Women plagued by repeated urinary tract infections may be able to prevent the infections with help from over-the-counter painkillers, new research in mice shows. Scientists at Washington University School of Medicine in St. Louis found that inhibiting COX-2, an immune protein that causes inflammation, eliminated recurrent urinary tract infections in the mice.
Bacteria live in the bladders of healthy women, discrediting the common belief that normal urine is sterile. This finding was presented today by researchers from Loyola University Chicago at the 114th General Meeting of the American Society for Microbiology in Boston.
A vast majority of so-called “super-frequent user” patients who seek care in the Emergency Department (ED) have a substance abuse addiction, according to a Henry Ford Hospital study. A patient is considered a super-frequent user who visits the ED at least 10 times a year.
Beverly J. Lange, M.D., an exemplary physician and researcher at The Children’s Hospital of Philadelphia (CHOP) for over 40 years, will receive the 2014 Distinguished Career Award from the American Society of Pediatric Hematology/Oncology (ASPHO).
The Advances in Neuroblastoma Research Association (ANRA) is conferring its highest honor, the ANRA Lifetime Achievement Award, on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children’s Hospital of Philadelphia (CHOP).
Tinnitus affects roughly 50 million people and is now the No. 1 disability among our men and women in uniform, costing the U.S. about $1.7 billion a year to treat. But even with these staggering numbers, there's still no know cure for tinnitus. Today, Dr. Michael Seidman, a national leader in the treatment and study of tinnitus, will present a culmination of years of research at the Combined OTO Spring Meetings in Las Vegas.
Despite claims suggesting otherwise, inappropriate cancer patient demands are few and very rarely lead to unnecessary tests and treatments from their health care providers, according to new results from a study that will be presented by researchers in the Abramson Cancer Center (ACC) and the Perelman School of Medicine at the University of Pennsylvania during the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago in early June (Abstract #6530).
While large genetic testing panels promise to uncover clues about patients’ DNA, a team of researchers from Penn Medicine’s Abramson Cancer Center (ACC) has found that those powerful tests tend to produce more questions than they answer.
Researchers from University Hospitals (UH) Case Medical Center’s Seidman Cancer Center will present findings from a study that found the presence of tumor-infiltrating lymphocytes, a type of white blood cell, ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer. The data are being presented at the 50th American Society for Clinical Oncology (ASCO) Annual Meeting in Chicago. “Triple-negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,” says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine. “Our research shows that the presence of lymphocytes before administering chemotherapy could predict a positive response to platinum-based therapy.”
New research from Memorial Sloan Kettering highlighted in advance of the 50th Annual Meeting of the American Society of Clinical Oncology demonstrates the powerful clinical benefit of giving patients a drug that targets the molecular abnormality driving the growth of advanced pigmented villonodular synovitis, a rare and debilitating joint disease.
Vivek Reddy, MD, Director of Arrhythmia Services for The Mount Sinai Hospital, reported his promising12-month follow-up data showing the world’s first leadless pacemaker is demonstrating overall device performance comparable to conventional pacemakers. Dr. Reddy presented the one-year LEADLESS study data findings during his late-breaking clinical trial presentation on May 9 at Heart Rhythm 2014, the Heart Rhythm Society’s 35th Annual Scientific Sessions in San Francisco, CA.
New research from McMaster University suggests that a commonly performed test during certain types of heart surgery is not helpful and possibly harmful.
A smartphone app that monitors subtle qualities of a person’s voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder. While the app still needs much testing before widespread use, early results from a small group of patients show its potential to monitor moods while protecting privacy.
Dr. Matthew Breen's laboratory has developed an extensive cytogenetics “toolbox” designed to provide the necessary means to identify key cytogenetic signatures in numerous canine cancers. His presentations at the 2014 ACVIM Forum will include "Genomics & Genetics in Veterinary Medicine: An Overview” and “Cancer in the Domestic Dog: A Genome With Two Tales."
Researchers have found that patients received similar care for wet age-related macular degeneration (AMD) whether being evaluated by a doctor in-person or remotely. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando, Fla.
In another example of serendipity advancing scientific research, investigators have discovered a new class of drugs to treat an eye condition called nystagmus. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando, Fla.
