilot study by Indiana University researchers found that whole-body vibration exercise may reduce pain symptoms and improve aspects of quality of life in individuals diagnosed with fibromyalgia.
Indiana University researchers say a little deception caused cyclists in their 4K time trial to up their performance even after they realized they had been tricked.
A rare type of melanoma that disproportionately attacks the palms and soles and under the nails of Asians, African-Americans, and Hispanics, who all generally have darker skins, and is not caused by sun exposure, is almost twice as likely to recur than other similar types of skin cancer, according to results of a study in 244 patients.
Amphetamines can delay exhaustion during exercise in the heat by increasing the temperature at which it occurs. The potential cost? The risk of suffering from exertional heat stroke.
It’s something we’ve all heard for years: Exercise can help keep older adults healthy. But now a study, the first of its kind, proves that physical activity can help older adults maintain their mobility and dodge physical disability.
In March of this year, a team of Georgetown University scientists published research showing that, for the first time ever, a blood test has the potential to predict Alzheimer’s disease before patients start showing symptoms. AACC is pleased to announce that a late-breaking session at the 2014 AACC Annual Meeting & Clinical Lab Expo in Chicago will expand upon this groundbreaking research and discuss why it could be the key to curing this devastating illness.
Researchers following almost 450 children enrolled in the Pediatric HIV/AIDS Cohort Study, one of the largest studies of HIV-positive children in the United States, found that 74 percent had developed resistance to at least one form of drug treatment.
Late Pulmonary Function Abnormalities are Common Among Iraq/Afghanistan Veterans
ATS 2014, SAN DIEGO – Sure, everyone knows a healthy diet provides lots of health benefits for patients with respiratory diseases, but now a new study has shown a direct link between eating fish, fruit and dairy products and improved lung function among patients with chronic obstructive pulmonary disease (COPD).
Reminders prompting asthma patients to take their control inhalers if they miss a dose significantly improve medication adherence, according to a primary-care based study conducted by a research team in Australia. In this six-month investigation, patients receiving reminders took on average 73% of their prescribed doses compared to only 46% in patients who did not have reminders.
Mayo Clinic urologists will present studies on a new non-mesh outpatient procedure for treating female stress incontinence stress incontinence, lymph node surgery guided by 11c-Choline imaging for patients with nodal recurrent prostate cancer, a Prostate Specific Antigen (PSA) cut point correlated with systemic progression of prostate cancer, an increased mortality risk for diabetes patients undergoing surgery for kidney cancer and other research at the 2014 Annual meeting of the American Urological Association, May 16–21, in Orlando, Fla. Mayo Clinic experts will also be available to provide comment for reporters covering the conference. Studies to be presented at the meeting and their embargo dates include:
Bacteria found in the nose may be a key indicator for future development of skin and soft-tissue infections in remote areas of the body.
Maternal intake of dietary methyl donors during the first trimester of pregnancy modulates the risk of developing childhood asthma at age 7, according to a new study presented at the 2014 American Thoracic Society International Conference.
Both high and low frequency hearing impairment have been linked with sleep apnea in a new study of nearly 14,000 individuals.
ATS 2014, SAN DIEGO ─ The link between stroke and obstructive sleep apnea (OSA) has been established by several clinical studies in recent years, with the most significant risks attributed to male patients. Now, a new study by researchers from Boston says the link between OSA and stroke may be just as strong among women.
Research from Rutgers Cancer Institute of New Jersey shows that the ‘first in man’ series of vaccine injections given directly into a pancreatic cancer tumor is not only well tolerated, but also suggests an “encouraging” period of stable disease. Results from a Phase I clinical trial conducted at the Cancer Institute of New Jersey are being presented at the American Association for Cancer Research (AACR) Pancreatic Cancer conference in New Orleans this week.
Researchers at UNC Health Care have found that using a new method for identifying bacteria and fungi in patient specimens led to a 92 percent cost reduction in the reagents needed to run clinical microbiology tests.
In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference.
Cigarette smoking and male sex are significant risk factors for developing ocular sarcoidosis, according to a new study presented at the 2014 American Thoracic Society International Conference.
In what is believed to be the largest and most detailed genetic analysis of its kind, researchers at NYU Langone Medical Center and elsewhere have concluded that 69 percent of healthy American adults are infected with one or more of 109 strains of human papillomavirus (HPV).
ATS 2014, SAN DIEGO ─ Pulmonary hypertension patients from lower socioeconomic groups present for initial evaluation at a more advanced disease state than those from higher income groups, according to a new study presented at the 2014 American Thoracic Society International Conference.
In patients with congestive heart failure, obesity and a larger waist size have paradoxically been associated with a better prognosis in the prior investigations. This effect, known as the obesity paradox phenomenon, is now being demonstrated in patients with severe pulmonary hypertension.
Home testing of obstructive sleep apnea (OSA) followed by initiation of home treatment with an auto-titrating continuous positive airway pressure (CPAP) device reduced costs compared with in-laboratory testing and titration without negatively impacting clinical outcomes, researchers have shown in a new study presented at the American Thoracic Society International Conference.
A pedometer-based walking program supported by Internet-based instruction and support can improve health-related quality of life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD), according to a new study presented at the 2014 American Thoracic Society International Conference.
A large study of intensive care patients in California found that public reporting of patient outcomes did not reduce mortality, but did result in reduced admission of the sickest patients to the ICU and increased transfer of critically ill patients to other hospitals.
Taking olive oil supplements may counteract some of the adverse cardiovascular effects of exposure to air pollution, according to a new study presented at the 2014 American Thoracic Society International Conference.
Patients who have survived a stay in the intensive care unit (ICU) have a greatly increased risk of developing symptoms of post-traumatic stress disorder (PTSD), according to a new study presented at the 2014 American Thoracic Society International Conference.
Individuals with dyspnea, or shortness of breath, have an increased long-term mortality risk compared with individuals without dyspnea, according to a new study presented at the 2014 American Thoracic Society International Conference.
After a year of being treated with a novel drug, patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and those with persistent or recurrent pulmonary hypertension after an operation for the disease showed sustained improvement in a multicenter, international trial presented at the 2014 American Thoracic Society International Conference.
Children who are exposed in utero to high levels of particulate air pollution during the second trimester of pregnancy may be at greater risk of developing asthma in early childhood, according to a new study presented at the 2014 American Thoracic Society International Conference.
Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria
Although it’s present in only a tenth of all patients who are admitted to the hospital, sepsis contributes to up to half of all hospital deaths in the U.S., according to a study presented at the American Thoracic Society’s annual conference here.
If you suffer from COPD, staying cool this summer may provide much more significant benefits than simply feeling more comfortable. A study from researchers at Johns Hopkins University says it may also keep you healthier. The study found COPD patients who were exposed to warm indoor temperatures had greater disease-related morbidity, including an increase in symptoms, a rise in the use of rescue medications and a decline in lung function. Higher outdoor temperatures were also associated with increased COPD symptoms.
ATS 2014, SAN DIEGO ─ Clinically important sleep apnea is common among survivors of acute respiratory failure, according to a new study presented at the 2014 American Thoracic Society International Conference.
ATS 2014, SAN DIEGO ─ A new study by researchers from California and Canada indicates a simple urine test can indicate the presence of venous thromboembolism, a blood clot that has broken free from its point of origin and which travels through the bloodstream, eventually lodging in a vein. The test evaluates the levels of fibrinopeptide B (FPB), a small peptide that’s released when a thrombosis forms and which is removed from the body through urine.
Patients with chronic pulmonary thromboembolic disease may benefit from pulmonary thromboendarterectomy (PTE), even if the patients don’t have severe pulmonary hypertension, according to University of California, San Diego, researchers.
ATS 2014, SAN DIEGO ─ As if increased risks of high blood pressure, respiratory infections, lung cancer and even depression weren’t enough, researchers say patients with chronic obstructive pulmonary disease (COPD) have another complication to worry about: heart failure.
Women plagued by repeated urinary tract infections may be able to prevent the infections with help from over-the-counter painkillers, new research in mice shows. Scientists at Washington University School of Medicine in St. Louis found that inhibiting COX-2, an immune protein that causes inflammation, eliminated recurrent urinary tract infections in the mice.
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