Scientists have developed a non-invasive technique to determine if individuals carry a gene for an inherited eye disease known as retinitis pigmentosa. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando, Fla.
Scientists have found that pressure from the fluid surrounding the brain plays a role in maintaining proper eye function, opening a new direction for treating glaucoma — the second leading cause of blindness worldwide. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando, Fla.
Experts from the Penn Medicine Cardiovascular Institute and the Cardiac Arrhythmia Program will present new research and participate in expert panel discussions at the 35th Annual Scientific Sessions of the Heart Rhythm Society (HRS) May 7-10, 2014 in San Francisco.
The risk of dying from the most dangerous type of skin cancer is significantly reduced with regular doctor visits, according to a Henry Ford Hospital study. This is believed to be the first study of its kind to link melanoma mortality with routine health care use.
New evidence showing that the MammaPrint® and BluePrint® tests provide insights into how to treat breast cancer was presented at the annual conference of the American Society of Breast Surgeons (ASBrS).
A major new pediatric research study led by a Wayne State University researcher, funded by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) and published this week in the New England Journal of Medicine (NEJM), has “major implications” for the treatment of urinary tract infections (UTIs) in millions of American children.
A new study exposes the risk of nutritional deficiencies in severely obese teens – both those who had weight loss surgery and those who did not.
Approximately three of every four Cincinnati infants heavily breastfeed after the age of six months is not obtaining the level of dietary diversity recommended by the World Health Organization, according to a new Cincinnati Children’s Hospital Medical Center study.
Many cancer patients endure severe pain and, by far, one of the most excruciating pain conditions is caused by oral cancer, for which even the strongest available pain medications are largely ineffective. One of the nation’s leading oral cancer treating clinicians, speaking at the American Pain Society’s annual meeting, said he believes that while prospects for major treatment advances remain bleak, a new cannabinoid-based medication may have some promise for providing meaningful pain relief.
Many Americans have heartburn at least weekly, and could be saving money on medicines to treat it. Survey shows doctors believe generics and name brands work the same for acid reflux and constipation, but they often recommend more expensive brand names.
Teens who drink or use marijuana at school should be screened for exposure to trauma, mental health problems and other serious health risks.
The Medical Alumni Association of the University of Maryland School of Medicine (SOM) along with notable national experts review the cause and end of life issues surrounding the death of one of the most prominent figures of the 20th Century: former First Lady and leading women’s and civil rights advocate Eleanor Roosevelt as part of the 21st Annual Historical Clinicopathological Conference.
Addressing the complexities involved with a pre-surgical treatment regimen for some breast cancer patients, a pair of nurses at Rutgers Cancer Institute of New Jersey explored an educational initiative to better help patients navigate this process. Their research is being presented at the ONS Annual Congress this week.
Mobile medicine is helping chronic pain patients cope with and manage their condition thanks to new smartphone apps, which can track patients from a distance and monitor pain, mood, physical activity, drug side effects, and treatment compliance.
Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer’s disease (AD) that they say is neither well recognized nor treated appropriately.
The American Pain Society today urged private donors to step forward to help fill the pain research grant allocation void caused by federal government cuts by contributing to the new American Pain Society Pain Research Fund, which was announced today at the organization’s annual scientific conference.
A study by UCLA neurologist Rhonda Voskuhl showed that combining estriol, a female hormone, with Copaxone, a current medication for multiple sclerosis, reduced the relapse rate of MS by nearly 50 percent with only one year of treatment.
GAINESVILLE, Fla. --- New University of Florida research suggests that a pitcher’s elbow injury could be linked to movement in the hips.
A new technique that brings CT imaging into the operating room will allow surgeons to precisely demarcate and remove small sub-centimeter lung nodules, leaving as much healthy tissue as possible, according to Raphael Bueno, MD, of Brigham and Women’s Hospital in Boston. His team is presenting the results of this late-breaking research at the 94th AATS Annual Meeting in Toronto, ON, Canada on April 30, 2014.
A new study presenting data from 17 cardiac surgical centers in Virginia, representing 100 surgeons and 99% of cardiac operations performed in the state, demonstrates that, even today, significant variations – among surgeons and hospitals - still exist in the performance of mitral valve repair vs replacement for moderate to severe mitral regurgitation. Significant associations were observed between the propensity for MV repair and both institutional and surgeon annual volume, although increasing surgeon volume appears to be the much stronger predictor.
Researchers at the University of Louisville School of Medicine are using breath analysis to detect the presence of lung cancer. Preliminary data indicate that this promising noninvasive tool offers the sensitivity of PET scanning, and has almost twice the specificity of PET for distinguishing patients with benign lung disease from those with early stage cancer. Michael Bousamra II, MD, Associate Professor, Department of Cardiovascular and Thoracic Surgery, is presenting the results of the study at the AATS 2014 Conference on April 29, 2014.
Children with a heart defect called transposition of great arteries (TGA) are born with the two major blood vessels (aorta and the main lung artery) arising from the wrong sides of the heart. Consequently, blood is pumping inappropriately between the lungs and the rest of the body, a fatal condition unless surgically treated. The surgery of choice, the arterial switch operation (ASO), is usually performed within the first few weeks of life. In a retrospective analysis of 30 years of experience performing ASOs, Hanna A. Jensen, MD, PhD, and the rest of the team led by Victor Tsang, MD, FRCS, from the Great Ormond Street Hospital for Children NHS Foundation Trust in London, suggest that 90-day outcomes may give a more revealing picture than the traditional reliance on 30-day data. She is presenting the results of this research at the 94th AATS Annual Meeting in Toronto.
High-risk operable lung cancer patients have poorer quality of life scores than the normal U.S. population. However surgery can still be undertaken safely: Low global quality of life scores were not associated with lower survival, recurrence-free rate, or for higher risk for adverse events following sublobar resection, a major surgical procedure.
A major new study using data from the National Cancer Data Base details the impact of annual hospital volume on 30- and 90-day mortality rates. Investigators found that major lung surgery has become progressively safer over the last few decades, although higher death rates at low-volume hospitals and an unexpected increase in mortality at 90 days compared to 30 days were observed. The study further suggests that choosing a center that performs major lung surgery regularly can have a strong impact on survival.
A research team at the University of Texas Southwestern Medical Center at Dallas says their new mouse model helps scientists better understand the progression of pancreatic cancer and may provide new avenues for the development of therapies.
The use of transplant organs from animals (xenotransplantation) could help to compensate for the shortage of human organs available for transplant. NIH researchers have demonstrated that by using hearts from genetically engineered pigs in combination with target-specific immunosuppression of recipient baboons, organ survival can be significantly prolonged. This has potential for paving the way for the use of animal organs for transplantation into humans.
Investigators propose that NASA’s “threat and error model” – derived from analyzing >30,000 commercial flights and which explains >90% of crashes – is directly applicable to pediatric cardiac surgery.
A trio of studies from the Perelman School of Medicine at the University of Pennsylvania demonstrate new approaches to understanding, treating and potentially staving off Parkinson's disease (PD). Studies show that factors such as estrogen exposure and statin use have an impact on the onset of Parkinson's disease.
Stroke researchers from the Perelman School of Medicine at the University of Pennsylvania will unveil a map demonstrating geographic hotspots of increased stroke mortality across the United States, among a series of stroke studies being presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
The stress hormone cortisol can negatively affect memory and learning ability in the elderly. Researchers at Loma Linda University found that showing a 20-minute funny video to healthy seniors and seniors with diabetes helped them score better on memory tests and significantly reduced their cortisol levels when compared to non-video watchers.
New research shows that supplementation with zinc might reduce cell stress after the type of blast injury soldiers experience from IEDs.
Presentations at the 2014 Annual Clinical Meeting of the American Congress of Obstetrics and Gynecology (ACOG) being held April 26 – 30 in Chicago.
A quick overview of the 94th AATS Annual Meeting, Toronto, April 26-30, 2014 plus 8 featured presentations.
A new study suggests that targeting B cells, which are a type of white blood cell in the immune system, may be associated with reduced disease activity for people with multiple sclerosis (MS). The study is released today and will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
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